columnar/cuboidal epithelial cell differentiation Gene Set

Dataset	GO Biological Process Annotations 2025
Category	structural or functional annotations
Type	biological process
Description	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube. (Gene Ontology, GO_0002065)
External Link	http://amigo.geneontology.org/amigo/term/GO:0002065
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Genes

18 genes participating in the columnar/cuboidal epithelial cell differentiation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol	Name
CCNO	cyclin O
CDX2	caudal type homeobox 2
DEUP1	deuterosome assembly protein 1
E2F4	E2F transcription factor 4, p107/p130-binding
ENAM	enamelin
FGF8	fibroblast growth factor 8 (androgen-induced)
GATA4	GATA binding protein 4
GATA5	GATA binding protein 5
GATA6	GATA binding protein 6
MCIDAS	multiciliate differentiation and DNA synthesis associated cell cycle protein
NPY	neuropeptide Y
NTF4	neurotrophin 4
PKP1	plakophilin 1
PYY	peptide YY
ROS1	ROS proto-oncogene 1 , receptor tyrosine kinase
SOX11	SRY (sex determining region Y)-box 11
SOX4	SRY (sex determining region Y)-box 4
TJP1	tight junction protein 1