cortical Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Cortex of kidney. (BRENDA Tissue and Enzyme Source Ontology, BTO_0001166)
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Genes

373 genes co-occuring with the biological term cortical in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ACAN aggrecan
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ACMSD aminocarboxymuconate semialdehyde decarboxylase
ACTN1 actinin, alpha 1
ADAM10 ADAM metallopeptidase domain 10
ADAM15 ADAM metallopeptidase domain 15
ADGRG1 adhesion G protein-coupled receptor G1
ADM adrenomedullin
ADORA1 adenosine A1 receptor
ADRA2B adrenoceptor alpha 2B
ADRBK1 adrenergic, beta, receptor kinase 1
ADRBK2 adrenergic, beta, receptor kinase 2
AHI1 Abelson helper integration site 1
AIRE autoimmune regulator
AKAP12 A kinase (PRKA) anchor protein 12
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALPL alkaline phosphatase, liver/bone/kidney
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
ANKK1 ankyrin repeat and kinase domain containing 1
ANXA6 annexin A6
APC adenomatous polyposis coli
APOB apolipoprotein B
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
AQP4 aquaporin 4
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18
ARTN artemin
ASIC1 acid sensing (proton gated) ion channel 1
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATXN7 ataxin 7
AVPR2 arginine vasopressin receptor 2
B3GAT2 beta-1,3-glucuronyltransferase 2
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BCHE butyrylcholinesterase
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein)
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
C5AR1 complement component 5a receptor 1
C9ORF72 chromosome 9 open reading frame 72
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CADM1 cell adhesion molecule 1
CALB1 calbindin 1, 28kDa
CALB2 calbindin 2
CAMK1G calcium/calmodulin-dependent protein kinase IG
CAPN1 calpain 1, (mu/I) large subunit
CAPN2 calpain 2, (m/II) large subunit
CCL2 chemokine (C-C motif) ligand 2
CCNA2 cyclin A2
CCNB1 cyclin B1
CCND2 cyclin D2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDK1 cyclin-dependent kinase 1
CDK2 cyclin-dependent kinase 2
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CFL1 cofilin 1 (non-muscle)
CHAT choline O-acetyltransferase
CHRM1 cholinergic receptor, muscarinic 1
CHRM3 cholinergic receptor, muscarinic 3
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLASP2 cytoplasmic linker associated protein 2
CLIC5 chloride intracellular channel 5
CLMP CXADR-like membrane protein
CMA1 chymase 1, mast cell
CNGA1 cyclic nucleotide gated channel alpha 1
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CNTNAP2 contactin associated protein-like 2
COL1A1 collagen, type I, alpha 1
COMT catechol-O-methyltransferase
CPLX2 complexin 2
CRHBP corticotropin releasing hormone binding protein
CRYAA crystallin, alpha A
CRYBA1 crystallin, beta A1
CTNND2 catenin (cadherin-associated protein), delta 2
CUL5 cullin 5
CXCR4 chemokine (C-X-C motif) receptor 4
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DAGLA diacylglycerol lipase, alpha
DAOA D-amino acid oxidase activator
DHPS deoxyhypusine synthase
DIAPH3 diaphanous-related formin 3
DISC1 disrupted in schizophrenia 1
DIXDC1 DIX domain containing 1
DLG3 discs, large homolog 3 (Drosophila)
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DLX1 distal-less homeobox 1
DLX2 distal-less homeobox 2
DRD1 dopamine receptor D1
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
DTNBP1 dystrobrevin binding protein 1
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYX1C1 dyslexia susceptibility 1 candidate 1
ECE1 endothelin converting enzyme 1
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EMX2 empty spiracles homeobox 2
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPAS1 endothelial PAS domain protein 1
EPB41 erythrocyte membrane protein band 4.1
EPHA2 EPH receptor A2
EPOR erythropoietin receptor
ERBB4 erb-b2 receptor tyrosine kinase 4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ERN1 endoplasmic reticulum to nucleus signaling 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM134C family with sequence similarity 134, member C
FASLG Fas ligand (TNF superfamily, member 6)
FGF2 fibroblast growth factor 2 (basic)
FIG4 FIG4 phosphoinositide 5-phosphatase
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXP2 forkhead box P2
FYN FYN proto-oncogene, Src family tyrosine kinase
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GABRD gamma-aminobutyric acid (GABA) A receptor, delta
GAD1 glutamate decarboxylase 1 (brain, 67kDa)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GBA glucosidase, beta, acid
GDNF glial cell derived neurotrophic factor
GEM GTP binding protein overexpressed in skeletal muscle
GLI3 GLI family zinc finger 3
GMIP GEM interacting protein
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
GPSM1 G-protein signaling modulator 1
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GRK5 G protein-coupled receptor kinase 5
GRK6 G protein-coupled receptor kinase 6
GRM1 glutamate receptor, metabotropic 1
GRM3 glutamate receptor, metabotropic 3
GRM5 glutamate receptor, metabotropic 5
GRN granulin
GSK3A glycogen synthase kinase 3 alpha
GSK3B glycogen synthase kinase 3 beta
GSTM1 glutathione S-transferase mu 1
GSTT1 glutathione S-transferase theta 1
GUCA2A guanylate cyclase activator 2A (guanylin)
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HDGFRP3 hepatoma-derived growth factor, related protein 3
HES6 hes family bHLH transcription factor 6
HIPK2 homeodomain interacting protein kinase 2
HSPA12A heat shock 70kDa protein 12A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTT huntingtin
ICAM1 intercellular adhesion molecule 1
IDE insulin-degrading enzyme
IFITM1 interferon induced transmembrane protein 1
IFNB1 interferon, beta 1, fibroblast
IFNG interferon, gamma
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL2 interleukin 2
