cornification Gene Set

Dataset GO Biological Process Annotations 2015
Category structural or functional annotations
Type biological process
Description A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability). (Gene Ontology, GO_0070268)
External Link http://amigo.geneontology.org/amigo/term/GO:0070268
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Genes

3 genes participating in the cornification biological process from the curated GO Biological Process Annotations 2015 dataset.

Symbol Name
CASP14 caspase 14, apoptosis-related cysteine peptidase
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1
TMEM79 transmembrane protein 79