conjunctivitis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description Conjunctivitis is a conjunctival disease described as a inflammation of the conjunctiva, the outermost layer of the eye and the inner surface of the eyelids, which is most commonly due to an allergic reaction or an infection (usually viral, but sometimes bacterial. Fungal infections are rare and occur mainly in people who use corticosteroid eye drops for a long time or have eye injuries involving vegetable matter. Newborns are particularly susceptible to eye infections, which they acquire from organisms in the mother's birth canal (neonatal conjunctivitis. (Human Disease Ontology, DOID_6195)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0001852
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Genes

21 gene mutations causing the conjunctivitis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
CEBPE CCAAT/enhancer binding protein (C/EBP), epsilon
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
DSG3 desmoglein 3
DST dystonin
EDA ectodysplasin A
FAS Fas cell surface death receptor
FES FES proto-oncogene, tyrosine kinase
FIGN fidgetin
FOXP3 forkhead box P3
IL6ST interleukin 6 signal transducer
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
PLG plasminogen
RAD23B RAD23 homolog B (S. cerevisiae)
SFTPC surfactant protein C
SNAI2 snail family zinc finger 2
SYNE1 spectrin repeat containing, nuclear envelope 1
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TOM1L2 target of myb1-like 2 (chicken)
TP73 tumor protein p73
ZFP36 ZFP36 ring finger protein