conessine-2135 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the conessine-2135 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ACTN2 actinin, alpha 2
ADARB1 adenosine deaminase, RNA-specific, B1
ADD2 adducin 2 (beta)
ADORA1 adenosine A1 receptor
ALOXE3 arachidonate lipoxygenase 3
APOE apolipoprotein E
AQP1 aquaporin 1 (Colton blood group)
ARMC9 armadillo repeat containing 9
ATP13A2 ATPase type 13A2
BIN1 bridging integrator 1
BMP2 bone morphogenetic protein 2
C22ORF31 chromosome 22 open reading frame 31
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CASP2 caspase 2, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CLCA1 chloride channel accessory 1
CLEC16A C-type lectin domain family 16, member A
CNGB3 cyclic nucleotide gated channel beta 3
COL4A1 collagen, type IV, alpha 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTSZ cathepsin Z
CTTN cortactin
DDAH2 dimethylarginine dimethylaminohydrolase 2
DIAPH2 diaphanous-related formin 2
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK6 dedicator of cytokinesis 6
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EFNA5 ephrin-A5
EPS8L1 EPS8-like 1
FAM127B family with sequence similarity 127, member B
FOXG1 forkhead box G1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GK2 glycerol kinase 2
GPR137 G protein-coupled receptor 137
GPR20 G protein-coupled receptor 20
GRPR gastrin-releasing peptide receptor
GSK3A glycogen synthase kinase 3 alpha
IFNA14 interferon, alpha 14
IQCK IQ motif containing K
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNC2 potassium channel, voltage gated Shaw related subfamily C, member 2
KIR2DL5A killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
KLF12 Kruppel-like factor 12
KRT24 keratin 24, type I
KRT6B keratin 6B, type II
LILRA6 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
LINC00652 long intergenic non-protein coding RNA 652
LOC100130331 POTE ankyrin domain family, member F pseudogene
MAGEA4 melanoma antigen family A4
MARCKS myristoylated alanine-rich protein kinase C substrate
MFAP3 microfibrillar-associated protein 3
MORN1 MORN repeat containing 1
MVP major vault protein
MYL4 myosin, light chain 4, alkali; atrial, embryonic
MYO1B myosin IB
MYOF myoferlin
NABP1 nucleic acid binding protein 1
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NIPAL2 NIPA-like domain containing 2
NMT2 N-myristoyltransferase 2
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NPEPL1 aminopeptidase-like 1
OR10J1 olfactory receptor, family 10, subfamily J, member 1
PEX6 peroxisomal biogenesis factor 6
PIAS4 protein inhibitor of activated STAT, 4
PLK3 polo-like kinase 3
PRB1 proline-rich protein BstNI subfamily 1
PTPRM protein tyrosine phosphatase, receptor type, M
PYCRL pyrroline-5-carboxylate reductase-like
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RIMS2 regulating synaptic membrane exocytosis 2
RPS4Y1 ribosomal protein S4, Y-linked 1
SCAND2P SCAN domain containing 2 pseudogene
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SFRP4 secreted frizzled-related protein 4
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SP110 SP110 nuclear body protein
SRSF5 serine/arginine-rich splicing factor 5
STAC SH3 and cysteine rich domain
STS steroid sulfatase (microsomal), isozyme S
SYNE2 spectrin repeat containing, nuclear envelope 2
TAPT1 transmembrane anterior posterior transformation 1
TCF3 transcription factor 3
THAP10 THAP domain containing 10
THRB thyroid hormone receptor, beta
TP63 tumor protein p63
TRAF1 TNF receptor-associated factor 1
TRIM2 tripartite motif containing 2
UBOX5 U-box domain containing 5
VPRBP Vpr (HIV-1) binding protein
VPS13B vacuolar protein sorting 13 homolog B (yeast)
VSNL1 visinin-like 1
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZER1 zyg-11 related, cell cycle regulator
ZNF235 zinc finger protein 235

decreased expression

Symbol Name
ACAD10 acyl-CoA dehydrogenase family, member 10
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACPP acid phosphatase, prostate
ADAM15 ADAM metallopeptidase domain 15
AHCTF1 AT hook containing transcription factor 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APH1B APH1B gamma secretase subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ATG9A autophagy related 9A
BNC2 basonuclin 2
BTBD18 BTB (POZ) domain containing 18
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CA5BP1 carbonic anhydrase VB pseudogene 1
CCDC186 coiled-coil domain containing 186
CCDC25 coiled-coil domain containing 25
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DKK2 dickkopf WNT signaling pathway inhibitor 2
DNMBP dynamin binding protein
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
ERN2 endoplasmic reticulum to nucleus signaling 2
FCF1 FCF1 rRNA-processing protein
GATAD2A GATA zinc finger domain containing 2A
GCH1 GTP cyclohydrolase 1
GEMIN8 gem (nuclear organelle) associated protein 8
GNA12 guanine nucleotide binding protein (G protein) alpha 12
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HECTD3 HECT domain containing E3 ubiquitin protein ligase 3
HIST1H2AM histone cluster 1, H2am
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IL18 interleukin 18
JUP junction plakoglobin
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAGEH1 melanoma antigen family H1
MAPK3 mitogen-activated protein kinase 3
MBTD1 mbt domain containing 1
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL10 nucleolar protein 10
PHC1 polyhomeotic homolog 1 (Drosophila)
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PNOC prepronociceptin
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPDPF pancreatic progenitor cell differentiation and proliferation factor
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR7 proline rich 7 (synaptic)
PSKH1 protein serine kinase H1
PTGES2 prostaglandin E synthase 2
RAB5B RAB5B, member RAS oncogene family
RNF31 ring finger protein 31
SERTAD3 SERTA domain containing 3
SH2D3C SH2 domain containing 3C
SHARPIN SHANK-associated RH domain interactor
SIL1 SIL1 nucleotide exchange factor
SLC10A3 solute carrier family 10, member 3
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLPI secretory leukocyte peptidase inhibitor
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMYD5 SMYD family member 5
SNAI1 snail family zinc finger 1
SNIP1 Smad nuclear interacting protein 1
SNX29P2 sorting nexin 29 pseudogene 2
STARD8 StAR-related lipid transfer (START) domain containing 8
STAT5A signal transducer and activator of transcription 5A
STX1A syntaxin 1A (brain)
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
SURF2 surfeit 2
TEC tec protein tyrosine kinase
TGFBR1 transforming growth factor, beta receptor 1
THRAP3 thyroid hormone receptor associated protein 3
TLR8 toll-like receptor 8
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMBIM1 transmembrane BAX inhibitor motif containing 1
TMEM120B transmembrane protein 120B
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TRAIP TRAF interacting protein
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSSC4 tumor suppressing subtransferable candidate 4
TUBA3C tubulin, alpha 3c
WNT10B wingless-type MMTV integration site family, member 10B
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZBTB6 zinc finger and BTB domain containing 6
ZC3H12A zinc finger CCCH-type containing 12A
ZNF223 zinc finger protein 223
ZNF747 zinc finger protein 747