convolamine-2771 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the convolamine-2771 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABI2 abl-interactor 2
ACAA2 acetyl-CoA acyltransferase 2
ACVR1B activin A receptor, type IB
AKAP8L A kinase (PRKA) anchor protein 8-like
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANKRD12 ankyrin repeat domain 12
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ASPH aspartate beta-hydroxylase
ATF7IP activating transcription factor 7 interacting protein
BAX BCL2-associated X protein
BMP10 bone morphogenetic protein 10
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF30 chromosome 11 open reading frame 30
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CDC42 cell division cycle 42
DCAF7 DDB1 and CUL4 associated factor 7
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DIS3 DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DMXL2 Dmx-like 2
DTNA dystrobrevin, alpha
E2F4 E2F transcription factor 4, p107/p130-binding
EGLN3 egl-9 family hypoxia-inducible factor 3
EML2 echinoderm microtubule associated protein like 2
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FADS2 fatty acid desaturase 2
FCF1 FCF1 rRNA-processing protein
FTCD formimidoyltransferase cyclodeaminase
GRAMD1C GRAM domain containing 1C
HAP1 huntingtin-associated protein 1
HCRP1 hepatocellular carcinoma-related HCRP1
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H3B histone cluster 1, H3b
HIST1H4E histone cluster 1, H4e
HLA-DMA major histocompatibility complex, class II, DM alpha
IDS iduronate 2-sulfatase
IL11 interleukin 11
KAZN kazrin, periplakin interacting protein
KHK ketohexokinase (fructokinase)
KLHL22 kelch-like family member 22
LMAN1 lectin, mannose-binding, 1
LMNB1 lamin B1
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LTBP4 latent transforming growth factor beta binding protein 4
MAP2K5 mitogen-activated protein kinase kinase 5
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2
MBTD1 mbt domain containing 1
MR1 major histocompatibility complex, class I-related
NEK9 NIMA-related kinase 9
NF2 neurofibromin 2 (merlin)
NPY1R neuropeptide Y receptor Y1
NR4A1 nuclear receptor subfamily 4, group A, member 1
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE3B phosphodiesterase 3B, cGMP-inhibited
PDLIM7 PDZ and LIM domain 7 (enigma)
PHTF2 putative homeodomain transcription factor 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLAU plasminogen activator, urokinase
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRMT2 protein arginine methyltransferase 2
RAB35 RAB35, member RAS oncogene family
RAB40C RAB40C, member RAS oncogene family
RNMT RNA (guanine-7-) methyltransferase
SCAI suppressor of cancer cell invasion
SH3GL3 SH3-domain GRB2-like 3
SHANK2 SH3 and multiple ankyrin repeat domains 2
SHOX2 short stature homeobox 2
SIDT2 SID1 transmembrane family, member 2
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SMAD5 SMAD family member 5
SNRK SNF related kinase
SOS2 son of sevenless homolog 2 (Drosophila)
SPTAN1 spectrin, alpha, non-erythrocytic 1
STMN1 stathmin 1
SUN1 Sad1 and UNC84 domain containing 1
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
THAP9 THAP domain containing 9
TMEM45A transmembrane protein 45A
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TRIM36 tripartite motif containing 36
TTLL4 tubulin tyrosine ligase-like family member 4
TYRO3 TYRO3 protein tyrosine kinase
VEGFA vascular endothelial growth factor A
WDR55 WD repeat domain 55
ZBTB6 zinc finger and BTB domain containing 6
ZCCHC14 zinc finger, CCHC domain containing 14
ZDHHC14 zinc finger, DHHC-type containing 14
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP64 ZFP64 zinc finger protein

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACTL8 actin-like 8
AHDC1 AT hook, DNA binding motif, containing 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALDOC aldolase C, fructose-bisphosphate
AMPD1 adenosine monophosphate deaminase 1
ARMC4 armadillo repeat containing 4
ARMCX2 armadillo repeat containing, X-linked 2
ASIC3 acid sensing (proton gated) ion channel 3
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL9 B-cell CLL/lymphoma 9
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF73 chromosome 19 open reading frame 73
C2ORF54 chromosome 2 open reading frame 54
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CD53 CD53 molecule
CIDEB cell death-inducing DFFA-like effector b
CORT cortistatin
CPPED1 calcineurin-like phosphoesterase domain containing 1
CRELD1 cysteine-rich with EGF-like domains 1
CTC1 CTS telomere maintenance complex component 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DIXDC1 DIX domain containing 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DSCAM Down syndrome cell adhesion molecule
DUSP13 dual specificity phosphatase 13
DVL1 dishevelled segment polarity protein 1
FAM76A family with sequence similarity 76, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
FGL1 fibrinogen-like 1
FLJ11710 uncharacterized protein FLJ11710
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFI1 growth factor independent 1 transcription repressor
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
HLA-J major histocompatibility complex, class I, J (pseudogene)
HOXA4 homeobox A4
HOXC11 homeobox C11
HOXC5 homeobox C5
IL12RB1 interleukin 12 receptor, beta 1
IL4R interleukin 4 receptor
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KDM5C lysine (K)-specific demethylase 5C
KEL Kell blood group, metallo-endopeptidase
KLK5 kallikrein-related peptidase 5
KRI1 KRI1 homolog (S. cerevisiae)
KRT13 keratin 13, type I
LARP6 La ribonucleoprotein domain family, member 6
LRRC61 leucine rich repeat containing 61
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MEFV Mediterranean fever
MGC12488
MITF microphthalmia-associated transcription factor
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MMP2 matrix metallopeptidase 2
NCALD neurocalcin delta
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NOL10 nucleolar protein 10
NPFFR1 neuropeptide FF receptor 1
ONECUT2 one cut homeobox 2
PGR progesterone receptor
PHEX phosphate regulating endopeptidase homolog, X-linked
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PLCD1 phospholipase C, delta 1
PTPRU protein tyrosine phosphatase, receptor type, U
RIN2 Ras and Rab interactor 2
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RPAP1 RNA polymerase II associated protein 1
S100A2 S100 calcium binding protein A2
SECTM1 secreted and transmembrane 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD1A SET domain containing 1A
SLC22A14 solute carrier family 22, member 14
SPON2 spondin 2, extracellular matrix protein
STK16 serine/threonine kinase 16
STXBP2 syntaxin binding protein 2
TCP10 t-complex 10
TEAD3 TEA domain family member 3
TESC tescalcin
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNS2 tensin 2
TTLL1 tubulin tyrosine ligase-like family member 1
TUBG2 tubulin, gamma 2
USP20 ubiquitin specific peptidase 20
XYLT2 xylosyltransferase II
ZBTB22 zinc finger and BTB domain containing 22
ZBTB48 zinc finger and BTB domain containing 48
ZC3H3 zinc finger CCCH-type containing 3
ZNF639 zinc finger protein 639
ZSCAN31 zinc finger and SCAN domain containing 31