common cold Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An upper respiratory tract disease which involves inflammation of the mucous membranes of the nose, throat, eyes, and eustachian tubes with watery then purulent discharge. This is an acute contagious disease caused by rhinoviruses, human parainfluenza viruses, human respiratory syncytial virus, influenza viruses, adenoviruses, enteroviruses, or metapneumovirus. (Human Disease Ontology, DOID_10459)
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Genes

274 genes co-occuring with the disease common cold in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
RNASE3 ribonuclease, RNase A family, 3 1.51325
TAS2R38 taste receptor, type 2, member 38 1.27737
IL5 interleukin 5 1.23994
SCGB1D4 secretoglobin, family 1D, member 4 1.20353
MUC5B mucin 5B, oligomeric mucus/gel-forming 1.17679
LTC4S leukotriene C4 synthase 1.12825
AOAH acyloxyacyl hydrolase (neutrophil) 1.10846
IL1B interleukin 1, beta 1.1051
PTGDR2 prostaglandin D2 receptor 2 1.10343
ICAM1 intercellular adhesion molecule 1 1.08495
KRTAP1-1 keratin associated protein 1-1 1.08202
KRTAP1-3 keratin associated protein 1-3 1.08202
TAS2R4 taste receptor, type 2, member 4 1.06564
TAS2R13 taste receptor, type 2, member 13 1.0606
TSLP thymic stromal lymphopoietin 1.06018
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 1.02903
TAS2R20 taste receptor, type 2, member 20 1.01891
MPO myeloperoxidase 1.01216
RARS arginyl-tRNA synthetase 0.994017
BPIFA1 BPI fold containing family A, member 1 0.987271
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.962053
CXCL8 chemokine (C-X-C motif) ligand 8 0.953273
CD79A CD79a molecule, immunoglobulin-associated alpha 0.952856
CHIA chitinase, acidic 0.950769
AQP12B aquaporin 12B 0.947019
FLNC filamin C, gamma 0.937459
SCGB1C1 secretoglobin, family 1C, member 1 0.937044
TLR9 toll-like receptor 9 0.904442
MMP9 matrix metallopeptidase 9 0.901567
CD4 CD4 molecule 0.881472
TTLL1 tubulin tyrosine ligase-like family member 1 0.874919
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 0.870825
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.869596
TNF tumor necrosis factor 0.858952
TAS2R30 taste receptor, type 2, member 30 0.849945
IL4 interleukin 4 0.843802
GATA3 GATA binding protein 3 0.841753
TIMP1 TIMP metallopeptidase inhibitor 1 0.840115
CYSLTR2 cysteinyl leukotriene receptor 2 0.838885
DEFB4A defensin, beta 4A 0.831918
CCL11 chemokine (C-C motif) ligand 11 0.826178
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.822897
PLA2G2E phospholipase A2, group IIE 0.818385
TLR3 toll-like receptor 3 0.815924
MARVELD2 MARVEL domain containing 2 0.806077
IL22RA1 interleukin 22 receptor, alpha 1 0.795411
TGFB1 transforming growth factor, beta 1 0.773296
TAS2R14 taste receptor, type 2, member 14 0.770844
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.766759
CYSLTR1 cysteinyl leukotriene receptor 1 0.763902
TLR2 toll-like receptor 2 0.763902
ERH enhancer of rudimentary homolog (Drosophila) 0.745578
CCL28 chemokine (C-C motif) ligand 28 0.745172
MUC7 mucin 7, secreted 0.744766
MMP2 matrix metallopeptidase 2 0.74436
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 0.737865
NFAM1 NFAT activating protein with ITAM motif 1 0.726929
DCXR dicarbonyl/L-xylulose reductase 0.724098
FOXP3 forkhead box P3 0.722077
MRC1 mannose receptor, C type 1 0.715215
DNAH1 dynein, axonemal, heavy chain 1 0.690293
LTF lactotransferrin 0.687091
POSTN periostin, osteoblast specific factor 0.683493
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.6791
CD68 CD68 molecule 0.677105
CXCL5 chemokine (C-X-C motif) ligand 5 0.667152
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing 0.664372
NPTXR neuronal pentraxin receptor 0.660404
CCL8 chemokine (C-C motif) ligand 8 0.65565
ZRANB2 zinc finger, RAN-binding domain containing 2 0.641827
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.641827
PNOC prepronociceptin 0.632384
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.631991
ADGRE3 adhesion G protein-coupled receptor E3 0.628065
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.627672
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.626103
ALOX5 arachidonate 5-lipoxygenase 0.6214
AQP12A aquaporin 12A 0.620226
PI4KB phosphatidylinositol 4-kinase, catalytic, beta 0.616703
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.615138
TLR4 toll-like receptor 4 0.608104
PDSS1 prenyl (decaprenyl) diphosphate synthase, subunit 1 0.606543
