content Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

439 genes co-occuring with the biological term content in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAT1 acetyl-CoA acetyltransferase 1
ACHE acetylcholinesterase (Yt blood group)
ACTN2 actinin, alpha 2
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADAR adenosine deaminase, RNA-specific
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRA2A adrenoceptor alpha 2A
ADRA2B adrenoceptor alpha 2B
ADRBK1 adrenergic, beta, receptor kinase 1
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALOX15 arachidonate 15-lipoxygenase
ALOX5 arachidonate 5-lipoxygenase
ANXA1 annexin A1
AOC3 amine oxidase, copper containing 3
APOA1 apolipoprotein A-I
APOA5 apolipoprotein A-V
APOB apolipoprotein B
APOC3 apolipoprotein C-III
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AR androgen receptor
ARF4 ADP-ribosylation factor 4
ARF5 ADP-ribosylation factor 5
ARL2 ADP-ribosylation factor-like 2
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5
ARSA arylsulfatase A
ARSB arylsulfatase B
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
ATF3 activating transcription factor 3
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3
ATP4B ATPase, H+/K+ exchanging, beta polypeptide
ATPIF1 ATPase inhibitory factor 1
AZF1 azoospermia factor 1
B2M beta-2-microglobulin
BAX BCL2-associated X protein
BBS12 Bardet-Biedl syndrome 12
BCHE butyrylcholinesterase
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BIRC5 baculoviral IAP repeat containing 5
BMP2 bone morphogenetic protein 2
C10ORF2 chromosome 10 open reading frame 2
CALB2 calbindin 2
CALCA calcitonin-related polypeptide alpha
CAPN2 calpain 2, (m/II) large subunit
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CASQ2 calsequestrin 2 (cardiac muscle)
CAST calpastatin
CAT catalase
CBR4 carbonyl reductase 4
CBS cystathionine-beta-synthase
CCL2 chemokine (C-C motif) ligand 2
CCNB1 cyclin B1
CD34 CD34 molecule
CD36 CD36 molecule (thrombospondin receptor)
CD70 CD70 molecule
CDK1 cyclin-dependent kinase 1
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CES1 carboxylesterase 1
CETP cholesteryl ester transfer protein, plasma
CFL1 cofilin 1 (non-muscle)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHUK conserved helix-loop-helix ubiquitous kinase
CIB1 calcium and integrin binding 1 (calmyrin)
CKB creatine kinase, brain
CLEC5A C-type lectin domain family 5, member A
CLN3 ceroid-lipofuscinosis, neuronal 3
CLU clusterin
CNDP1 carnosine dipeptidase 1 (metallopeptidase M20 family)
CNR2 cannabinoid receptor 2 (macrophage)
CNSN Carnosinemia (carnosinase)
COL1A1 collagen, type I, alpha 1
COL3A1 collagen, type III, alpha 1
COMT catechol-O-methyltransferase
COQ4 coenzyme Q4
CPT1A carnitine palmitoyltransferase 1A (liver)
CREM cAMP responsive element modulator
CRLS1 cardiolipin synthase 1
CRTAP cartilage associated protein
CSF1R colony stimulating factor 1 receptor
CST3 cystatin C
CTCF CCCTC-binding factor (zinc finger protein)
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTGF connective tissue growth factor
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSB cathepsin B
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CYBA cytochrome b-245, alpha polypeptide
CYBB cytochrome b-245, beta polypeptide
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP3A cytochrome P450, family 3, subfamily A
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DAO D-amino-acid oxidase
DCN decorin
DGAT2 diacylglycerol O-acyltransferase 2
DHCR24 24-dehydrocholesterol reductase
DIABLO diablo, IAP-binding mitochondrial protein
DKK3 dickkopf WNT signaling pathway inhibitor 3
DMBT1 deleted in malignant brain tumors 1
DMD dystrophin
DMRT1 doublesex and mab-3 related transcription factor 1
DSP desmoplakin
DUSP3 dual specificity phosphatase 3
EGFR epidermal growth factor receptor
ELANE elastase, neutrophil expressed
ELAVL1 ELAV like RNA binding protein 1
ELN elastin
EMD emerin
ENHO energy homeostasis associated
ENO2 enolase 2 (gamma, neuronal)
EPO erythropoietin
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F10 coagulation factor X
F2R coagulation factor II (thrombin) receptor
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FABP2 fatty acid binding protein 2, intestinal
FABP4 fatty acid binding protein 4, adipocyte
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FGB fibrinogen beta chain
FGF21 fibroblast growth factor 21
FGF7 fibroblast growth factor 7
