controlling Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The act of directing or determining; regulation or maintenance of a function or action; a relation of constraint of one entity (thing or person or group) by another.|A control role is borne by a material in a process in which results obtained from an experimental sample and a control sample are compared. (Experimental Factor Ontology, EFO_0001461)
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Genes

922 genes co-occuring with the biological term controlling in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A1CF APOBEC1 complementation factor
A2M alpha-2-macroglobulin
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
ACHE acetylcholinesterase (Yt blood group)
ADA adenosine deaminase
ADAM10 ADAM metallopeptidase domain 10
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADORA1 adenosine A1 receptor
ADORA3 adenosine A3 receptor
ADRB2 adrenoceptor beta 2, surface
ADRM1 adhesion regulating molecule 1
AFAP1L2 actin filament associated protein 1-like 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
AKAP12 A kinase (PRKA) anchor protein 12
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
AMELX amelogenin, X-linked
AMH anti-Mullerian hormone
AMICA1 adhesion molecule, interacts with CXADR antigen 1
AMOT angiomotin
ANGPT1 angiopoietin 1
ANXA1 annexin A1
ANXA2 annexin A2
AOC3 amine oxidase, copper containing 3
APC adenomatous polyposis coli
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP7 aquaporin 7
AQP9 aquaporin 9
AR androgen receptor
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARF1 ADP-ribosylation factor 1
ARF6 ADP-ribosylation factor 6
ARHGAP31 Rho GTPase activating protein 31
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ATG12 autophagy related 12
ATG14 autophagy related 14
ATG5 autophagy related 5
ATM ATM serine/threonine kinase
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATR ATR serine/threonine kinase
ATRN attractin
AURKA aurora kinase A
AURKB aurora kinase B
AXIN1 axin 1
AXIN2 axin 2
AXL AXL receptor tyrosine kinase
B2M beta-2-microglobulin
B3GAT3 beta-1,3-glucuronyltransferase 3
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAG3 BCL2-associated athanogene 3
BAX BCL2-associated X protein
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2A1 BCL2-related protein A1
BCL2L1 BCL2-like 1
BCL2L14 BCL2-like 14 (apoptosis facilitator)
BCL6 B-cell CLL/lymphoma 6
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BGN biglycan
BID BH3 interacting domain death agonist
BIRC7 baculoviral IAP repeat containing 7
BMP1 bone morphogenetic protein 1
BMP2 bone morphogenetic protein 2
BMP7 bone morphogenetic protein 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BSG basigin (Ok blood group)
BST2 bone marrow stromal cell antigen 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C3 complement component 3
CADM1 cell adhesion molecule 1
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CAMP cathelicidin antimicrobial peptide
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC8 coiled-coil domain containing 8
CCL20 chemokine (C-C motif) ligand 20
CCL3 chemokine (C-C motif) ligand 3
CCNA1 cyclin A1
CCNB1 cyclin B1
CCND1 cyclin D1
CCNT1 cyclin T1
CCP110 centriolar coiled coil protein 110kDa
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR9 chemokine (C-C motif) receptor 9
CD163 CD163 molecule
CD209 CD209 molecule
CD244 CD244 molecule, natural killer cell receptor 2B4
CD274 CD274 molecule
CD276 CD276 molecule
CD34 CD34 molecule
CD4 CD4 molecule
CD46 CD46 molecule, complement regulatory protein
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CD82 CD82 molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK1 cyclin-dependent kinase 1
CDK11B cyclin-dependent kinase 11B
CDK2 cyclin-dependent kinase 2
CDK6 cyclin-dependent kinase 6
CDKL5 cyclin-dependent kinase-like 5
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDX2 caudal type homeobox 2
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPJ centromere protein J
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGB chorionic gonadotropin, beta polypeptide
