conjunctivitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description Conjunctivitis is a conjunctival disease described as a inflammation of the conjunctiva, the outermost layer of the eye and the inner surface of the eyelids, which is most commonly due to an allergic reaction or an infection (usually viral, but sometimes bacterial. Fungal infections are rare and occur mainly in people who use corticosteroid eye drops for a long time or have eye injuries involving vegetable matter. Newborns are particularly susceptible to eye infections, which they acquire from organisms in the mother's birth canal (neonatal conjunctivitis. (Human Disease Ontology, DOID_6195)
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Genes

276 genes co-occuring with the disease conjunctivitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HRH1 histamine receptor H1 1.46144
PLG plasminogen 1.45616
CD79A CD79a molecule, immunoglobulin-associated alpha 1.35289
RNASE3 ribonuclease, RNase A family, 3 1.32061
CCL11 chemokine (C-C motif) ligand 11 1.10006
PHB2 prohibitin 2 0.988957
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 0.978426
LYZ lysozyme 0.976744
CD4 CD4 molecule 0.966244
MRAP melanocortin 2 receptor accessory protein 0.946603
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.942027
ALB albumin 0.933727
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.927932
EIF3K eukaryotic translation initiation factor 3, subunit K 0.907731
CMA1 chymase 1, mast cell 0.906909
GLYATL1 glycine-N-acyltransferase-like 1 0.902389
NLRP3 NLR family, pyrin domain containing 3 0.895
NBPF1 neuroblastoma breakpoint family, member 1 0.887208
LTF lactotransferrin 0.876557
ICAM1 intercellular adhesion molecule 1 0.865502
SOCS5 suppressor of cytokine signaling 5 0.859771
PFN4 profilin family, member 4 0.853631
LAX1 lymphocyte transmembrane adaptor 1 0.840115
DCXR dicarbonyl/L-xylulose reductase 0.818796
CRP C-reactive protein, pentraxin-related 0.806077
TSPO translocator protein (18kDa) 0.798692
IL4 interleukin 4 0.795002
PFN1 profilin 1 0.790492
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.789672
PFN2 profilin 2 0.781479
FUK fucokinase 0.779432
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.743141
CCR3 chemokine (C-C motif) receptor 3 0.728143
BTD biotinidase 0.707157
GPR135 G protein-coupled receptor 135 0.706754
CHIA chitinase, acidic 0.697911
IL1RN interleukin 1 receptor antagonist 0.690293
LAMB4 laminin, beta 4 0.65565
IGHE immunoglobulin heavy constant epsilon 0.646953
MXD3 MAX dimerization protein 3 0.643009
GPR32 G protein-coupled receptor 32 0.636708
SHE Src homology 2 domain containing E 0.624143
IL1B interleukin 1, beta 0.610838
OCA2 oculocutaneous albinism II 0.60342
TNF tumor necrosis factor 0.594843
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.592506
PLEK2 pleckstrin 2 0.585887
TSLP thymic stromal lymphopoietin 0.581996
FLNA filamin A, alpha 0.573828
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.568386
EPX eosinophil peroxidase 0.556344
HLA-C major histocompatibility complex, class I, C 0.550134
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.548583
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) 0.541217
PDC phosducin 0.535409
TMEM51 transmembrane protein 51 0.533088
WDR13 WD repeat domain 13 0.530768
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4 0.528449
SRCIN1 SRC kinase signaling inhibitor 1 0.51611
NVL nuclear VCP-like 0.513417
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.511496
PITX1 paired-like homeodomain 1 0.503058
DOCK11 dedicator of cytokinesis 11 0.491597
ALPPL2 alkaline phosphatase, placental-like 2 0.490072
HVCN1 hydrogen voltage gated channel 1 0.489691
ALPP alkaline phosphatase, placental 0.489691
ALPL alkaline phosphatase, liver/bone/kidney 0.489311
HSPG2 heparan sulfate proteoglycan 2 0.486646
SLPI secretory leukocyte peptidase inhibitor 0.478289
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.469954
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) 0.469954
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.465794
TLR3 toll-like receptor 3 0.459751
SAA2 serum amyloid A2 0.451831
MUC16 mucin 16, cell surface associated 0.428891
PRAMEF10 PRAME family member 10 0.42664
CXCL11 chemokine (C-X-C motif) ligand 11 0.42664
C3 complement component 3 0.426265
CD40 CD40 molecule, TNF receptor superfamily member 5 0.424765
SH3PXD2B SH3 and PX domains 2B 0.418394
SUMF2 sulfatase modifying factor 2 0.416147
CRLF2 cytokine receptor-like factor 2 0.412405
