cold Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A group of disorders affecting the bronchi and the lung parenchyma. It is characterized by chronic and irreversible obstruction of the airflow. It includes chronic bronchitis and pulmonary emphysema.|A disease of chronic diffuse irreversible airflow obstruction. Subcategories of COPD include CHRONIC BRONCHITIS and PULMONARY EMPHYSEMA.|A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema. (Experimental Factor Ontology, EFO_0000341)
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Genes

65 genes co-occuring with the biological term cold in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC11 ATP-binding cassette, sub-family C (CFTR/MRP), member 11
ACE2 angiotensin I converting enzyme 2
ADD1 adducin 1 (alpha)
ADRA2C adrenoceptor alpha 2C
ADRB2 adrenoceptor beta 2, surface
AICDA activation-induced cytidine deaminase
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
C19ORF80 chromosome 19 open reading frame 80
C1S complement component 1, s subcomponent
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CHGA chromogranin A
CHRM3 cholinergic receptor, muscarinic 3
CIRBP cold inducible RNA binding protein
CXCR2 chemokine (C-X-C motif) receptor 2
CYB561 cytochrome b561
DDAH2 dimethylarginine dimethylaminohydrolase 2
DHRS4 dehydrogenase/reductase (SDR family) member 4
GHRL ghrelin/obestatin prepropeptide
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
ICAM1 intercellular adhesion molecule 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IL1B interleukin 1, beta
IRF4 interferon regulatory factor 4
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
LEP leptin
LPL lipoprotein lipase
MAOA monoamine oxidase A
MFN2 mitofusin 2
MIR130B microRNA 130b
MIR31 microRNA 31
MMP2 matrix metallopeptidase 2
MSRB3 methionine sulfoxide reductase B3
NLRP12 NLR family, pyrin domain containing 12
NLRP3 NLR family, pyrin domain containing 3
PARP1 poly (ADP-ribose) polymerase 1
PAX5 paired box 5
PF4 platelet factor 4
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
RET ret proto-oncogene
SCGB3A2 secretoglobin, family 3A, member 2
SCN10A sodium channel, voltage gated, type X alpha subunit
SCN4A sodium channel, voltage gated, type IV alpha subunit
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SSTR2 somatostatin receptor 2
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TG thyroglobulin
TLR4 toll-like receptor 4
TP53 tumor protein p53
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPC5 transient receptor potential cation channel, subfamily C, member 5
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV3 transient receptor potential cation channel, subfamily V, member 3
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
WNK1 WNK lysine deficient protein kinase 1
YBX1 Y box binding protein 1
YBX3 Y box binding protein 3