CHEK1 checkpoint kinase 1
CHIT1 chitinase 1 (chitotriosidase)
CHRM2 cholinergic receptor, muscarinic 2
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CHUK conserved helix-loop-helix ubiquitous kinase
CKAP4 cytoskeleton-associated protein 4
CLASP2 cytoplasmic linker associated protein 2
CLCN1 chloride channel, voltage-sensitive 1
CLDN5 claudin 5
CLEC16A C-type lectin domain family 16, member A
CLN5 ceroid-lipofuscinosis, neuronal 5
CLSPN claspin
CNR2 cannabinoid receptor 2 (macrophage)
CNTROB centrobin, centrosomal BRCA2 interacting protein
COG1 component of oligomeric golgi complex 1
COG5 component of oligomeric golgi complex 5
COG7 component of oligomeric golgi complex 7
COIL coilin
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CROT carnitine O-octanoyltransferase
CRY1 cryptochrome circadian clock 1
CSNK1D casein kinase 1, delta
CST6 cystatin E/M
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTBP1 C-terminal binding protein 1
CTCF CCCTC-binding factor (zinc finger protein)
CTCFL CCCTC-binding factor (zinc finger protein)-like
CTDSP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTSB cathepsin B
CUL3 cullin 3
CUL7 cullin 7
CUL9 cullin 9
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR5 chemokine (C-X-C motif) receptor 5
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAPK1 death-associated protein kinase 1
DAXX death-domain associated protein
DCP1A decapping mRNA 1A
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEPTOR DEP domain containing MTOR-interacting protein
DGKZ diacylglycerol kinase, zeta
DICER1 dicer 1, ribonuclease type III
DIO3 deiodinase, iodothyronine, type III
DIRAS3 DIRAS family, GTP-binding RAS-like 3
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DLK1 delta-like 1 homolog (Drosophila)
DLL4 delta-like 4 (Drosophila)
DMPK dystrophia myotonica-protein kinase
DNAH11 dynein, axonemal, heavy chain 11
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOCK2 dedicator of cytokinesis 2
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DRD5 dopamine receptor D5
DSC2 desmocollin 2
DSG2 desmoglein 2
DST dystonin
DUSP6 dual specificity phosphatase 6
DYNLT1 dynein, light chain, Tctex-type 1
DYX1C1 dyslexia susceptibility 1 candidate 1
DYX8 dyslexia susceptibility 8
E2F1 E2F transcription factor 1
E2F8 E2F transcription factor 8
EBAG9 estrogen receptor binding site associated, antigen, 9
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EED embryonic ectoderm development
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EHD2 EH-domain containing 2
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF4E eukaryotic translation initiation factor 4E
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELK1 ELK1, member of ETS oncogene family
ELMO1 engulfment and cell motility 1
EME1 essential meiotic structure-specific endonuclease 1
EMILIN1 elastin microfibril interfacer 1
EN1 engrailed homeobox 1
ENO1 enolase 1, (alpha)
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ENTPD3 ectonucleoside triphosphate diphosphohydrolase 3
EPB41 erythrocyte membrane protein band 4.1
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EWSR1 EWS RNA-binding protein 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
EZR ezrin
F11R F11 receptor
F2 coagulation factor II (thrombin)
F8 coagulation factor VIII, procoagulant component
FADD Fas (TNFRSF6)-associated via death domain
FAM102A family with sequence similarity 102, member A
FAM129B family with sequence similarity 129, member B
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
FBLN5 fibulin 5
FBXL17 F-box and leucine-rich repeat protein 17
FBXL4 F-box and leucine-rich repeat protein 4
FBXL7 F-box and leucine-rich repeat protein 7
FBXO11 F-box protein 11
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCAR Fc fragment of IgA receptor
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FERMT1 fermitin family member 1
FERMT3 fermitin family member 3
FGA fibrinogen alpha chain
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF13 fibroblast growth factor 13
