| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/151171 |
| Similar Terms | |
| Downloads & Tools |
199 proteins with high or low expression in conivaptan relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ABHD4 | abhydrolase domain containing 4 | 1.07 |
| MXRA7 | matrix-remodelling associated 7 | 0.81 |
| TRIB3 | tribbles pseudokinase 3 | 0.79 |
| RNF166 | ring finger protein 166 | 0.77 |
| PEX19 | peroxisomal biogenesis factor 19 | 0.74 |
| MED29 | mediator complex subunit 29 | 0.72 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.71 |
| BID | BH3 interacting domain death agonist | 0.7 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.69 |
| SLC49A4 | solute carrier family 49 member 4 | 0.69 |
| NUP62 | nucleoporin 62kDa | 0.67 |
| UBQLN1 | ubiquilin 1 | 0.64 |
| TSPAN3 | tetraspanin 3 | 0.64 |
| UBQLN2 | ubiquilin 2 | 0.64 |
| DOHH | deoxyhypusine hydroxylase/monooxygenase | 0.64 |
| YAP1 | Yes-associated protein 1 | 0.63 |
| IKBKG | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma | 0.62 |
| NHP2 | NHP2 ribonucleoprotein | 0.61 |
| IFI30 | interferon, gamma-inducible protein 30 | 0.6 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) | 0.59 |
| WDR5B | WD repeat domain 5B | 0.59 |
| JPT1 | Jupiter microtubule associated homolog 1 | 0.59 |
| NUCB1 | nucleobindin 1 | 0.59 |
| HSP90AB3P | heat shock protein 90kDa alpha (cytosolic), class B member 3, pseudogene | 0.58 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | 0.58 |
| FAR1 | fatty acyl CoA reductase 1 | 0.55 |
| LSM3 | LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.55 |
| TMEM104 | transmembrane protein 104 | 0.54 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.54 |
| KSR1 | kinase suppressor of ras 1 | 0.54 |
| UPP1 | uridine phosphorylase 1 | 0.53 |
| DCTN2 | dynactin 2 (p50) | 0.53 |
| RPLP1 | ribosomal protein, large, P1 | 0.53 |
| CLTB | clathrin, light chain B | 0.52 |
| HMGN4 | high mobility group nucleosomal binding domain 4 | 0.52 |
| SKP1 | S-phase kinase-associated protein 1 | 0.52 |
| ISL2 | ISL LIM homeobox 2 | 0.52 |
| SRXN1 | sulfiredoxin 1 | 0.51 |
| RGS20 | regulator of G-protein signaling 20 | 0.51 |
| PLAU | plasminogen activator, urokinase | 0.51 |
| B3GALNT2 | beta-1,3-N-acetylgalactosaminyltransferase 2 | 0.51 |
| SAYSD1 | SAYSVFN motif domain containing 1 | 0.5 |
| AGTRAP | angiotensin II receptor-associated protein | 0.5 |
| NIBAN1 | niban apoptosis regulator 1 | 0.5 |
| HRH1 | histamine receptor H1 | 0.49 |
| NUCB2 | nucleobindin 2 | 0.49 |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow | 0.48 |
| NABP1 | nucleic acid binding protein 1 | 0.48 |
| SGTA | small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha | 0.48 |
| PLAUR | plasminogen activator, urokinase receptor | 0.48 |
| ZNF724 | zinc finger protein 724 | 0.48 |
| UBAP1 | ubiquitin associated protein 1 | 0.47 |
| HPS4 | Hermansky-Pudlak syndrome 4 | 0.47 |
| FAM241B | family with sequence similarity 241 member B | 0.46 |
| BCL2L12 | BCL2-like 12 (proline rich) | 0.46 |
| UQCRH | ubiquinol-cytochrome c reductase hinge protein | 0.46 |
| HGH1 | HGH1 homolog (S. cerevisiae) | 0.46 |
| CCN3 | cellular communication network factor 3 | 0.45 |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) | 0.45 |
| UCK1 | uridine-cytidine kinase 1 | 0.45 |
| STARD3NL | STARD3 N-terminal like | 0.45 |
| UBE2F | ubiquitin-conjugating enzyme E2F (putative) | 0.45 |
| FAM219A | family with sequence similarity 219, member A | 0.45 |
| FLYWCH1 | FLYWCH-type zinc finger 1 | 0.45 |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 | 0.44 |
