cop9 signalosome Gene Set

Dataset GO Cellular Component Annotations 2015
Category structural or functional annotations
Type cellular component
Description A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome. (Gene Ontology, GO_0008180)
External Link http://amigo.geneontology.org/amigo/term/GO:0008180
Similar Terms
Downloads & Tools

Genes

33 proteins localized to the cop9 signalosome cellular component from the curated GO Cellular Component Annotations 2015 dataset.

Symbol Name
AMOT angiomotin
AMOTL1 angiomotin like 1
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
BASP1 brain abundant, membrane attached signal protein 1
COPS2 COP9 signalosome subunit 2
COPS3 COP9 signalosome subunit 3
COPS4 COP9 signalosome subunit 4
COPS5 COP9 signalosome subunit 5
COPS6 COP9 signalosome subunit 6
COPS7A COP9 signalosome subunit 7A
COPS7B COP9 signalosome subunit 7B
COPS8 COP9 signalosome subunit 8
DOCK7 dedicator of cytokinesis 7
DYNLL1 dynein, light chain, LC8-type 1
EPB41L2 erythrocyte membrane protein band 4.1-like 2
FLOT1 flotillin 1
GPS1 G protein pathway suppressor 1
GRB2 growth factor receptor-bound protein 2
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA1L heat shock 70kDa protein 1-like
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
LAT linker for activation of T cells
MYH9 myosin, heavy chain 9, non-muscle
NCKIPSD NCK interacting protein with SH3 domain
NOD2 nucleotide-binding oligomerization domain containing 2
PLCG1 phospholipase C, gamma 1
STOML2 stomatin (EPB72)-like 2
TESPA1 thymocyte expressed, positive selection associated 1
THEMIS thymocyte selection associated
TMOD1 tropomodulin 1
VPRBP Vpr (HIV-1) binding protein
WDR6 WD repeat domain 6