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FIBCD1 fibrinogen C domain containing 1
FLNA filamin A, alpha
FLT1 fms-related tyrosine kinase 1
FLVCR1 feline leukemia virus subgroup C cellular receptor 1
FMOD fibromodulin
FMR1 fragile X mental retardation 1
FN1 fibronectin 1
FOXA1 forkhead box A1
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FOXP3 forkhead box P3
FOXQ1 forkhead box Q1
FPR2 formyl peptide receptor 2
FSTL1 follistatin-like 1
FTMT ferritin mitochondrial
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FXN frataxin
FXYD1 FXYD domain containing ion transport regulator 1
G6PD glucose-6-phosphate dehydrogenase
GADD45G growth arrest and DNA-damage-inducible, gamma
GALC galactosylceramidase
GBA glucosidase, beta, acid
GCM1 glial cells missing homolog 1 (Drosophila)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GDI1 GDP dissociation inhibitor 1
GFI1B growth factor independent 1B transcription repressor
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GH1 growth hormone 1
GHRL ghrelin/obestatin prepropeptide
GJA1 gap junction protein, alpha 1, 43kDa
GJB2 gap junction protein, beta 2, 26kDa
GLI1 GLI family zinc finger 1
GLI3 GLI family zinc finger 3
GLTSCR2 glioma tumor suppressor candidate region gene 2
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GOLGA2 golgin A2
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GORASP1 golgi reassembly stacking protein 1, 65kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GP1BB glycoprotein Ib (platelet), beta polypeptide
GRB14 growth factor receptor-bound protein 14
GRHL2 grainyhead-like 2 (Drosophila)
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3B glycogen synthase kinase 3 beta
GTF2I general transcription factor IIi
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
GZMM granzyme M (lymphocyte met-ase 1)
H2AFX H2A histone family, member X
HAMP hepcidin antimicrobial peptide
HARS histidyl-tRNA synthetase
HBA1 hemoglobin, alpha 1
HBB hemoglobin, beta
HCFC1 host cell factor C1
HCK HCK proto-oncogene, Src family tyrosine kinase
HCST hematopoietic cell signal transducer
HDAC2 histone deacetylase 2
HDAC5 histone deacetylase 5
HDAC6 histone deacetylase 6
HFE hemochromatosis
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-G major histocompatibility complex, class I, G
HLTF helicase-like transcription factor
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMOX2 heme oxygenase 2
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOPX HOP homeobox
HP haptoglobin
HPSE heparanase
HRH3 histamine receptor H3
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2
HSF1 heat shock transcription factor 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB1 heat shock 27kDa protein 1
HSPB8 heat shock 22kDa protein 8
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTRA1 HtrA serine peptidase 1
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
ICOS inducible T-cell co-stimulator
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IER3 immediate early response 3
IFNA1 interferon, alpha 1
IFNG interferon, gamma
IFT88 intraflagellar transport 88
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2R insulin-like growth factor 2 receptor
IGFBP3 insulin-like growth factor binding protein 3
IGFBP5 insulin-like growth factor binding protein 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL10 interleukin 10
IL13 interleukin 13
IL15 interleukin 15
IL17A interleukin 17A
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1R2 interleukin 1 receptor, type II
IL2 interleukin 2
IL22 interleukin 22
IL32 interleukin 32
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
ILK integrin-linked kinase
INHA inhibin, alpha
IRF1 interferon regulatory factor 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF2BPL interferon regulatory factor 2 binding protein-like
IRF3 interferon regulatory factor 3
ITGA1 integrin, alpha 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
ITGAD integrin, alpha D
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITSN2 intersectin 2
IVL involucrin
JAG1 jagged 1
JAG2 jagged 2
JAK2 Janus kinase 2
JMJD6 jumonji domain containing 6
