corynanthine-2786 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the corynanthine-2786 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKAP7 A kinase (PRKA) anchor protein 7
APOE apolipoprotein E
ARC activity-regulated cytoskeleton-associated protein
ASIC3 acid sensing (proton gated) ion channel 3
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAIAP3 BAI1-associated protein 3
BLVRA biliverdin reductase A
BMP1 bone morphogenetic protein 1
BMP5 bone morphogenetic protein 5
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CALCOCO1 calcium binding and coiled-coil domain 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CAV2 caveolin 2
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2
CD34 CD34 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLPS colipase, pancreatic
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNTNAP1 contactin associated protein 1
COL6A3 collagen, type VI, alpha 3
COMP cartilage oligomeric matrix protein
CPQ carboxypeptidase Q
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CTNS cystinosin, lysosomal cystine transporter
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPS15L1 epidermal growth factor receptor pathway substrate 15-like 1
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM182B family with sequence similarity 182, member B
FAM50B family with sequence similarity 50, member B
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2
FXYD5 FXYD domain containing ion transport regulator 5
GDF5 growth differentiation factor 5
GFER growth factor, augmenter of liver regeneration
GPR1 G protein-coupled receptor 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GSTP1 glutathione S-transferase pi 1
HUS1 HUS1 checkpoint homolog (S. pombe)
ICA1 islet cell autoantigen 1, 69kDa
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ITGA10 integrin, alpha 10
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1
KCNN1 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1
KDM4B lysine (K)-specific demethylase 4B
KRT2 keratin 2, type II
LAMC2 laminin, gamma 2
MAPT microtubule-associated protein tau
MCPH1 microcephalin 1
MLN motilin
MYL10 myosin, light chain 10, regulatory
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NTF3 neurotrophin 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
PARVB parvin, beta
PGBD5 piggyBac transposable element derived 5
PLAGL1 pleiomorphic adenoma gene-like 1
PLK3 polo-like kinase 3
POFUT1 protein O-fucosyltransferase 1
POM121 POM121 transmembrane nucleoporin
POPDC3 popeye domain containing 3
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPP5C protein phosphatase 5, catalytic subunit
PRKACG protein kinase, cAMP-dependent, catalytic, gamma
PSG3 pregnancy specific beta-1-glycoprotein 3
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
RAD54L2 RAD54-like 2 (S. cerevisiae)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RELN reelin
RGS2 regulator of G-protein signaling 2
RHEB Ras homolog enriched in brain
RPS4Y1 ribosomal protein S4, Y-linked 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEC24D SEC24 family member D
SECTM1 secreted and transmembrane 1
SH3BP2 SH3-domain binding protein 2
SIRT5 sirtuin 5
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SMAD6 SMAD family member 6
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYN2 synapsin II
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TK2 thymidine kinase 2, mitochondrial
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPM3 tropomyosin 3
TRMT1 tRNA methyltransferase 1 homolog (S. cerevisiae)
TTC39A tetratricopeptide repeat domain 39A
WAS Wiskott-Aldrich syndrome
WSCD1 WSC domain containing 1
ZC3H13 zinc finger CCCH-type containing 13
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L1 ZFP36 ring finger protein-like 1
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ACSL4 acyl-CoA synthetase long-chain family member 4
ADCY7 adenylate cyclase 7
AHNAK2 AHNAK nucleoprotein 2
ANKRD40 ankyrin repeat domain 40
ATF7IP2 activating transcription factor 7 interacting protein 2
B9D2 B9 protein domain 2
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF80 chromosome 17 open reading frame 80
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5AR2 complement component 5a receptor 2
CA11 carbonic anhydrase XI
CASZ1 castor zinc finger 1
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CHKB choline kinase beta
CLCN6 chloride channel, voltage-sensitive 6
CLDN9 claudin 9
CLIC3 chloride intracellular channel 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
CRELD1 cysteine-rich with EGF-like domains 1
CSTA cystatin A (stefin A)
CUEDC1 CUE domain containing 1
DGKE diacylglycerol kinase, epsilon 64kDa
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM188A family with sequence similarity 188, member A
FGD1 FYVE, RhoGEF and PH domain containing 1
GLCE glucuronic acid epimerase
GLI3 GLI family zinc finger 3
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
GPATCH2L G patch domain containing 2-like
GPRASP1 G protein-coupled receptor associated sorting protein 1
GUSBP3 glucuronidase, beta pseudogene 3
HIST1H2AJ histone cluster 1, H2aj
HIST1H3E histone cluster 1, H3e
HMOX1 heme oxygenase 1
HPSE heparanase
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFT22 intraflagellar transport 22
LGMN legumain
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP5L low density lipoprotein receptor-related protein 5-like
MAST3 microtubule associated serine/threonine kinase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCC mutated in colorectal cancers
MED15 mediator complex subunit 15
MITF microphthalmia-associated transcription factor
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
NFE2L3 nuclear factor, erythroid 2-like 3
NIPAL2 NIPA-like domain containing 2
NPY1R neuropeptide Y receptor Y1
NXPE3 neurexophilin and PC-esterase domain family, member 3
OLFML3 olfactomedin-like 3
PCBP4 poly(rC) binding protein 4
PCDHA6 protocadherin alpha 6
PCDHB3 protocadherin beta 3
PDLIM2 PDZ and LIM domain 2 (mystique)
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RGS19 regulator of G-protein signaling 19
RNF113A ring finger protein 113A
RNF121 ring finger protein 121
RPL23AP32 ribosomal protein L23a pseudogene 32
SCAI suppressor of cancer cell invasion
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SETD1A SET domain containing 1A
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPIDR scaffolding protein involved in DNA repair
SYT17 synaptotagmin XVII
TCTA T-cell leukemia translocation altered
TMEM62 transmembrane protein 62
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRABD TraB domain containing
TSSC4 tumor suppressing subtransferable candidate 4
TTBK2 tau tubulin kinase 2
TTC13 tetratricopeptide repeat domain 13
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
XKR8 XK, Kell blood group complex subunit-related family, member 8
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF204P zinc finger protein 204, pseudogene
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF7 zinc finger protein 7
ZNF862 zinc finger protein 862