| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cotinine-2011 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ACAN | aggrecan |
| ADAMTS2 | ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| ADGRE1 | adhesion G protein-coupled receptor E1 |
| ADORA1 | adenosine A1 receptor |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| BCL2L1 | BCL2-like 1 |
| BMP1 | bone morphogenetic protein 1 |
| C1ORF95 | chromosome 1 open reading frame 95 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| C6ORF15 | chromosome 6 open reading frame 15 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACYBP | calcyclin binding protein |
| CARTPT | CART prepropeptide |
| CBY1 | chibby homolog 1 (Drosophila) |
| CC2D1A | coiled-coil and C2 domain containing 1A |
| CCL4 | chemokine (C-C motif) ligand 4 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CDS2 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 |
| CLDN15 | claudin 15 |
| COQ4 | coenzyme Q4 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 |
| ELMO2 | engulfment and cell motility 2 |
| ESR2 | estrogen receptor 2 (ER beta) |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FLOT2 | flotillin 2 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GJA9 | gap junction protein, alpha 9, 59kDa |
| HIRA | histone cell cycle regulator |
| HMGA2 | high mobility group AT-hook 2 |
| HTT | huntingtin |
| IDS | iduronate 2-sulfatase |
| IL13RA1 | interleukin 13 receptor, alpha 1 |
| INO80B | INO80 complex subunit B |
| IRF4 | interferon regulatory factor 4 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| ITSN1 | intersectin 1 (SH3 domain protein) |
| ITSN2 | intersectin 2 |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KIFC1 | kinesin family member C1 |
| KYNU | kynureninase |
| LONP2 | lon peptidase 2, peroxisomal |
| LTB4R | leukotriene B4 receptor |
| MAPK10 | mitogen-activated protein kinase 10 |
| MASP1 | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) |
| MED20 | mediator complex subunit 20 |
| MED27 | mediator complex subunit 27 |
| MKS1 | Meckel syndrome, type 1 |
| MSH3 | mutS homolog 3 |
| MVP | major vault protein |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PAPPA2 | pappalysin 2 |
| PFDN4 | prefoldin subunit 4 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 |
| PGC | progastricsin (pepsinogen C) |
| PRMT7 | protein arginine methyltransferase 7 |
| PRR4 | proline rich 4 (lacrimal) |
| PSG3 | pregnancy specific beta-1-glycoprotein 3 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| R3HDM1 | R3H domain containing 1 |
| RAP1GAP | RAP1 GTPase activating protein |
| REC8 | REC8 meiotic recombination protein |
| RSU1 | Ras suppressor protein 1 |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 |
| SMAD3 | SMAD family member 3 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SMO | smoothened, frizzled class receptor |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPIDR | scaffolding protein involved in DNA repair |
| SPTB | spectrin, beta, erythrocytic |
| SSH3 | slingshot protein phosphatase 3 |
| STK17B | serine/threonine kinase 17b |
| STRN | striatin, calmodulin binding protein |
| SUGP1 | SURP and G patch domain containing 1 |
| TBC1D4 | TBC1 domain family, member 4 |
| TGFB3 | transforming growth factor, beta 3 |
| TM2D1 | TM2 domain containing 1 |
| TMEM120B | transmembrane protein 120B |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TOR4A | torsin family 4, member A |
| TRADD | TNFRSF1A-associated via death domain |
| TRAF4 | TNF receptor-associated factor 4 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRIM9 | tripartite motif containing 9 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBD1 | tubulin, delta 1 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF444 | zinc finger protein 444 |
| ZNF770 | zinc finger protein 770 |
| ZNHIT2 | zinc finger, HIT-type containing 2 |
| Symbol | Name |
|---|---|
| ACP6 | acid phosphatase 6, lysophosphatidic |
| AES | amino-terminal enhancer of split |
| ANAPC10 | anaphase promoting complex subunit 10 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARG1 | arginase 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ASCC1 | activating signal cointegrator 1 complex subunit 1 |
| AURKAIP1 | aurora kinase A interacting protein 1 |
| BBS1 | Bardet-Biedl syndrome 1 |
| BFAR | bifunctional apoptosis regulator |
| C12ORF29 | chromosome 12 open reading frame 29 |
| CAPN1 | calpain 1, (mu/I) large subunit |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CD300C | CD300c molecule |
| CHMP1A | charged multivesicular body protein 1A |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CNTD2 | cyclin N-terminal domain containing 2 |
| CPNE1 | copine I |
| CPOX | coproporphyrinogen oxidase |
| CST3 | cystatin C |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DYM | dymeclin |
| EMC6 | ER membrane protein complex subunit 6 |
| FASTKD5 | FAST kinase domains 5 |
| FMO4 | flavin containing monooxygenase 4 |
| GAB2 | GRB2-associated binding protein 2 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
| GMPPB | GDP-mannose pyrophosphorylase B |
| GNA12 | guanine nucleotide binding protein (G protein) alpha 12 |
| GPATCH3 | G patch domain containing 3 |
| GPR21 | G protein-coupled receptor 21 |
| GRPR | gastrin-releasing peptide receptor |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HERC1 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| INO80D | INO80 complex subunit D |
| JMJD4 | jumonji domain containing 4 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KPTN | kaptin (actin binding protein) |
| KRT38 | keratin 38, type I |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| LRRC37A2 | leucine rich repeat containing 37, member A2 |
| MANBA | mannosidase, beta A, lysosomal |
| MLPH | melanophilin |
| MMP2 | matrix metallopeptidase 2 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 |
| MT1HL1 | metallothionein 1H-like 1 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NOL6 | nucleolar protein 6 (RNA-associated) |
| OPHN1 | oligophrenin 1 |
| OSTF1 | osteoclast stimulating factor 1 |
| PCDHGB5 | protocadherin gamma subfamily B, 5 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIGL | phosphatidylinositol glycan anchor biosynthesis, class L |
| PLCD1 | phospholipase C, delta 1 |
| POR | P450 (cytochrome) oxidoreductase |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PTPN9 | protein tyrosine phosphatase, non-receptor type 9 |
| RAD9A | RAD9 homolog A (S. pombe) |
| RARS | arginyl-tRNA synthetase |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RHOH | ras homolog family member H |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SIRT1 | sirtuin 1 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SPX | spexin hormone |
| STAG1 | stromal antigen 1 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TBL3 | transducin (beta)-like 3 |
| TEX40 | testis expressed 40 |
| TGIF1 | TGFB-induced factor homeobox 1 |
| THAP1 | THAP domain containing, apoptosis associated protein 1 |
| TM7SF3 | transmembrane 7 superfamily member 3 |
| TMEM115 | transmembrane protein 115 |
| TMEM127 | transmembrane protein 127 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TPX2 | TPX2, microtubule-associated |
| TSR2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) |
| TUBA3D | tubulin, alpha 3d |
| UFM1 | ubiquitin-fold modifier 1 |
| UNKL | unkempt family zinc finger-like |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| WDR18 | WD repeat domain 18 |
| XDH | xanthine dehydrogenase |
| ZNF804A | zinc finger protein 804A |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
| ZW10 | zw10 kinetochore protein |