JUN jun proto-oncogene
JUNB jun B proto-oncogene
JUP junction plakoglobin
KAT2A K(lysine) acetyltransferase 2A
KAT2B K(lysine) acetyltransferase 2B
KAT5 K(lysine) acetyltransferase 5
KCNA2 potassium channel, voltage gated shaker related subfamily A, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM4A lysine (K)-specific demethylase 4A
KDM6A lysine (K)-specific demethylase 6A
KDR kinase insert domain receptor
KEAP1 kelch-like ECH-associated protein 1
KIF18A kinesin family member 18A
KIF1A kinesin family member 1A
KIF2C kinesin family member 2C
KIFC1 kinesin family member C1
KISS1 KiSS-1 metastasis-suppressor
KITLG KIT ligand
KLF2 Kruppel-like factor 2
KLF4 Kruppel-like factor 4 (gut)
KLF5 Kruppel-like factor 5 (intestinal)
KLF9 Kruppel-like factor 9
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LATS1 large tumor suppressor kinase 1
LCN2 lipocalin 2
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LCRB locus control region, beta
LEP leptin
LETM1 leucine zipper-EF-hand containing transmembrane protein 1
LGALS1 lectin, galactoside-binding, soluble, 1
LGALS3 lectin, galactoside-binding, soluble, 3
LGMN legumain
LHCGR luteinizing hormone/choriogonadotropin receptor
LHX9 LIM homeobox 9
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
LMAN1 lectin, mannose-binding, 1
LMNA lamin A/C
LPL lipoprotein lipase
LRP1 low density lipoprotein receptor-related protein 1
LRRC32 leucine rich repeat containing 32
LTBP1 latent transforming growth factor beta binding protein 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAF1 MAF1 homolog (S. cerevisiae)
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAP2 microtubule-associated protein 2
MAP2K2 mitogen-activated protein kinase kinase 2
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAP6 microtubule-associated protein 6
MAPK1 mitogen-activated protein kinase 1
MAPK12 mitogen-activated protein kinase 12
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MAPT microtubule-associated protein tau
MATR3 matrin 3
MAVS mitochondrial antiviral signaling protein
MBD4 methyl-CpG binding domain protein 4
MBNL1 muscleblind-like splicing regulator 1
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCL1 myeloid cell leukemia 1
MCOLN1 mucolipin 1
MCOLN2 mucolipin 2
MCOLN3 mucolipin 3
MDC1 mediator of DNA-damage checkpoint 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MDM4 MDM4, p53 regulator
MEF2A myocyte enhancer factor 2A
MELK maternal embryonic leucine zipper kinase
MEN1 multiple endocrine neoplasia I
MERTK MER proto-oncogene, tyrosine kinase
MET MET proto-oncogene, receptor tyrosine kinase
MFGE8 milk fat globule-EGF factor 8 protein
MFN2 mitofusin 2
MID1 midline 1
MIR10A microRNA 10a
MIR126 microRNA 126
MIR132 microRNA 132
MIR134 microRNA 134
MIR141 microRNA 141
MIR145 microRNA 145
MIR146A microRNA 146a
MIR155 microRNA 155
MIR15A microRNA 15a
MIR16-1 microRNA 16-1
MIR181A1 microRNA 181a-1
MIR181A2 microRNA 181a-2
MIR183 microRNA 183
MIR1915 microRNA 1915
MIR198 microRNA 198
MIR19A microRNA 19a
MIR200A microRNA 200a
MIR203A microRNA 203a
MIR20A microRNA 20a
MIR221 microRNA 221
MIR222 microRNA 222
MIR24-1 microRNA 24-1
MIR299 microRNA 299
MIR29A microRNA 29a
MIR302A microRNA 302a
MIR30A microRNA 30a
MIR33A microRNA 33a
MIR33B microRNA 33b
MIR34A microRNA 34a
MIR375 microRNA 375
MIR383 microRNA 383
MIR542 microRNA 542
MIR99A microRNA 99a
MITF microphthalmia-associated transcription factor
MME membrane metallo-endopeptidase
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MON2 MON2 homolog (S. cerevisiae)
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MTA1 metastasis associated 1
MTAP methylthioadenosine phosphorylase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTUS1 microtubule associated tumor suppressor 1
MUC1 mucin 1, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
MUS81 MUS81 structure-specific endonuclease subunit
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH1 myosin, heavy chain 1, skeletal muscle, adult
MYH10 myosin, heavy chain 10, non-muscle
MYL2 myosin, light chain 2, regulatory, cardiac, slow
MYLK myosin light chain kinase