CD209 CD209 molecule 0.587444
SCYL1 SCY1-like 1 (S. cerevisiae) 0.58433
DNASE1 deoxyribonuclease I 0.579661
TLR7 toll-like receptor 7 0.56722
IL6 interleukin 6 0.557897
ACCS 1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional) 0.556344
CXCL10 chemokine (C-X-C motif) ligand 10 0.548583
EPX eosinophil peroxidase 0.547807
OCLN occludin 0.545093
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.533088
LYZ lysozyme 0.532701
IL17RD interleukin 17 receptor D 0.530381
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.529994
NPS neuropeptide S 0.528835
AQP5 aquaporin 5 0.528063
S100A7 S100 calcium binding protein A7 0.51919
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.511496
MMP7 matrix metallopeptidase 7 0.509192
HTRA3 HtrA serine peptidase 3 0.508808
FLNA filamin A, alpha 0.505739
CXCL13 chemokine (C-X-C motif) ligand 13 0.499997
PDCD1LG2 programmed cell death 1 ligand 2 0.498085
IL32 interleukin 32 0.494648
OXR1 oxidation resistance 1 0.493503
VAT1 vesicle amine transport 1 0.491215
CRP C-reactive protein, pentraxin-related 0.490454
HMGB1 high mobility group box 1 0.488549
CXCL6 chemokine (C-X-C motif) ligand 6 0.47753
MYD88 myeloid differentiation primary response 88 0.477151
ALB albumin 0.471846
FPR3 formyl peptide receptor 3 0.468441
IL33R interleukin 33 receptor 0.468063
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.467306
VLDLR very low density lipoprotein receptor 0.463905
CAND1 cullin-associated and neddylation-dissociated 1 0.462394
AQP11 aquaporin 11 0.461261
RYBP RING1 and YY1 binding protein 0.459373
CCL26 chemokine (C-C motif) ligand 26 0.454847
ELANE elastase, neutrophil expressed 0.454093
TTL tubulin tyrosine ligase 0.453716
TDP2 tyrosyl-DNA phosphodiesterase 2 0.446558
CD8A CD8a molecule 0.446182
NPW neuropeptide W 0.445429
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.445052
ARHGAP26 Rho GTPase activating protein 26 0.44129
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.437154
CLDN1 claudin 1 0.434899
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.434148
SCGB1D2 secretoglobin, family 1D, member 2 0.431519
RORC RAR-related orphan receptor C 0.424014
HPGDS hematopoietic prostaglandin D synthase 0.42139
CLDN7 claudin 7 0.42139
CCL5 chemokine (C-C motif) ligand 5 0.419892
CPA3 carboxypeptidase A3 (mast cell) 0.415773
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 0.415024
IRAK4 interleukin-1 receptor-associated kinase 4 0.410535
CCL24 chemokine (C-C motif) ligand 24 0.405678
OLFML3 olfactomedin-like 3 0.404557
LAMB1 laminin, beta 1 0.399334
ZCCHC7 zinc finger, CCHC domain containing 7 0.394863
SIGLEC8 sialic acid binding Ig-like lectin 8 0.394491
IDO1 indoleamine 2,3-dioxygenase 1 0.393374
MMP1 matrix metallopeptidase 1 0.385936
CD163 CD163 molecule 0.385193
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.382223
ADGRE1 adhesion G protein-coupled receptor E1 0.380739
FBXO11 F-box protein 11 0.379626
TBX21 T-box 21 0.378143
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.375179
MUC4 mucin 4, cell surface associated 0.371477
EBI3 Epstein-Barr virus induced 3 0.368888
CPA4 carboxypeptidase A4 0.363347
CAMP cathelicidin antimicrobial peptide 0.362609
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 0.356709
BET1 Bet1 golgi vesicular membrane trafficking protein 0.354499
SPINK5 serine peptidase inhibitor, Kazal type 5 0.353027
DMBT1 deleted in malignant brain tumors 1 0.351187
RAG1 recombination activating gene 1 0.347879
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.346042
FPR2 formyl peptide receptor 2 0.340906
SYK spleen tyrosine kinase 0.337608
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 0.337242
CLC Charcot-Leyden crystal galectin 0.335778
MMP8 matrix metallopeptidase 8 0.334681
PCBP2 poly(rC) binding protein 2 0.332487
TRPM5 transient receptor potential cation channel, subfamily M, member 5 0.332121
SCGB3A2 secretoglobin, family 3A, member 2 0.32993
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.324823
DEFB103A defensin, beta 103A 0.32373
IL17RB interleukin 17 receptor B 0.319363
TIMP4 TIMP metallopeptidase inhibitor 4 0.317545
IL33 interleukin 33 0.312464
SELL selectin L 0.308842
PRTN3 proteinase 3 0.308118
CCL20 chemokine (C-C motif) ligand 20 0.304142
YBX2 Y box binding protein 2 0.300894
TBXA2R thromboxane A2 receptor 0.297291
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.297291
RXRB retinoid X receptor, beta 0.297291
EYA4 EYA transcriptional coactivator and phosphatase 4 0.297291
