cornified envelope Gene Set

Dataset GO Cellular Component Annotations 2025
Category structural or functional annotations
Type cellular component
Description A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes). (Gene Ontology, GO_0001533)
External Link http://amigo.geneontology.org/amigo/term/GO:0001533
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Genes

43 proteins localized to the cornified envelope cellular component from the curated GO Cellular Component Annotations 2025 dataset.

Symbol Name
ANXA1 annexin A1
CDSN corneodesmosin
CNFN cornifelin
CSTA cystatin A (stefin A)
CYSRT1 cysteine-rich tail protein 1
DSC3 desmocollin 3
DSG1 desmoglein 1
DSG2 desmoglein 2
DSG3 desmoglein 3
DSG4 desmoglein 4
DSPP dentin sialophosphoprotein
EVPL envoplakin
FLG filaggrin
FLG2 filaggrin family member 2
HRNR hornerin
IVL involucrin
JUP junction plakoglobin
KAZN kazrin, periplakin interacting protein
KRT1 keratin 1, type II
KRT10 keratin 10, type I
KRT2 keratin 2, type II
LCE1D late cornified envelope 1D
LORICRIN loricrin cornified envelope precursor protein
PI3 peptidase inhibitor 3, skin-derived
PKP1 plakophilin 1
PKP2 plakophilin 2
PKP3 plakophilin 3
PKP4 plakophilin 4
PPL periplakin
RCAN1 regulator of calcineurin 1
RPTN repetin
SCEL sciellin
SPRR1A small proline-rich protein 1A
SPRR1B small proline-rich protein 1B
SPRR2A small proline-rich protein 2A
SPRR2B small proline-rich protein 2B
SPRR2D small proline-rich protein 2D
SPRR2E small proline-rich protein 2E
SPRR2F small proline-rich protein 2F
SPRR2G small proline-rich protein 2G
SPRR3 small proline-rich protein 3
TCHH trichohyalin
TGM1 transglutaminase 1