complicated Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

159 genes co-occuring with the biological term complicated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ADARB1 adenosine deaminase, RNA-specific, B1
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA2A adenosine A2a receptor
AGER advanced glycosylation end product-specific receptor
AGTR1 angiotensin II receptor, type 1
ANGPT2 angiopoietin 2
AOC3 amine oxidase, copper containing 3
APC adenomatous polyposis coli
APOC2 apolipoprotein C-II
APOE apolipoprotein E
ATL1 atlastin GTPase 1
BDNF brain-derived neurotrophic factor
CALR calreticulin
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CCND1 cyclin D1
CD209 CD209 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CETP cholesteryl ester transfer protein, plasma
CHIT1 chitinase 1 (chitotriosidase)
CLCA1 chloride channel accessory 1
CRP C-reactive protein, pentraxin-related
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDHD2 DDHD domain containing 2
DLK1 delta-like 1 homolog (Drosophila)
ENG endoglin
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2R coagulation factor II (thrombin) receptor
FA2H fatty acid 2-hydroxylase
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FLG filaggrin
FLT1 fms-related tyrosine kinase 1
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FTL ferritin, light polypeptide
GATA3 GATA binding protein 3
GBA2 glucosidase, beta (bile acid) 2
GH1 growth hormone 1
GNA14 guanine nucleotide binding protein (G protein), alpha 14
H19 H19, imprinted maternally expressed transcript (non-protein coding)
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HBA2 hemoglobin, alpha 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HNF4A hepatocyte nuclear factor 4, alpha
HRH4 histamine receptor H4
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HTRA1 HtrA serine peptidase 1
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
IL10 interleukin 10
IL12A interleukin 12A
IL12B interleukin 12B
IL18 interleukin 18
IL2 interleukin 2
IL5 interleukin 5
IL6R interleukin 6 receptor
INF2 inverted formin, FH2 and WH2 domain containing
INS insulin
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KDM2A lysine (K)-specific demethylase 2A
KDR kinase insert domain receptor
KIF5A kinesin family member 5A
KRT9 keratin 9, type I
LBP lipopolysaccharide binding protein
LDHA lactate dehydrogenase A
LEPR leptin receptor
LPA lipoprotein, Lp(a)
LPL lipoprotein lipase
MAGEA3 melanoma antigen family A3
MAGEA4 melanoma antigen family A4
MAOA monoamine oxidase A
MIR155 microRNA 155
MIR424 microRNA 424
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP26 matrix metallopeptidase 26
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
NCF4 neutrophil cytosolic factor 4, 40kDa
ND1
NDRG1 N-myc downstream regulated 1
NIPA1 non imprinted in Prader-Willi/Angelman syndrome 1
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH3 notch 3
NPC1 Niemann-Pick disease, type C1
NPPB natriuretic peptide B
NR1H3 nuclear receptor subfamily 1, group H, member 3
OPA1 optic atrophy 1 (autosomal dominant)
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PGF placental growth factor
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PMP22 peripheral myelin protein 22
PNPLA3 patatin-like phospholipase domain containing 3
PROS1 protein S (alpha)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBP4 retinol binding protein 4, plasma
SAA1 serum amyloid A1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN2A sodium channel, voltage gated, type II alpha subunit
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SGCE sarcoglycan, epsilon
SHBG sex hormone-binding globulin
SIAE sialic acid acetylesterase
SIRT3 sirtuin 3
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SPAST spastin
SPG11 spastic paraplegia 11 (autosomal recessive)
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive)
SSTR2 somatostatin receptor 2
STOX1 storkhead box 1
STOX2 storkhead box 2
TEX101 testis expressed 101
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TK1 thymidine kinase 1, soluble
TLR1 toll-like receptor 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF18 tumor necrosis factor receptor superfamily, member 18
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TREM1 triggering receptor expressed on myeloid cells 1
TSPY1 testis specific protein, Y-linked 1
UBQLN2 ubiquilin 2
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
ZFYVE26 zinc finger, FYVE domain containing 26