PDZD4 PDZ domain containing 4 0.296211
OAZ1 ornithine decarboxylase antizyme 1 0.296211
MUC2 mucin 2, oligomeric mucus/gel-forming 0.292975
ANO1 anoctamin 1, calcium activated chloride channel 0.288668
DEFB103B defensin, beta 103B 0.286519
IL17A interleukin 17A 0.285802
SCGB3A1 secretoglobin, family 3A, member 1 0.284013
IL1A interleukin 1, alpha 0.283655
GNAT3 guanine nucleotide binding protein, alpha transducing 3 0.282582
AQP3 aquaporin 3 (Gill blood group) 0.275445
IFNL2 interferon, lambda 2 0.273664
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.272597
RPLP0 ribosomal protein, large, P0 0.27153
IL22 interleukin 22 0.271174
CCL23 chemokine (C-C motif) ligand 23 0.271174
TSC22D3 TSC22 domain family, member 3 0.269398
EPRS glutamyl-prolyl-tRNA synthetase 0.268687
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.268332
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.265494
TARBP2 TAR (HIV-1) RNA binding protein 2 0.264431
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.263722
POMC proopiomelanocortin 0.263368
NCF2 neutrophil cytosolic factor 2 0.25877
IL13RA1 interleukin 13 receptor, alpha 1 0.254888
CCL2 chemokine (C-C motif) ligand 2 0.254183
SCGB1D1 secretoglobin, family 1D, member 1 0.253831
CCR3 chemokine (C-C motif) receptor 3 0.251015
LDLR low density lipoprotein receptor 0.250663
PDZD11 PDZ domain containing 11 0.248905
PFAS phosphoribosylformylglycinamidine synthase 0.247852
SCGB2A1 secretoglobin, family 2A, member 1 0.244345
SLPI secretory leukocyte peptidase inhibitor 0.243645
IFNA1 interferon, alpha 1 0.241895
IL17C interleukin 17C 0.241196
CELA2A chymotrypsin-like elastase family, member 2A 0.241196
PPP1R9B protein phosphatase 1, regulatory subunit 9B 0.240148
SOCS3 suppressor of cytokine signaling 3 0.239799
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.238054
DNAI1 dynein, axonemal, intermediate chain 1 0.237357
IL13 interleukin 13 0.235268
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 0.23492
IFITM3 interferon induced transmembrane protein 3 0.229716
BMP3 bone morphogenetic protein 3 0.228679
FRMD6 FERM domain containing 6 0.223165
KRT84 keratin 84, type II 0.221108
BMP5 bone morphogenetic protein 5 0.221108
LGALS7B lectin, galactoside-binding, soluble, 7B 0.214636
NCAM1 neural cell adhesion molecule 1 0.207245
AQP7 aquaporin 7 0.201962
NELFCD negative elongation factor complex member C/D 0.197742
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.19742
CDSN corneodesmosin 0.197099
TJP1 tight junction protein 1 0.193915
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide 0.192657
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide 0.192344
LY96 lymphocyte antigen 96 0.192031
DNAH5 dynein, axonemal, heavy chain 5 0.189859
NAAA N-acylethanolamine acid amidase 0.189859
CD1C CD1c molecule 0.189244
ZFYVE9 zinc finger, FYVE domain containing 9 0.188632
NRP1 neuropilin 1 0.188326
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta 0.188022
NT5C2 5'-nucleotidase, cytosolic II 0.187113
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.180367
SCGB2A2 secretoglobin, family 2A, member 2 0.178682
CLCA4 chloride channel accessory 4 0.176215
USP9X ubiquitin specific peptidase 9, X-linked 0.176215
SCRT1 scratch family zinc finger 1 0.175679
CXCL9 chemokine (C-X-C motif) ligand 9 0.174881
PTGES prostaglandin E synthase 0.173832
CCL25 chemokine (C-C motif) ligand 25 0.173571
AICDA activation-induced cytidine deaminase 0.172038
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.168381
SOAT1 sterol O-acyltransferase 1 0.167452
CFP complement factor properdin 0.167452
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.167224
ACAT1 acetyl-CoA acetyltransferase 1 0.167224
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B 0.166768
CD248 CD248 molecule, endosialin 0.166095
NGDN neuroguidin, EIF4E binding protein 0.166095
IGH immunoglobulin heavy locus 0.165874
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.164786
GM2A GM2 ganglioside activator 0.164571
SFTPA1 surfactant protein A1 0.164149
TFRC transferrin receptor 0.163938
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.162109
MAZ MYC-associated zinc finger protein (purine-binding transcription factor) 0.162109
CNTLN centlein, centrosomal protein 0.160761
SPP1 secreted phosphoprotein 1 0.15948
BMP1 bone morphogenetic protein 1 0.159302
CXCR3 chemokine (C-X-C motif) receptor 3 0.158097
TAPBP TAP binding protein (tapasin) 0.157765