IL3 interleukin 3
INS insulin
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
ITGA6 integrin, alpha 6
ITGAV integrin, alpha V
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUN jun proto-oncogene
KATNB1 katanin p80 (WD repeat containing) subunit B 1
KCND1 potassium channel, voltage gated Shal related subfamily D, member 1
KCND2 potassium channel, voltage gated Shal related subfamily D, member 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KITLG KIT ligand
LAMC3 laminin, gamma 3
LIAS lipoic acid synthetase
LIMK1 LIM domain kinase 1
LIN7B lin-7 homolog B (C. elegans)
LLGL1 lethal giant larvae homolog 1 (Drosophila)
LRP5 low density lipoprotein receptor-related protein 5
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MECP2 methyl CpG binding protein 2
MICA MHC class I polypeptide-related sequence A
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR128-1 microRNA 128-1
MIR137 microRNA 137
MIR483 microRNA 483
MISP mitotic spindle positioning
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRNR2L1 MT-RNR2-like 1
MYO5A myosin VA (heavy chain 12, myoxin)
MYRIP myosin VIIA and Rab interacting protein
NCAM1 neural cell adhesion molecule 1
NCAN neurocan
NDE1 nudE neurodevelopment protein 1
NDRG2 NDRG family member 2
NF2 neurofibromin 2 (merlin)
NGF nerve growth factor (beta polypeptide)
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
NPAS3 neuronal PAS domain protein 3
NPY neuropeptide Y
NR0B1 nuclear receptor subfamily 0, group B, member 1
NR2E1 nuclear receptor subfamily 2, group E, member 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRF1 nuclear respiratory factor 1
NRG1 neuregulin 1
NRTN neurturin
NTN1 netrin 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
NTRK3 neurotrophic tyrosine kinase, receptor, type 3
NUMA1 nuclear mitotic apparatus protein 1
OCLN occludin
OGG1 8-oxoguanine DNA glycosylase
OPRM1 opioid receptor, mu 1
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PARK2 parkin RBR E3 ubiquitin protein ligase
PAX6 paired box 6
PCDH12 protocadherin 12
PDE8B phosphodiesterase 8B
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPK1 3-phosphoinositide dependent protein kinase 1
PHLDB2 pleckstrin homology-like domain, family B, member 2
PINK1 PTEN induced putative kinase 1
PLA2G3 phospholipase A2, group III
PLAT plasminogen activator, tissue
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLEC plectin
PLK1 polo-like kinase 1
POLG polymerase (DNA directed), gamma
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PPP4C protein phosphatase 4, catalytic subunit
PREP prolyl endopeptidase
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKCB protein kinase C, beta
PRKCZ protein kinase C, zeta
PRNP prion protein
PRODH proline dehydrogenase (oxidase) 1
PROM1 prominin 1
PSEN1 presenilin 1
PSMB11 proteasome (prosome, macropain) subunit, beta type, 11
PSPN persephin
PTEN phosphatase and tensin homolog
PTGFR prostaglandin F receptor (FP)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTHLH parathyroid hormone-like hormone
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PVALB parvalbumin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RACGAP1 Rac GTPase activating protein 1
RAP1A RAP1A, member of RAS oncogene family
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RELN reelin
RGS4 regulator of G-protein signaling 4
RHOA ras homolog family member A
RHOQ ras homolog family member Q
RIC8A RIC8 guanine nucleotide exchange factor A
RNASE4 ribonuclease, RNase A family, 4
RPS6 ribosomal protein S6
RTN4 reticulon 4
RTN4R reticulon 4 receptor
S1PR1 sphingosine-1-phosphate receptor 1
SAA1 serum amyloid A1
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN3A sodium channel, voltage gated, type III alpha subunit
SEPT2 septin 2
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SH2B3 SH2B adaptor protein 3
SHBG sex hormone-binding globulin
SHOX short stature homeobox
SIGMAR1 sigma non-opioid intracellular receptor 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD4 SMAD family member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNCB synuclein, beta
SOD1 superoxide dismutase 1, soluble
SOST sclerostin
SOX6 SRY (sex determining region Y)-box 6
SPAST spastin
SPG11 spastic paraplegia 11 (autosomal recessive)
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SST somatostatin
SSTR2 somatostatin receptor 2
STIM1 stromal interaction molecule 1
STON2 stonin 2
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
STX8 syntaxin 8
SUMO1 small ubiquitin-like modifier 1
SV2A synaptic vesicle glycoprotein 2A
SYP synaptophysin
SYPL1 synaptophysin-like 1
SYTL1 synaptotagmin-like 1
SYTL2 synaptotagmin-like 2
TAC1 tachykinin, precursor 1
TACR1 tachykinin receptor 1
TARDBP TAR DNA binding protein
TDRD7 tudor domain containing 7
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TIAM1 T-cell lymphoma invasion and metastasis 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLX1 T-cell leukemia homeobox 1
TLX3 T-cell leukemia homeobox 3
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNR tenascin R
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53 tumor protein p53
TPH2 tryptophan hydroxylase 2
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TSHR thyroid stimulating hormone receptor
TUBA1A tubulin, alpha 1a
TUBB2B tubulin, beta 2B class IIb
TUBB3 tubulin, beta 3 class III
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UNC5B unc-5 homolog B (C. elegans)
VASP vasodilator-stimulated phosphoprotein
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VLDLR very low density lipoprotein receptor
WDR62 WD repeat domain 62
WNT16 wingless-type MMTV integration site family, member 16
WRN Werner syndrome, RecQ helicase-like
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XK X-linked Kx blood group
ZDHHC8 zinc finger, DHHC-type containing 8
ZEB2 zinc finger E-box binding homeobox 2
ZFYVE26 zinc finger, FYVE domain containing 26
ZNF804A zinc finger protein 804A