costello syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [SN]. (Human Disease Ontology, DOID_0050469)
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Genes

44 genes co-occuring with the disease costello syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HRAS Harvey rat sarcoma viral oncogene homolog 2.14175
MAP2K2 mitogen-activated protein kinase kinase 2 1.78263
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.67367
MAP2K1 mitogen-activated protein kinase kinase 1 1.65879
SOS1 son of sevenless homolog 1 (Drosophila) 1.47594
SHOC2 soc-2 suppressor of clear homolog (C. elegans) 1.2813
ELN elastin 1.23733
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.962891
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.915139
NF1 neurofibromin 1 0.905675
GRIP1 glutamate receptor interacting protein 1 0.793771
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1 0.776977
RALGDS ral guanine nucleotide dissociation stimulator 0.765943
MFAP2 microfibrillar-associated protein 2 0.763494
FGFR3 fibroblast growth factor receptor 3 0.711587
LAX1 lymphocyte transmembrane adaptor 1 0.641039
SPRED1 sprouty-related, EVH1 domain containing 1 0.635135
ZHX2 zinc fingers and homeoboxes 2 0.564889
PDGFD platelet derived growth factor D 0.542767
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.537344
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.518034
FBLN5 fibulin 5 0.513417
PDGFC platelet derived growth factor C 0.502292
MAGEA4 melanoma antigen family A4 0.493885
KRAS Kirsten rat sarcoma viral oncogene homolog 0.490072
HTN3 histatin 3 0.468063
CLDN11 claudin 11 0.463905
KRT15 keratin 15, type I 0.453339
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 0.452962
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.429266
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase 0.374809
LOX lysyl oxidase 0.364085
ADD1 adducin 1 (alpha) 0.351555
MSX2 msh homeobox 2 0.335412
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.312464
VCAN versican 0.256299
BGN biglycan 0.248905
LIG3 ligase III, DNA, ATP-dependent 0.208914
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.192344
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2) 0.179239
SP1 Sp1 transcription factor 0.164149
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.163729
TYRO3 TYRO3 protein tyrosine kinase 0.161523
C6ORF25 chromosome 6 open reading frame 25 0.158778