convolamine-1779 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

200 genes differentially expressed following the convolamine-1779 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT7 acyl-CoA thioesterase 7
APC adenomatous polyposis coli
ARHGAP1 Rho GTPase activating protein 1
ARPC4 actin related protein 2/3 complex, subunit 4, 20kDa
ARRB2 arrestin, beta 2
ATP5G2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
BATF3 basic leucine zipper transcription factor, ATF-like 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
BTBD18 BTB (POZ) domain containing 18
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CADM3 cell adhesion molecule 3
CARD9 caspase recruitment domain family, member 9
CBX6 chromobox homolog 6
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDHR2 cadherin-related family member 2
COL10A1 collagen, type X, alpha 1
COL7A1 collagen, type VII, alpha 1
CPNE1 copine I
CYB561 cytochrome b561
DBF4B DBF4 zinc finger B
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4
DOCK4 dedicator of cytokinesis 4
EFR3B EFR3 homolog B (S. cerevisiae)
ELMO2 engulfment and cell motility 2
FBXO46 F-box protein 46
FKBP15 FK506 binding protein 15, 133kDa
FLNC filamin C, gamma
FMOD fibromodulin
GCDH glutaryl-CoA dehydrogenase
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GOSR2 golgi SNAP receptor complex member 2
GPR107 G protein-coupled receptor 107
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX2 glutathione peroxidase 2
GSK3A glycogen synthase kinase 3 alpha
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HACD3 3-hydroxyacyl-CoA dehydratase 3
HBB hemoglobin, beta
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HRH1 histamine receptor H1
HYAL2 hyaluronoglucosaminidase 2
IFT27 intraflagellar transport 27
IGKV1D-13 immunoglobulin kappa variable 1D-13
ING4 inhibitor of growth family, member 4
IQSEC1 IQ motif and Sec7 domain 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGA7 integrin, alpha 7
ITGB5 integrin, beta 5
KIR2DL4 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4
KRTAP1-1 keratin associated protein 1-1
LARP1 La ribonucleoprotein domain family, member 1
LAT2 linker for activation of T cells family, member 2
LPAR3 lysophosphatidic acid receptor 3
MANEA mannosidase, endo-alpha
MB myoglobin
MPV17 MpV17 mitochondrial inner membrane protein
MVK mevalonate kinase
NRIP3 nuclear receptor interacting protein 3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR2H2 olfactory receptor, family 2, subfamily H, member 2
ORC4 origin recognition complex, subunit 4
PCSK6 proprotein convertase subtilisin/kexin type 6
PIGV phosphatidylinositol glycan anchor biosynthesis, class V
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PILRB paired immunoglobin-like type 2 receptor beta
PKN1 protein kinase N1
PLD2 phospholipase D2
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPIEL peptidylprolyl isomerase E-like pseudogene
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PTMA prothymosin, alpha
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RANBP10 RAN binding protein 10
RFK riboflavin kinase
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL18 ribosomal protein L18
SAPCD1 suppressor APC domain containing 1
SCD5 stearoyl-CoA desaturase 5
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SKAP1 src kinase associated phosphoprotein 1
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC38A6 solute carrier family 38, member 6
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SYNGR1 synaptogyrin 1
TADA2A transcriptional adaptor 2A
TGM5 transglutaminase 5
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM127 transmembrane protein 127
TMEM159 transmembrane protein 159
TOX4 TOX high mobility group box family member 4
TPMT thiopurine S-methyltransferase
TRIM16 tripartite motif containing 16
TSHB thyroid stimulating hormone, beta
TUBB3 tubulin, beta 3 class III
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
ZNF142 zinc finger protein 142

decreased expression

Symbol Name
AP1G2 adaptor-related protein complex 1, gamma 2 subunit
ARID4A AT rich interactive domain 4A (RBP1-like)
ASF1B anti-silencing function 1B histone chaperone
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
C5ORF28 chromosome 5 open reading frame 28
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3
CEND1 cell cycle exit and neuronal differentiation 1
CERS2 ceramide synthase 2
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CHST4 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4
CISH cytokine inducible SH2-containing protein
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase
COPS7B COP9 signalosome subunit 7B
DEXI Dexi homolog (mouse)
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAAF2 dynein, axonemal, assembly factor 2
DNAJC11 DnaJ (Hsp40) homolog, subfamily C, member 11
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
ERCC3 excision repair cross-complementation group 3
FADS2 fatty acid desaturase 2
FAM189B family with sequence similarity 189, member B
FAM50A family with sequence similarity 50, member A
FGF4 fibroblast growth factor 4
FNBP4 formin binding protein 4
FOXM1 forkhead box M1
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GATAD2A GATA zinc finger domain containing 2A
GBAS glioblastoma amplified sequence
GCHFR GTP cyclohydrolase I feedback regulator
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLMN glomulin, FKBP associated protein
GLRX2 glutaredoxin 2
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GPRC5C G protein-coupled receptor, class C, group 5, member C
GTF2I general transcription factor IIi
H2BFS H2B histone family, member S (pseudogene)
HINFP histone H4 transcription factor
INTS9 integrator complex subunit 9
IP6K1 inositol hexakisphosphate kinase 1
IRF1 interferon regulatory factor 1
ITGAV integrin, alpha V
ITPKC inositol-trisphosphate 3-kinase C
KDM7A lysine (K)-specific demethylase 7A
KIAA0894 KIAA0894 protein
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRBOX4 KRAB box domain containing 4
KRI1 KRI1 homolog (S. cerevisiae)
LGALS9 lectin, galactoside-binding, soluble, 9
LUC7L LUC7-like (S. cerevisiae)
MAVS mitochondrial antiviral signaling protein
MBIP MAP3K12 binding inhibitory protein 1
MFF mitochondrial fission factor
MOCOS molybdenum cofactor sulfurase
MOCS2 molybdenum cofactor synthesis 2
MON1B MON1 secretory trafficking family member B
MORC3 MORC family CW-type zinc finger 3
MPP1 membrane protein, palmitoylated 1, 55kDa
NOC2L nucleolar complex associated 2 homolog (S. cerevisiae)
NRBP1 nuclear receptor binding protein 1
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1
PNRC1 proline-rich nuclear receptor coactivator 1
POGLUT1 protein O-glucosyltransferase 1
POTEKP POTE ankyrin domain family, member K, pseudogene
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP6R1 protein phosphatase 6, regulatory subunit 1
RAB1B RAB1B, member RAS oncogene family
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1
RWDD3 RWD domain containing 3
SDF2L1 stromal cell-derived factor 2-like 1
SDHAF3 succinate dehydrogenase complex assembly factor 3
SECISBP2L SECIS binding protein 2-like
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIRT7 sirtuin 7
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SNAP29 synaptosomal-associated protein, 29kDa
SSFA2 sperm specific antigen 2
TCTN2 tectonic family member 2
TM7SF2 transmembrane 7 superfamily member 2
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM184B transmembrane protein 184B
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TPBG trophoblast glycoprotein
TRIM22 tripartite motif containing 22
USP8 ubiquitin specific peptidase 8
UTP20 UTP20, small subunit (SSU) processome component, homolog (yeast)
VILL villin-like
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae)
XDH xanthine dehydrogenase
ZC3H3 zinc finger CCCH-type containing 3
ZNF140 zinc finger protein 140
ZNF212 zinc finger protein 212
ZNF529 zinc finger protein 529
ZNF767P zinc finger family member 767, pseudogene