MYO5A myosin VA (heavy chain 12, myoxin)
MYO5B myosin VB
MYO5C myosin VC
MYOCD myocardin
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit
NAAA N-acylethanolamine acid amidase
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NCF1C neutrophil cytosolic factor 1C pseudogene
NCK1 NCK adaptor protein 1
NCOA3 nuclear receptor coactivator 3
NDC80 NDC80 kinetochore complex component
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NET1 neuroepithelial cell transforming 1
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFE2L2 nuclear factor, erythroid 2-like 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NKX2-1 NK2 homeobox 1
NLRP3 NLR family, pyrin domain containing 3
NLRP4 NLR family, pyrin domain containing 4
NOD1 nucleotide-binding oligomerization domain containing 1
NOD2 nucleotide-binding oligomerization domain containing 2
NODAL nodal growth differentiation factor
NONO non-POU domain containing, octamer-binding
NOS1 nitric oxide synthase 1 (neuronal)
NOTCH1 notch 1
NOTCH3 notch 3
NOV nephroblastoma overexpressed
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR0B2 nuclear receptor subfamily 0, group B, member 2
NR1H3 nuclear receptor subfamily 1, group H, member 3
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR2C2 nuclear receptor subfamily 2, group C, member 2
NR2E1 nuclear receptor subfamily 2, group E, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR3C2 nuclear receptor subfamily 3, group C, member 2
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NUAK1 NUAK family, SNF1-like kinase, 1
OBFC1 oligonucleotide/oligosaccharide-binding fold containing 1
OBSL1 obscurin-like 1
OCLN occludin
ORAI1 ORAI calcium release-activated calcium modulator 1
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
OXSR1 oxidative stress responsive 1
OXTR oxytocin receptor
P2RX5 purinergic receptor P2X, ligand gated ion channel, 5
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAAF1 proteasomal ATPase-associated factor 1
PABPC1 poly(A) binding protein, cytoplasmic 1
PACS1 phosphofurin acidic cluster sorting protein 1
PARL presenilin associated, rhomboid-like
PARP1 poly (ADP-ribose) polymerase 1
PAX3 paired box 3
PAX5 paired box 5
PAX6 paired box 6
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDCD6IP programmed cell death 6 interacting protein
PDE4B phosphodiesterase 4B, cAMP-specific
PDK2 pyruvate dehydrogenase kinase, isozyme 2
PDLIM2 PDZ and LIM domain 2 (mystique)
PDPK1 3-phosphoinositide dependent protein kinase 1
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PDYN prodynorphin
PEA15 phosphoprotein enriched in astrocytes 15
PECAM1 platelet/endothelial cell adhesion molecule 1
PELP1 proline, glutamate and leucine rich protein 1
PER1 period circadian clock 1
PER2 period circadian clock 2
PES1 pescadillo ribosomal biogenesis factor 1
PGAM1 phosphoglycerate mutase 1 (brain)
PHB2 prohibitin 2
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PI3 peptidase inhibitor 3, skin-derived
PI4KB phosphatidylinositol 4-kinase, catalytic, beta
PIAS3 protein inhibitor of activated STAT, 3
PIAS4 protein inhibitor of activated STAT, 4
PIDD1 p53-induced death domain protein 1
PIGR polymeric immunoglobulin receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIKFYVE phosphoinositide kinase, FYVE finger containing
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKM pyruvate kinase, muscle
PKP4 plakophilin 4
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C, gamma 1
PLEKHO1 pleckstrin homology domain containing, family O member 1
PLIN1 perilipin 1
PLK1 polo-like kinase 1
PML promyelocytic leukemia
PNPLA2 patatin-like phospholipase domain containing 2
PNPLA6 patatin-like phospholipase domain containing 6
POLH polymerase (DNA directed), eta
PPARD peroxisome proliferator-activated receptor delta
PPARG peroxisome proliferator-activated receptor gamma
PPM1A protein phosphatase, Mg2+/Mn2+ dependent, 1A
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1R10 protein phosphatase 1, regulatory subunit 10
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PPP4C protein phosphatase 4, catalytic subunit
