| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cotinine-1511 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ALDOB | aldolase B, fructose-bisphosphate |
| ARHGAP26 | Rho GTPase activating protein 26 |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ASIC4 | acid sensing (proton gated) ion channel family member 4 |
| C11ORF21 | chromosome 11 open reading frame 21 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CALB1 | calbindin 1, 28kDa |
| CD79B | CD79b molecule, immunoglobulin-associated beta |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEP152 | centrosomal protein 152kDa |
| CHD5 | chromodomain helicase DNA binding protein 5 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTBS | chitobiase, di-N-acetyl- |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DIO2 | deiodinase, iodothyronine, type II |
| DMRT1 | doublesex and mab-3 related transcription factor 1 |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EPHB2 | EPH receptor B2 |
| ERAP1 | endoplasmic reticulum aminopeptidase 1 |
| EXO5 | exonuclease 5 |
| EXOC6B | exocyst complex component 6B |
| FAM120C | family with sequence similarity 120C |
| FAM76A | family with sequence similarity 76, member A |
| FLJ11710 | uncharacterized protein FLJ11710 |
| GSTP1 | glutathione S-transferase pi 1 |
| HOXC8 | homeobox C8 |
| HRK | harakiri, BCL2 interacting protein |
| IPO9 | importin 9 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| KDM5A | lysine (K)-specific demethylase 5A |
| KLF6 | Kruppel-like factor 6 |
| KLHL22 | kelch-like family member 22 |
| LENEP | lens epithelial protein |
| LOXL2 | lysyl oxidase-like 2 |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MARS | methionyl-tRNA synthetase |
| MFAP3L | microfibrillar-associated protein 3-like |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MPPE1 | metallophosphoesterase 1 |
| MTCP1 | mature T-cell proliferation 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NOL10 | nucleolar protein 10 |
| NOX1 | NADPH oxidase 1 |
| NPAT | nuclear protein, ataxia-telangiectasia locus |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NUP54 | nucleoporin 54kDa |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PCNX | pecanex homolog (Drosophila) |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PRY | PTPN13-like, Y-linked |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RAB40C | RAB40C, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RBPMS | RNA binding protein with multiple splicing |
| RCHY1 | ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RNF122 | ring finger protein 122 |
| SCARB2 | scavenger receptor class B, member 2 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC12A5 | solute carrier family 12 (potassium/chloride transporter), member 5 |
| SOCS6 | suppressor of cytokine signaling 6 |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SORCS3 | sortilin-related VPS10 domain containing receptor 3 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| STAB2 | stabilin 2 |
| STS | steroid sulfatase (microsomal), isozyme S |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| SURF1 | surfeit 1 |
| TACC1 | transforming, acidic coiled-coil containing protein 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TLR2 | toll-like receptor 2 |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFRSF25 | tumor necrosis factor receptor superfamily, member 25 |
| TRD | T cell receptor delta locus |
| TRIM36 | tripartite motif containing 36 |
| TUBA3C | tubulin, alpha 3c |
| TWISTNB | TWIST neighbor |
| USB1 | U6 snRNA biogenesis 1 |
| USP34 | ubiquitin specific peptidase 34 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZNF573 | zinc finger protein 573 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ADM | adrenomedullin |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARMC4 | armadillo repeat containing 4 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| B3GALT4 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 |
| BATF | basic leucine zipper transcription factor, ATF-like |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BCL2L2 | BCL2-like 2 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C8ORF60 | chromosome 8 open reading frame 60 |
| CCDC121 | coiled-coil domain containing 121 |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CDK3 | cyclin-dependent kinase 3 |
| CFD | complement factor D (adipsin) |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CORO7 | coronin 7 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DEAF1 | DEAF1 transcription factor |
| DOC2A | double C2-like domains, alpha |
| DUSP8 | dual specificity phosphatase 8 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| FBXL15 | F-box and leucine-rich repeat protein 15 |
| FKBP5 | FK506 binding protein 5 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GMPR | guanosine monophosphate reductase |
| GRTP1 | growth hormone regulated TBC protein 1 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HHLA3 | HERV-H LTR-associating 3 |
| HIST1H2AI | histone cluster 1, H2ai |
| INCENP | inner centromere protein antigens 135/155kDa |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| ITGA10 | integrin, alpha 10 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LIN7B | lin-7 homolog B (C. elegans) |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| LRP6 | low density lipoprotein receptor-related protein 6 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MCOLN1 | mucolipin 1 |
| MCOLN3 | mucolipin 3 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MMP2 | matrix metallopeptidase 2 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| MYO1E | myosin IE |
| NDE1 | nudE neurodevelopment protein 1 |
| NES | nestin |
| NPFFR1 | neuropeptide FF receptor 1 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR12D2 | olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene) |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PERP | PERP, TP53 apoptosis effector |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLD2 | phospholipase D2 |
| POLH | polymerase (DNA directed), eta |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PROCR | protein C receptor, endothelial |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RAB30 | RAB30, member RAS oncogene family |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB8B | RAB8B, member RAS oncogene family |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RIN2 | Ras and Rab interactor 2 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| SAMHD1 | SAM domain and HD domain 1 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SETD1A | SET domain containing 1A |
| SETD1B | SET domain containing 1B |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| THAP7 | THAP domain containing 7 |
| THBS3 | thrombospondin 3 |
| THNSL2 | threonine synthase-like 2 (S. cerevisiae) |
| TIPRL | TOR signaling pathway regulator |
| ULBP2 | UL16 binding protein 2 |
| VASH1 | vasohibin 1 |
| VAX2 | ventral anterior homeobox 2 |
| VEGFC | vascular endothelial growth factor C |
| VPS11 | vacuolar protein sorting 11 homolog (S. cerevisiae) |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| XAB2 | XPA binding protein 2 |
| ZNF428 | zinc finger protein 428 |
| ZNF552 | zinc finger protein 552 |