FGG fibrinogen gamma chain
FN1 fibronectin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FPR1 formyl peptide receptor 1
FRA1H fragile site, 5-azacytidine type, common, fra(1)(q42)
FSHR follicle stimulating hormone receptor
FTO fat mass and obesity associated
FYN FYN proto-oncogene, Src family tyrosine kinase
G0S2 G0/G1 switch 2
GAA glucosidase, alpha; acid
GADD45A growth arrest and DNA-damage-inducible, alpha
GAL galanin/GMAP prepropeptide
GALNS galactosamine (N-acetyl)-6-sulfatase
GARS glycyl-tRNA synthetase
GATA1 GATA binding protein 1 (globin transcription factor 1)
GCG glucagon
GCLC glutamate-cysteine ligase, catalytic subunit
GDF5 growth differentiation factor 5
GHRL ghrelin/obestatin prepropeptide
GIP gastric inhibitory polypeptide
GLCE glucuronic acid epimerase
GLTP glycolipid transfer protein
GOLM1 golgi membrane protein 1
GP1BB glycoprotein Ib (platelet), beta polypeptide
GPC1 glypican 1
GPR119 G protein-coupled receptor 119
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GPX1 glutathione peroxidase 1
GPX4 glutathione peroxidase 4
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIA2 glutamate receptor, ionotropic, AMPA 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GSR glutathione reductase
GSTA1 glutathione S-transferase alpha 1
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
GYG1 glycogenin 1
HAS1 hyaluronan synthase 1
HAS2 hyaluronan synthase 2
HAS3 hyaluronan synthase 3
HBA1 hemoglobin, alpha 1
HDC histidine decarboxylase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-B major histocompatibility complex, class I, B
HLA-G major histocompatibility complex, class I, G
HMOX2 heme oxygenase 2
HNF4A hepatocyte nuclear factor 4, alpha
HP haptoglobin
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HYAL2 hyaluronoglucosaminidase 2
IFITM3 interferon induced transmembrane protein 3
IFT57 intraflagellar transport 57
IGBP1 immunoglobulin (CD79A) binding protein 1
IGFALS insulin-like growth factor binding protein, acid labile subunit
IHH indian hedgehog
IL10 interleukin 10
IL18 interleukin 18
IL1B interleukin 1, beta
IL2 interleukin 2
IL20 interleukin 20
IL20RA interleukin 20 receptor, alpha
IL20RB interleukin 20 receptor beta
ILDR1 immunoglobulin-like domain containing receptor 1
ILF3 interleukin enhancer binding factor 3, 90kDa
INHBA inhibin, beta A
INS insulin
INSRR insulin receptor-related receptor
ITM2B integral membrane protein 2B
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT18 keratin 18, type I
LAMB1 laminin, beta 1
LDHA lactate dehydrogenase A
LEP leptin
LEPR leptin receptor
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LHB luteinizing hormone beta polypeptide
LIPA lipase A, lysosomal acid, cholesterol esterase
LIPE lipase, hormone-sensitive
LIPG lipase, endothelial
LMNA lamin A/C
LOXL1 lysyl oxidase-like 1
LPL lipoprotein lipase
LTF lactotransferrin
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
LYZ lysozyme
MAGEC1 melanoma antigen family C1
MAGEC2 melanoma antigen family C2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MARVELD2 MARVEL domain containing 2
MAT2B methionine adenosyltransferase II, beta
MBD2 methyl-CpG binding domain protein 2
MED1 mediator complex subunit 1
MEDAG mesenteric estrogen-dependent adipogenesis
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MGMT O-6-methylguanine-DNA methyltransferase
MIR145 microRNA 145
MIR27B microRNA 27b
MKI67 marker of proliferation Ki-67
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP20 matrix metallopeptidase 20
MMP7 matrix metallopeptidase 7
MMP8 matrix metallopeptidase 8
MMP9 matrix metallopeptidase 9
MSTN myostatin
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTTP microsomal triglyceride transfer protein
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYH2 myosin, heavy chain 2, skeletal muscle, adult
NAMPT nicotinamide phosphoribosyltransferase
NCOA1 nuclear receptor coactivator 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NES nestin
NEU1 sialidase 1 (lysosomal sialidase)
NEU3 sialidase 3 (membrane sialidase)
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NGF nerve growth factor (beta polypeptide)
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX4 NADPH oxidase 4
NPC1 Niemann-Pick disease, type C1
NPTX2 neuronal pentraxin II
NRIP1 nuclear receptor interacting protein 1
OCA2 oculocutaneous albinism II
OGG1 8-oxoguanine DNA glycosylase
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OXT oxytocin/neurophysin I prepropeptide