PRC1 protein regulator of cytokinesis 1
PRDM1 PR domain containing 1, with ZNF domain
PRDX2 peroxiredoxin 2
PRF1 perforin 1 (pore forming protein)
PRIMA1 proline rich membrane anchor 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKD1 protein kinase D1
PRKRIR protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
PRL prolactin
PRLR prolactin receptor
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROM1 prominin 1
PRPF31 pre-mRNA processing factor 31
PSEN1 presenilin 1
PSEN2 presenilin 2
PSIP1 PC4 and SFRS1 interacting protein 1
PTBP1 polypyrimidine tract binding protein 1
PTEN phosphatase and tensin homolog
PTGDR prostaglandin D2 receptor (DP)
PTGER4 prostaglandin E receptor 4 (subtype EP4)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)
RAB11A RAB11A, member RAS oncogene family
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB1A RAB1A, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAB4A RAB4A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAD18 RAD18 E3 ubiquitin protein ligase
RAD23A RAD23 homolog A (S. cerevisiae)
RAD51 RAD51 recombinase
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAN RAN, member RAS oncogene family
RAP1B RAP1B, member of RAS oncogene family
RARA retinoic acid receptor, alpha
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RBL2 retinoblastoma-like 2
RBX1 ring-box 1, E3 ubiquitin protein ligase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RELN reelin
REST RE1-silencing transcription factor
RGS16 regulator of G-protein signaling 16
RGS19 regulator of G-protein signaling 19
RGS4 regulator of G-protein signaling 4
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOC ras homolog family member C
RILP Rab interacting lysosomal protein
RLN1 relaxin 1
RNF114 ring finger protein 114
RNF125 ring finger protein 125, E3 ubiquitin protein ligase
RNF8 ring finger protein 8, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROCK2 Rho-associated, coiled-coil containing protein kinase 2
ROR2 receptor tyrosine kinase-like orphan receptor 2
RPL11 ribosomal protein L11
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RUNX1 runt-related transcription factor 1
RUNX2 runt-related transcription factor 2
RXRA retinoid X receptor, alpha
SAMHD1 SAM domain and HD domain 1
SATB1 SATB homeobox 1
SDC2 syndecan 2
SDC4 syndecan 4
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SENP8 SUMO/sentrin specific peptidase family member 8
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETD8 SET domain containing (lysine methyltransferase) 8
SFN stratifin
SFPQ splicing factor proline/glutamine-rich
SFTPA1 surfactant protein A1
SGMS1 sphingomyelin synthase 1
SHOX2 short stature homeobox 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SIK1 salt-inducible kinase 1
SIPA1 signal-induced proliferation-associated 1
SIRT1 sirtuin 1
SKA1 spindle and kinetochore associated complex subunit 1
SKA2 spindle and kinetochore associated complex subunit 2
SKA3 spindle and kinetochore associated complex subunit 3
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLAMF1 signaling lymphocytic activation molecule family member 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2
SLC35B3 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLPI secretory leukocyte peptidase inhibitor
SMAD1 SMAD family member 1
SMAD2 SMAD family member 2
SMAD3 SMAD family member 3
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
SMN1 survival of motor neuron 1, telomeric
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SNAPIN SNAP-associated protein
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPB small nuclear ribonucleoprotein polypeptides B and B1
SOCS3 suppressor of cytokine signaling 3
SOD1 superoxide dismutase 1, soluble
SOD3 superoxide dismutase 3, extracellular
SON SON DNA binding protein
SORBS2 sorbin and SH3 domain containing 2
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SOX17 SRY (sex determining region Y)-box 17
SOX2 SRY (sex determining region Y)-box 2
SOX9 SRY (sex determining region Y)-box 9
SP1 Sp1 transcription factor