F2RL1 coagulation factor II (thrombin) receptor-like 1 0.409414
IL6 interleukin 6 0.408666
CATSPER1 cation channel, sperm associated 1 0.406425
SAG S-antigen; retina and pineal gland (arrestin) 0.398216
PDCL phosducin-like 0.394863
COL17A1 collagen, type XVII, alpha 1 0.384451
IL13 interleukin 13 0.377773
CAV2 caveolin 2 0.37555
VCAM1 vascular cell adhesion molecule 1 0.372958
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.369258
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta 0.368888
IFI44L interferon-induced protein 44-like 0.366301
PTGDR2 prostaglandin D2 receptor 2 0.363347
TAC1 tachykinin, precursor 1 0.362239
GJB6 gap junction protein, beta 6, 30kDa 0.360395
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.357814
CNOT1 CCR4-NOT transcription complex, subunit 1 0.354499
IL33 interleukin 33 0.351923
PTAFR platelet-activating factor receptor 0.351555
ENSA endosulfine alpha 0.350452
PLGLB1 plasminogen-like B1 0.349717
CERK ceramide kinase 0.345308
ZFP36 ZFP36 ring finger protein 0.343106
SAA1 serum amyloid A1 0.339073
PRTN3 proteinase 3 0.336876
YBX2 Y box binding protein 2 0.324094
SUCLG1 succinate-CoA ligase, alpha subunit 0.324094
MPO myeloperoxidase 0.314278
CCR2 chemokine (C-C motif) receptor 2 0.304864
HIST1H1A histone cluster 1, H1a 0.304142
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) 0.300533
TMPRSS13 transmembrane protease, serine 13 0.292616
PRKCG protein kinase C, gamma 0.285086
GGCT gamma-glutamylcyclotransferase 0.284371
PLA2G10 phospholipase A2, group X 0.284371
GJB4 gap junction protein, beta 4, 30.3kDa 0.28294
SART1 squamous cell carcinoma antigen recognized by T cells 0.279367
PRSS21 protease, serine, 21 (testisin) 0.272953
CXCL10 chemokine (C-X-C motif) ligand 10 0.266203
TIMELESS timeless circadian clock 0.26514
AFF1 AF4/FMR2 family, member 1 0.264785
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.262306
SOCS3 suppressor of cytokine signaling 3 0.262306
IL5 interleukin 5 0.260184
PKD2L1 polycystic kidney disease 2-like 1 0.257005
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.255594
CISH cytokine inducible SH2-containing protein 0.253479
PTGDR prostaglandin D2 receptor (DP) 0.251015
TGM1 transglutaminase 1 0.250311
AFF2 AF4/FMR2 family, member 2 0.24996
CTBP1 C-terminal binding protein 1 0.248905
LCN1 lipocalin 1 0.248203
IFNB1 interferon, beta 1, fibroblast 0.247501
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.242945
RENBP renin binding protein 0.241895
GPR148 G protein-coupled receptor 148 0.238403
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.237357
CCL13 chemokine (C-C motif) ligand 13 0.237009
CCNE1 cyclin E1 0.226952
CD68 CD68 molecule 0.225573
DSG3 desmoglein 3 0.222822
CASP14 caspase 14, apoptosis-related cysteine peptidase 0.22145
CASP5 caspase 5, apoptosis-related cysteine peptidase 0.220766
BTLA B and T lymphocyte associated 0.220424
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.220424
EDA ectodysplasin A 0.21974
IL1A interleukin 1, alpha 0.218715
SH2D3A SH2 domain containing 3A 0.216672
AADACL3 arylacetamide deacetylase-like 3 0.216332
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.215653
NBPF8 neuroblastoma breakpoint family, member 8 0.215314
TLR5 toll-like receptor 5 0.212271
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) 0.200982
BCAM basal cell adhesion molecule (Lutheran blood group) 0.198709
CD22 CD22 molecule 0.196459
CKAP5 cytoskeleton associated protein 5 0.19582
MUC4 mucin 4, cell surface associated 0.195501
HLA-B major histocompatibility complex, class I, B 0.195501
ADA adenosine deaminase 0.194232
CXCL9 chemokine (C-X-C motif) ligand 9 0.1936
DOCK8 dedicator of cytokinesis 8 0.191408
CCL5 chemokine (C-C motif) ligand 5 0.188938
WDFY2 WD repeat and FYVE domain containing 2 0.187415
PTPRJ protein tyrosine phosphatase, receptor type, J 0.18651
ADAM10 ADAM metallopeptidase domain 10 0.18621
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.185313
POLK polymerase (DNA directed) kappa 0.183541
RAG1 recombination activating gene 1 0.180652
SRRM1 serine/arginine repetitive matrix 1 0.180367
FPR1 formyl peptide receptor 1 0.177851
SCP2 sterol carrier protein 2 0.174093
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.174093
KCNK2 potassium channel, two pore domain subfamily K, member 2 0.173832
HTRA3 HtrA serine peptidase 3 0.172799
TLR2 toll-like receptor 2 0.172291
TF transferrin 0.170789
CXCL8 chemokine (C-X-C motif) ligand 8 0.170789