OXTR oxytocin receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P3H2 prolyl 3-hydroxylase 2
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PCNA proliferating cell nuclear antigen
PCSK2 proprotein convertase subtilisin/kexin type 2
PCYOX1 prenylcysteine oxidase 1
PDCD6IP programmed cell death 6 interacting protein
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PF4 platelet factor 4
PGR progesterone receptor
PKP1 plakophilin 1
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLIN1 perilipin 1
PLIN2 perilipin 2
PLIN3 perilipin 3
PLIN4 perilipin 4
PLTP phospholipid transfer protein
PML promyelocytic leukemia
PNPLA2 patatin-like phospholipase domain containing 2
PNPLA3 patatin-like phospholipase domain containing 3
POLG polymerase (DNA directed), gamma
POLG2 polymerase (DNA directed), gamma 2, accessory subunit
PON1 paraoxonase 1
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
PRKAG3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRKG1 protein kinase, cGMP-dependent, type I
PRL prolactin
PRSS3 protease, serine, 3
PSEN1 presenilin 1
PSEN2 presenilin 2
PTBP1 polypyrimidine tract binding protein 1
PTBP2 polypyrimidine tract binding protein 2
PTEN phosphatase and tensin homolog
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTTG1 pituitary tumor-transforming 1
PVALB parvalbumin
PYY peptide YY
RAB3A RAB3A, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RARA retinoic acid receptor, alpha
RBP4 retinol binding protein 4, plasma
RCVRN recoverin
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RETN resistin
RORC RAR-related orphan receptor C
RPS29 ribosomal protein S29
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
S100A7A S100 calcium binding protein A7A
S100A9 S100 calcium binding protein A9
SCARB1 scavenger receptor class B, member 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SCN5A sodium channel, voltage gated, type V alpha subunit
SCO1 SCO1 cytochrome c oxidase assembly protein
SCO2 SCO2 cytochrome c oxidase assembly protein
SDC1 syndecan 1
SEPP1 selenoprotein P, plasma, 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGMS1 sphingomyelin synthase 1
SIRT1 sirtuin 1
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC16A4 solute carrier family 16, member 4
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC25A19 solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC30A4 solute carrier family 30 (zinc transporter), member 4
SLC31A1 solute carrier family 31 (copper transporter), member 1
SLC34A2 solute carrier family 34 (type II sodium/phosphate cotransporter), member 2
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMAD3 SMAD family member 3
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOD1 superoxide dismutase 1, soluble
SOD2 superoxide dismutase 2, mitochondrial
SOST sclerostin
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SPPL2B signal peptide peptidase like 2B
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
SRPK1 SRSF protein kinase 1
SRSF1 serine/arginine-rich splicing factor 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SURF1 surfeit 1
TAS1R2 taste receptor, type 1, member 2
TF transferrin
TFEB transcription factor EB
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFRC transferrin receptor
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TH tyrosine hydroxylase
THBS1 thrombospondin 1
TIMP1 TIMP metallopeptidase inhibitor 1
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TM6SF2 transmembrane 6 superfamily member 2
TMPRSS6 transmembrane protease, serine 6
TNF tumor necrosis factor
TNXB tenascin XB
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TRIM63 tripartite motif containing 63, E3 ubiquitin protein ligase
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPO translocator protein (18kDa)
TUBA1A tubulin, alpha 1a
TXN thioredoxin
TXNDC8 thioredoxin domain containing 8 (spermatozoa)
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UCP3 uncoupling protein 3 (mitochondrial, proton carrier)
UGDH UDP-glucose 6-dehydrogenase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
USP2 ubiquitin specific peptidase 2
VCAN versican
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VIM vimentin
VWF von Willebrand factor
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPC xeroderma pigmentosum, complementation group C
YY1 YY1 transcription factor
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFPM1 zinc finger protein, FOG family member 1