conessine-2792 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the conessine-2792 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM22 ADAM metallopeptidase domain 22
AHSG alpha-2-HS-glycoprotein
ALS2CL ALS2 C-terminal like
ANO2 anoctamin 2, calcium activated chloride channel
AR androgen receptor
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ART1 ADP-ribosyltransferase 1
BCO1 beta-carotene oxygenase 1
CACYBP calcyclin binding protein
CALCOCO1 calcium binding and coiled-coil domain 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CCDC40 coiled-coil domain containing 40
CD34 CD34 molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CDK13 cyclin-dependent kinase 13
CNTNAP2 contactin associated protein-like 2
COL1A1 collagen, type I, alpha 1
CPQ carboxypeptidase Q
CRIP1 cysteine-rich protein 1 (intestinal)
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DESI2 desumoylating isopeptidase 2
DICER1 dicer 1, ribonuclease type III
DPY19L1P1 DPY19L1 pseudogene 1
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOSC2 exosome component 2
FAM186A family with sequence similarity 186, member A
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FFAR2 free fatty acid receptor 2
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GADD45G growth arrest and DNA-damage-inducible, gamma
GLRA1 glycine receptor, alpha 1
GMPR guanosine monophosphate reductase
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
HCRP1 hepatocellular carcinoma-related HCRP1
HFE hemochromatosis
HOXB2 homeobox B2
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HUS1 HUS1 checkpoint homolog (S. pombe)
ICA1 islet cell autoantigen 1, 69kDa
ITM2C integral membrane protein 2C
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JADE2 jade family PHD finger 2
KANK1 KN motif and ankyrin repeat domains 1
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIAA0368 KIAA0368
KIAA1107 KIAA1107
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LAMP1 lysosomal-associated membrane protein 1
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MAGOH2P mago-nashi homolog 2, pseudogene
MIOS missing oocyte, meiosis regulator, homolog (Drosophila)
N4BP3 NEDD4 binding protein 3
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NMT2 N-myristoyltransferase 2
NOTCH4 notch 4
NPIPB3 nuclear pore complex interacting protein family, member B3
NT5M 5',3'-nucleotidase, mitochondrial
NXPH4 neurexophilin 4
PACS1 phosphofurin acidic cluster sorting protein 1
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PEX16 peroxisomal biogenesis factor 16
PGBD5 piggyBac transposable element derived 5
PITX1 paired-like homeodomain 1
PLAU plasminogen activator, urokinase
PLK3 polo-like kinase 3
PLLP plasmolipin
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP5C protein phosphatase 5, catalytic subunit
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PTRF polymerase I and transcript release factor
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RAB6B RAB6B, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RBM5 RNA binding motif protein 5
RECQL5 RecQ protein-like 5
RFPL1S RFPL1 antisense RNA 1
RGS12 regulator of G-protein signaling 12
RHBG Rh family, B glycoprotein (gene/pseudogene)
SAMD4A sterile alpha motif domain containing 4A
SIDT1 SID1 transmembrane family, member 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC16A4 solute carrier family 16, member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOAT2 sterol O-acyltransferase 2
SPATA5L1 spermatogenesis associated 5-like 1
SUN1 Sad1 and UNC84 domain containing 1
TFIP11 tuftelin interacting protein 11
TJAP1 tight junction associated protein 1 (peripheral)
TRIO trio Rho guanine nucleotide exchange factor
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ADM adrenomedullin
AKAP5 A kinase (PRKA) anchor protein 5
ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARMC4 armadillo repeat containing 4
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BMP10 bone morphogenetic protein 10
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHKB choline kinase beta
CNGB3 cyclic nucleotide gated channel beta 3
COPS7B COP9 signalosome subunit 7B
COPZ2 coatomer protein complex, subunit zeta 2
CORT cortistatin
CSF1R colony stimulating factor 1 receptor
CTNNBIP1 catenin, beta interacting protein 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DGKE diacylglycerol kinase, epsilon 64kDa
DNALI1 dynein, axonemal, light intermediate chain 1
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EHBP1L1 EH domain binding protein 1-like 1
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPPK1 epiplakin 1
FAM189A2 family with sequence similarity 189, member A2
FAM63A family with sequence similarity 63, member A
FBXL7 F-box and leucine-rich repeat protein 7
FBXO46 F-box protein 46
FLT4 fms-related tyrosine kinase 4
FRAS1 Fraser extracellular matrix complex subunit 1
GAMT guanidinoacetate N-methyltransferase
GLB1L2 galactosidase, beta 1-like 2
GSTTP1 glutathione S-transferase theta pseudogene 1
HDAC5 histone deacetylase 5
HIST1H3B histone cluster 1, H3b
IGSF1 immunoglobulin superfamily, member 1
INPP5J inositol polyphosphate-5-phosphatase J
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KREMEN2 kringle containing transmembrane protein 2
LMO2 LIM domain only 2 (rhombotin-like 1)
LOC257152 uncharacterized LOC257152
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRPL41 mitochondrial ribosomal protein L41
MRPS18C mitochondrial ribosomal protein S18C
MUC3A mucin 3A, cell surface associated
MXD3 MAX dimerization protein 3
MYO1E myosin IE
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRSN2 neurensin 2
NSD1 nuclear receptor binding SET domain protein 1
PC pyruvate carboxylase
PGPEP1 pyroglutamyl-peptidase I
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G10 phospholipase A2, group X
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PNPLA6 patatin-like phospholipase domain containing 6
PPT2 palmitoyl-protein thioesterase 2
PRICKLE3 prickle homolog 3 (Drosophila)
PTDSS2 phosphatidylserine synthase 2
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RGS19 regulator of G-protein signaling 19
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RIN2 Ras and Rab interactor 2
RNF122 ring finger protein 122
RNF126P1 ring finger protein 126 pseudogene 1
SAYSD1 SAYSVFN motif domain containing 1
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
TCTN2 tectonic family member 2
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM121 transmembrane protein 121
TMEM209 transmembrane protein 209
TMEM51 transmembrane protein 51
TMLHE trimethyllysine hydroxylase, epsilon
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TPK1 thiamin pyrophosphokinase 1
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
USP19 ubiquitin specific peptidase 19
VAV1 vav 1 guanine nucleotide exchange factor
VWA1 von Willebrand factor A domain containing 1
WDR60 WD repeat domain 60
WDR91 WD repeat domain 91
ZMAT5 zinc finger, matrin-type 5
ZNF282 zinc finger protein 282
ZNF804A zinc finger protein 804A
ZNF862 zinc finger protein 862