colon polyps Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description abnormal tissue masses that protrude into the lumen of the colon and are tethered to the wall of the colon (Mammalian Phenotype Ontology, MP_0003269)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003269
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Genes

8 gene mutations causing the colon polyps phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
APC adenomatous polyposis coli
CDX2 caudal type homeobox 2
MCM2 minichromosome maintenance complex component 2
MSH2 mutS homolog 2
PTEN phosphatase and tensin homolog
SMAD4 SMAD family member 4
STK11 serine/threonine kinase 11
TP53 tumor protein p53