complete lethality Gene Set
Genes
18 gene mutations causing the complete lethality phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.
| Symbol |
Name |
|
ASXL1
|
additional sex combs like transcriptional regulator 1
|
|
CLP1
|
cleavage and polyadenylation factor I subunit 1
|
|
FBXW7
|
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
|
|
GNAO1
|
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
|
INSM1
|
insulinoma-associated 1
|
|
ITGB1
|
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
|
|
MECOM
|
MDS1 and EVI1 complex locus
|
|
OCA2
|
oculocutaneous albinism II
|
|
PFN1
|
profilin 1
|
|
PICALM
|
phosphatidylinositol binding clathrin assembly protein
|
|
PLK3
|
polo-like kinase 3
|
|
PRPS1
|
phosphoribosyl pyrophosphate synthetase 1
|
|
RUVBL2
|
RuvB-like AAA ATPase 2
|
|
SFPQ
|
splicing factor proline/glutamine-rich
|
|
T
|
T, brachyury homolog (mouse)
|
|
TCF7L2
|
transcription factor 7-like 2 (T-cell specific, HMG-box)
|
|
VANGL2
|
VANGL planar cell polarity protein 2
|