| ZNF302 | zinc finger protein 302 | 0.44 |
| WASHC3 | WASH complex subunit 3 | 0.44 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.43 |
| SESN2 | sestrin 2 | 0.43 |
| ACVR2A | activin A receptor, type IIA | 0.42 |
| TBC1D20 | TBC1 domain family, member 20 | 0.42 |
| LIPT2 | lipoyl(octanoyl) transferase 2 (putative) | 0.42 |
| SLX4 | SLX4 structure-specific endonuclease subunit | 0.41 |
| TRIM13 | tripartite motif containing 13 | 0.41 |
| WWOX | WW domain containing oxidoreductase | 0.41 |
| PSEN2 | presenilin 2 | 0.41 |
| IGSF8 | immunoglobulin superfamily, member 8 | 0.41 |
| SYAP1 | synapse associated protein 1 | 0.41 |
| PWWP2B | PWWP domain containing 2B | 0.41 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.41 |
| CNEP1R1 | CTD nuclear envelope phosphatase 1 regulatory subunit 1 | 0.41 |
| AGPAT2 | 1-acylglycerol-3-phosphate O-acyltransferase 2 | 0.41 |
| TMEM98 | transmembrane protein 98 | 0.41 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.41 |
| PRELID3B | PRELI domain containing 3B | 0.4 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A | 0.4 |
| MT1X | metallothionein 1X | 0.4 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | 0.4 |
| PTMA | prothymosin, alpha | 0.4 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | 0.4 |
| ZXDC | ZXD family zinc finger C | 0.4 |
| H1-5 | H1.5 linker histone, cluster member | 0.39 |
| INAVA | innate immunity activator | 0.39 |
| STC2 | stanniocalcin 2 | 0.39 |
| ADIRF | adipogenesis regulatory factor | 0.39 |
| CD63 | CD63 molecule | 0.39 |
| NRP1 | neuropilin 1 | 0.39 |
| DSE | dermatan sulfate epimerase | 0.39 |
| MDM1 | Mdm1 nuclear protein homolog (mouse) | 0.39 |
| FAM110C | family with sequence similarity 110, member C | 0.39 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ALPK3 | alpha-kinase 3 | -2.85 |
| DNAH12 | dynein, axonemal, heavy chain 12 | -2.73 |
| C6ORF141 | chromosome 6 open reading frame 141 | -2.01 |
| PIP | prolactin-induced protein | -1.62 |
| C12ORF60 | chromosome 12 open reading frame 60 | -1.37 |
| FRMPD3 | FERM and PDZ domain containing 3 | -1.03 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) | -0.92 |
| MID2 | midline 2 | -0.77 |
| MKX | mohawk homeobox | -0.76 |
| POLE4 | polymerase (DNA-directed), epsilon 4, accessory subunit | -0.76 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | -0.75 |
| RNF5 | ring finger protein 5, E3 ubiquitin protein ligase | -0.71 |
| SLC4A11 | solute carrier family 4, sodium borate transporter, member 11 | -0.67 |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) | -0.62 |
| MKRN1 | makorin ring finger protein 1 | -0.58 |
| MTFR2 | mitochondrial fission regulator 2 | -0.56 |
| ZDHHC3 | zinc finger, DHHC-type containing 3 | -0.56 |
| PHYH | phytanoyl-CoA 2-hydroxylase | -0.55 |
| SYTL2 | synaptotagmin-like 2 | -0.53 |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs | -0.52 |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 | -0.51 |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 | -0.51 |
| CCAR2 | cell cycle and apoptosis regulator 2 | -0.51 |
| CAPN6 | calpain 6 | -0.49 |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 | -0.49 |
| DENND5A | DENN/MADD domain containing 5A | -0.48 |
| BAIAP2 | BAI1-associated protein 2 | -0.48 |
| LMOD1 | leiomodin 1 (smooth muscle) | -0.48 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | -0.47 |
| PPIE | peptidylprolyl isomerase E (cyclophilin E) | -0.47 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.47 |