PLCH2 phospholipase C, eta 2 0.170299
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 0.16933
SDCBP syndecan binding protein (syntenin) 0.167452
CCL25 chemokine (C-C motif) ligand 25 0.167452
IL10 interleukin 10 0.167224
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.165217
MYD88 myeloid differentiation primary response 88 0.164149
TADA1 transcriptional adaptor 1 0.163523
FOXP3 forkhead box P3 0.163317
ANXA1 annexin A1 0.163111
BCOR BCL6 corepressor 0.160203
KRT3 keratin 3, type II 0.159124
RSPO1 R-spondin 1 0.158951
IL2RA interleukin 2 receptor, alpha 0.158605
CCL15 chemokine (C-C motif) ligand 15 0.143246
OR6B2 olfactory receptor, family 6, subfamily B, member 2 0.141757
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) 0.141591
ACVR1 activin A receptor, type I 0.140954
CLTC clathrin, heavy chain (Hc) 0.140732
TIMP2 TIMP metallopeptidase inhibitor 2 0.140515
OR10T2 olfactory receptor, family 10, subfamily T, member 2 0.139152
FH fumarate hydratase 0.138742
TYR tyrosinase 0.138691
ACVRL1 activin A receptor type II-like 1 0.138332
IL6R interleukin 6 receptor 0.13772
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) 0.136577
GPI glucose-6-phosphate isomerase 0.136496
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.135977
NELFCD negative elongation factor complex member C/D 0.135876
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.135863
APOLD1 apolipoprotein L domain containing 1 0.1342
PTER phosphotriesterase related 0.133692
TNC tenascin C 0.133171
HBB hemoglobin, beta 0.132523
STYK1 serine/threonine/tyrosine kinase 1 0.132217
C5AR1 complement component 5a receptor 1 0.130664
CD1D CD1d molecule 0.127452
IL33R interleukin 33 receptor 0.126844
RNGTT RNA guanylyltransferase and 5'-phosphatase 0.124329
PRDM16 PR domain containing 16 0.124125
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.124088
NGF nerve growth factor (beta polypeptide) 0.123797
CCL17 chemokine (C-C motif) ligand 17 0.123223
GADD45B growth arrest and DNA-damage-inducible, beta 0.123018
KRT15 keratin 15, type I 0.122863
DLL4 delta-like 4 (Drosophila) 0.122471
SERPINB1 serpin peptidase inhibitor, clade B (ovalbumin), member 1 0.122391
MCF2 MCF.2 cell line derived transforming sequence 0.122042
PTGER4 prostaglandin E receptor 4 (subtype EP4) 0.121547
SACS sacsin molecular chaperone 0.121491
FLG filaggrin 0.121153
CCR4 chemokine (C-C motif) receptor 4 0.120753
CCR7 chemokine (C-C motif) receptor 7 0.119954
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 0.119908
ICAM2 intercellular adhesion molecule 2 0.119281
CYSLTR2 cysteinyl leukotriene receptor 2 0.118649
JAG2 jagged 2 0.118194
MIXL1 Mix paired-like homeobox 0.118161
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 0.116711
WARS tryptophanyl-tRNA synthetase 0.116467
TLR4 toll-like receptor 4 0.116398
CD70 CD70 molecule 0.115755
TBXA2R thromboxane A2 receptor 0.115393
CRB1 crumbs family member 1, photoreceptor morphogenesis associated 0.115171
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.113439
HLA-DMA major histocompatibility complex, class II, DM alpha 0.112908
BAG1 BCL2-associated athanogene 0.112908
GAN gigaxonin 0.112665
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.112503
CHD7 chromodomain helicase DNA binding protein 7 0.110478
EDNRB endothelin receptor type B 0.10903
NBPF10 neuroblastoma breakpoint family, member 10 0.108825
CCL19 chemokine (C-C motif) ligand 19 0.108121
CALR calreticulin 0.105996
PSEN2 presenilin 2 0.104362
PNMA2 paraneoplastic Ma antigen 2 0.101776
FYN FYN proto-oncogene, Src family tyrosine kinase 0.095661
GGT2 gamma-glutamyltransferase 2 0.095602
CTSG cathepsin G 0.094501
POMC proopiomelanocortin 0.090497
COL7A1 collagen, type VII, alpha 1 0.089447
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.088126
MMP9 matrix metallopeptidase 9 0.087639
MUC1 mucin 1, cell surface associated 0.08672
CSF3 colony stimulating factor 3 (granulocyte) 0.086128
FN1 fibronectin 1 0.085662
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.084797
PTPRC protein tyrosine phosphatase, receptor type, C 0.083347
MMP8 matrix metallopeptidase 8 0.08287
B2M beta-2-microglobulin 0.081948
ATM ATM serine/threonine kinase 0.081122
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 0.079527
ACPP acid phosphatase, prostate 0.078268
ICAM3 intercellular adhesion molecule 3 0.077774
GGT1 gamma-glutamyltransferase 1 0.076929
LCK LCK proto-oncogene, Src family tyrosine kinase 0.075543
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.074792