conn's syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description An adrenal admenoma characterized by over production of aldosterone. (Human Disease Ontology, DOID_12028)
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Genes

92 genes co-occuring with the disease conn's syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
REN renin 3.26505
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 2.39641
NR3C2 nuclear receptor subfamily 3, group C, member 2 2.21217
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5 2.17706
POMC proopiomelanocortin 2.04236
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1 1.67819
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 1.60949
ATP1A4 ATPase, Na+/K+ transporting, alpha 4 polypeptide 1.52864
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 1.461
NPPA natriuretic peptide A 1.37556
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.30794
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide 1.23516
KCNK9 potassium channel, two pore domain subfamily K, member 9 1.1841
ACE angiotensin I converting enzyme 1.02988
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2 0.892948
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.871643
ZFP37 ZFP37 zinc finger protein 0.859771
ASPH aspartate beta-hydroxylase 0.859362
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 0.808539
C5ORF38 chromosome 5 open reading frame 38 0.804436
PRSS8 protease, serine, 8 0.795002
NDUFA8 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa 0.794181
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 0.743954
KCNK3 potassium channel, two pore domain subfamily K, member 3 0.741517
PSMG4 proteasome (prosome, macropain) assembly chaperone 4 0.740299
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.711183
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.668345
MEN1 multiple endocrine neoplasia I 0.640645
CYTL1 cytokine-like 1 0.623751
NAGS N-acetylglutamate synthase 0.619051
NR5A1 nuclear receptor subfamily 5, group A, member 1 0.612011
ARHGAP9 Rho GTPase activating protein 9 0.592895
DNAH8 dynein, axonemal, heavy chain 8 0.590558
CAMK1 calcium/calmodulin-dependent protein kinase I 0.581217
NR4A2 nuclear receptor subfamily 4, group A, member 2 0.58005
AMY2A amylase, alpha 2A (pancreatic) 0.555956
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.529994
INS insulin 0.521888
AGTR1 angiotensin II receptor, type 1 0.521117
ADM adrenomedullin 0.513802
PTH parathyroid hormone 0.505739
HLA-DMA major histocompatibility complex, class II, DM alpha 0.497703
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 0.490454
KCNK5 potassium channel, two pore domain subfamily K, member 5 0.481325
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.472982
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta 0.470711
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.470711
KCNK1 potassium channel, two pore domain subfamily K, member 1 0.462772
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.452962
FDX1 ferredoxin 1 0.449947
KNG1 kininogen 1 0.413901
KIN Kin17 DNA and RNA binding protein 0.405678
PBK PDZ binding kinase 0.401945
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1 0.395235
ALB albumin 0.362239
KLHL3 kelch-like family member 3 0.354868
CAMK1D calcium/calmodulin-dependent protein kinase ID 0.353763
TDGF1 teratocarcinoma-derived growth factor 1 0.32993
CLCNKB chloride channel, voltage-sensitive Kb 0.321909
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.318635
TRHR thyrotropin-releasing hormone receptor 0.299812
AVP arginine vasopressin 0.299452
UNK unkempt family zinc finger 0.298731
PDE9A phosphodiesterase 9A 0.295492
ARR3 arrestin 3, retinal (X-arrestin) 0.279367
STAR steroidogenic acute regulatory protein 0.279011
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.279011
EDN1 endothelin 1 0.264785
TENM1 teneurin transmembrane protein 1 0.255594
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 0.253479
GNRHR gonadotropin-releasing hormone receptor 0.252774
INSR insulin receptor 0.241196
CRH corticotropin releasing hormone 0.233183
UTS2 urotensin 2 0.230409
LRP1B low density lipoprotein receptor-related protein 1B 0.229716
CA1 carbonic anhydrase I 0.212608
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit 0.20658
HAND2 heart and neural crest derivatives expressed 2 0.204263
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.203604
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.202946
KDM5C lysine (K)-specific demethylase 5C 0.201308
SAMD11 sterile alpha motif domain containing 11 0.198709
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.198064
MGAM maltase-glucoamylase 0.196779
KCNJ3 potassium channel, inwardly rectifying subfamily J, member 3 0.188022
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.180652
AGTR2 angiotensin II receptor, type 2 0.17896
UTS2R urotensin 2 receptor 0.171286
RNASEH2A ribonuclease H2, subunit A 0.165217
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.163523
ALDOB aldolase B, fructose-bisphosphate 0.162306
CYBA cytochrome b-245, alpha polypeptide 0.159302