| BHMT | betaine--homocysteine S-methyltransferase | -0.47 |
| PLA2G12A | phospholipase A2, group XIIA | -0.46 |
| AURKAIP1 | aurora kinase A interacting protein 1 | -0.44 |
| NIPSNAP3A | nipsnap homolog 3A (C. elegans) | -0.43 |
| PCMTD1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1 | -0.43 |
| LRRC45 | leucine rich repeat containing 45 | -0.41 |
| PIMREG | PICALM interacting mitotic regulator | -0.41 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.41 |
| CISD3 | CDGSH iron sulfur domain 3 | -0.41 |
| OGG1 | 8-oxoguanine DNA glycosylase | -0.4 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | -0.4 |
| DPYD | dihydropyrimidine dehydrogenase | -0.39 |
| STK25 | serine/threonine kinase 25 | -0.39 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.39 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.39 |
| POLR2M | polymerase (RNA) II (DNA directed) polypeptide M | -0.39 |
| TEAD2 | TEA domain family member 2 | -0.39 |
| S100A5 | S100 calcium binding protein A5 | -0.39 |
| TCTN2 | tectonic family member 2 | -0.38 |
| FEM1C | fem-1 homolog c (C. elegans) | -0.38 |
| ACTN3 | actinin, alpha 3 (gene/pseudogene) | -0.38 |
| SYTL3 | synaptotagmin-like 3 | -0.38 |
| ANKRD44 | ankyrin repeat domain 44 | -0.38 |
| TMEM131L | transmembrane 131 like | -0.38 |
| COX16 | COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) | -0.37 |
| ODC1 | ornithine decarboxylase 1 | -0.37 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) | -0.37 |
| METTL9 | methyltransferase like 9 | -0.37 |
| ANKRD36C | ankyrin repeat domain 36C | -0.37 |
| EVL | Enah/Vasp-like | -0.37 |
| TMEM246 | transmembrane protein 246 | -0.36 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.36 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B | -0.36 |
| AADAT | aminoadipate aminotransferase | -0.36 |
| LIN7A | lin-7 homolog A (C. elegans) | -0.35 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) | -0.35 |
| RLIM | ring finger protein, LIM domain interacting | -0.35 |
| MSL3 | male-specific lethal 3 homolog (Drosophila) | -0.35 |
| CEP68 | centrosomal protein 68kDa | -0.34 |
| DPYSL4 | dihydropyrimidinase-like 4 | -0.34 |
| SGK3 | serum/glucocorticoid regulated kinase family, member 3 | -0.34 |
| NMU | neuromedin U | -0.34 |
| METAP2 | methionyl aminopeptidase 2 | -0.34 |
| AXIN2 | axin 2 | -0.34 |
| SLX4IP | SLX4 interacting protein | -0.33 |
| CKS1B | CDC28 protein kinase regulatory subunit 1B | -0.33 |
| ALS2CL | ALS2 C-terminal like | -0.33 |
| OBSL1 | obscurin-like 1 | -0.33 |
| RILPL2 | Rab interacting lysosomal protein-like 2 | -0.33 |
| SORT1 | sortilin 1 | -0.33 |
| SFXN5 | sideroflexin 5 | -0.33 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.33 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like | -0.33 |
| SINHCAF | SIN3-HDAC complex associated factor | -0.32 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.32 |
| LIAS | lipoic acid synthetase | -0.32 |
| NEBL | nebulette | -0.32 |
| CPA4 | carboxypeptidase A4 | -0.32 |
| FAM89A | family with sequence similarity 89, member A | -0.32 |
| TAOK2 | TAO kinase 2 | -0.32 |
| GCH1 | GTP cyclohydrolase 1 | -0.32 |
| IPP | intracisternal A particle-promoted polypeptide | -0.31 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -0.31 |
| UBE2W | ubiquitin-conjugating enzyme E2W (putative) | -0.31 |
| BCORL1 | BCL6 corepressor-like 1 | -0.31 |
| NFYA | nuclear transcription factor Y, alpha | -0.31 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.31 |
| BDNF | brain-derived neurotrophic factor | -0.3 |