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPDEF SAM pointed domain containing ETS transcription factor
SPG20 spastic paraplegia 20 (Troyer syndrome)
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPRED2 sprouty-related, EVH1 domain containing 2
SPRY2 sprouty homolog 2 (Drosophila)
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREK1 splicing regulatory glutamine/lysine-rich protein 1
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STGC3 uncharacterized STGC3
STIM1 stromal interaction molecule 1
STIM2 stromal interaction molecule 2
STK11 serine/threonine kinase 11
STK39 serine threonine kinase 39
STMN1 stathmin 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUMO1 small ubiquitin-like modifier 1
SYK spleen tyrosine kinase
SYNPO synaptopodin
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TAOK1 TAO kinase 1
TAS2R38 taste receptor, type 2, member 38
TBCB tubulin folding cofactor B
TBK1 TANK-binding kinase 1
TBP TATA box binding protein
TBX21 T-box 21
TBX5 T-box 5
TDO2 tryptophan 2,3-dioxygenase
TEK TEK tyrosine kinase, endothelial
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TFEB transcription factor EB
TFPT TCF3 (E2A) fusion partner (in childhood Leukemia)
TG thyroglobulin
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGFB3 transforming growth factor, beta 3
TGFBR1 transforming growth factor, beta receptor 1
TGIF1 TGFB-induced factor homeobox 1
THBS1 thrombospondin 1
THPO thrombopoietin
THRAP3 thyroid hormone receptor associated protein 3
TIA1 TIA1 cytotoxic granule-associated RNA binding protein
TIPE2 TNF alpha induced protein 8 like 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR8 toll-like receptor 8
TLR9 toll-like receptor 9
TLX1 T-cell leukemia homeobox 1
TLX3 T-cell leukemia homeobox 3
TMBIM4 transmembrane BAX inhibitor motif containing 4
TMEM106B transmembrane protein 106B
TMPO thymopoietin
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNNI3 troponin I type 3 (cardiac)
TNS4 tensin 4
TOX2 TOX high mobility group box family member 2
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TRA T cell receptor alpha locus
TRD T cell receptor delta locus
TRH thyrotropin-releasing hormone
TRIM28 tripartite motif containing 28
TRIM32 tripartite motif containing 32
TRIM5 tripartite motif containing 5
TRIP10 thyroid hormone receptor interactor 10
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TRPV5 transient receptor potential cation channel, subfamily V, member 5
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TSC2 tuberous sclerosis 2
TSHR thyroid stimulating hormone receptor
TUB tubby bipartite transcription factor
TUBA1A tubulin, alpha 1a
TUBG1 tubulin, gamma 1
TUBGCP5 tubulin, gamma complex associated protein 5
TWIST1 twist family bHLH transcription factor 1
TYRO3 TYRO3 protein tyrosine kinase
UBE3A ubiquitin protein ligase E3A
UBXN6 UBX domain protein 6
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UNC93B1 unc-93 homolog B1 (C. elegans)
USP34 ubiquitin specific peptidase 34
USP44 ubiquitin specific peptidase 44
USP7 ubiquitin specific peptidase 7 (herpes virus-associated)
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VIPR1 vasoactive intestinal peptide receptor 1
VTCN1 V-set domain containing T cell activation inhibitor 1
VTI1B vesicle transport through interaction with t-SNAREs 1B
VWF von Willebrand factor
WASF1 WAS protein family, member 1
WASF3 WAS protein family, member 3
WEE1 WEE1 G2 checkpoint kinase
WIPI1 WD repeat domain, phosphoinositide interacting 1
WNT5A wingless-type MMTV integration site family, member 5A
WT1 Wilms tumor 1
WTAP Wilms tumor 1 associated protein
XBP1 X-box binding protein 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
YAP1 Yes-associated protein 1
YBX1 Y box binding protein 1
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
ZBTB20 zinc finger and BTB domain containing 20
ZBTB38 zinc finger and BTB domain containing 38
ZC3HC1 zinc finger, C3HC-type containing 1
ZEB1 zinc finger E-box binding homeobox 1
ZEB2 zinc finger E-box binding homeobox 2
ZFP36 ZFP36 ring finger protein
ZNF143 zinc finger protein 143