| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the cotinine-4650 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTN2 | actinin, alpha 2 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| APOC4 | apolipoprotein C-IV |
| ARHGAP25 | Rho GTPase activating protein 25 |
| B3GALT2 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 |
| BMP8A | bone morphogenetic protein 8a |
| BTG2 | BTG family, member 2 |
| BTNL8 | butyrophilin-like 8 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C8A | complement component 8, alpha polypeptide |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CABP1 | calcium binding protein 1 |
| CAMK1G | calcium/calmodulin-dependent protein kinase IG |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CCL11 | chemokine (C-C motif) ligand 11 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCR2 | chemokine (C-C motif) receptor 2 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CHRNE | cholinergic receptor, nicotinic, epsilon (muscle) |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| COL16A1 | collagen, type XVI, alpha 1 |
| CORT | cortistatin |
| CRP | C-reactive protein, pentraxin-related |
| CSHL1 | chorionic somatomammotropin hormone-like 1 |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| EGR1 | early growth response 1 |
| EML3 | echinoderm microtubule associated protein like 3 |
| EPHA3 | EPH receptor A3 |
| FPR1 | formyl peptide receptor 1 |
| FRMD4B | FERM domain containing 4B |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| FYB | FYN binding protein |
| GRIK3 | glutamate receptor, ionotropic, kainate 3 |
| GSN-AS1 | GSN antisense RNA 1 |
| HEATR6 | HEAT repeat containing 6 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha |
| HSPG2 | heparan sulfate proteoglycan 2 |
| HTR7P1 | 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1 |
| ING2 | inhibitor of growth family, member 2 |
| IRF5 | interferon regulatory factor 5 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) |
| KALRN | kalirin, RhoGEF kinase |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KCNH1 | potassium channel, voltage gated eag related subfamily H, member 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| KLHL35 | kelch-like family member 35 |
| LST1 | leukocyte specific transcript 1 |
| LTA | lymphotoxin alpha |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| LY9 | lymphocyte antigen 9 |
| MAN1C1 | mannosidase, alpha, class 1C, member 1 |
| MR1 | major histocompatibility complex, class I-related |
| MS4A2 | membrane-spanning 4-domains, subfamily A, member 2 |
| MYT1L | myelin transcription factor 1-like |
| NDOR1 | NADPH dependent diflavin oxidoreductase 1 |
| NPR1 | natriuretic peptide receptor 1 |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NUDC | nudC nuclear distribution protein |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 |
| ORC5 | origin recognition complex, subunit 5 |
| OTOF | otoferlin |
| PCDH1 | protocadherin 1 |
| PCDH11Y | protocadherin 11 Y-linked |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 |
| POU3F2 | POU class 3 homeobox 2 |
| PRDM12 | PR domain containing 12 |
| PTCH2 | patched 2 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| RFXAP | regulatory factor X-associated protein |
| RGS12 | regulator of G-protein signaling 12 |
| RRH | retinal pigment epithelium-derived rhodopsin homolog |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SCN2B | sodium channel, voltage gated, type II beta subunit |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERHL2 | serine hydrolase-like 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SIGLEC8 | sialic acid binding Ig-like lectin 8 |
| SLC3A1 | solute carrier family 3 (amino acid transporter heavy chain), member 1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC5A12 | solute carrier family 5 (sodium/monocarboxylate cotransporter), member 12 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SPATA6 | spermatogenesis associated 6 |
| STX7 | syntaxin 7 |
| SUGP1 | SURP and G patch domain containing 1 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAOK1 | TAO kinase 1 |
| TLN2 | talin 2 |
| TMEM246 | transmembrane protein 246 |
| TMPRSS4 | transmembrane protease, serine 4 |
| TP63 | tumor protein p63 |
| TPM2 | tropomyosin 2 (beta) |
| TRGV5 | T cell receptor gamma variable 5 |
| USP2 | ubiquitin specific peptidase 2 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ABHD17B | abhydrolase domain containing 17B |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ANXA2P1 | annexin A2 pseudogene 1 |
| ARL14 | ADP-ribosylation factor-like 14 |
| ARMC6 | armadillo repeat containing 6 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| BAG4 | BCL2-associated athanogene 4 |
| BAX | BCL2-associated X protein |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C4ORF19 | chromosome 4 open reading frame 19 |
| CA9 | carbonic anhydrase IX |
| CCDC85C | coiled-coil domain containing 85C |
| CEP131 | centrosomal protein 131kDa |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CHM | choroideremia (Rab escort protein 1) |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DDB1 | damage-specific DNA binding protein 1, 127kDa |
| DENND2D | DENN/MADD domain containing 2D |
| DENND4A | DENN/MADD domain containing 4A |
| EFNA3 | ephrin-A3 |
| ELP3 | elongator acetyltransferase complex subunit 3 |
| EML4 | echinoderm microtubule associated protein like 4 |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| ERF | Ets2 repressor factor |
| FAM131A | family with sequence similarity 131, member A |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FPGS | folylpolyglutamate synthase |
| FUZ | fuzzy planar cell polarity protein |
| GABPA | GA binding protein transcription factor, alpha subunit 60kDa |
| GALT | galactose-1-phosphate uridylyltransferase |
| GID4 | GID complex subunit 4 |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPATCH2L | G patch domain containing 2-like |
| GTF2H2B | general transcription factor IIH, polypeptide 2B (pseudogene) |
| HELZ | helicase with zinc finger |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 |
| HMOX1 | heme oxygenase 1 |
| IFT54 | intraflagellar transport 54 |
| INCENP | inner centromere protein antigens 135/155kDa |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIMS2 | LIM and senescent cell antigen-like domains 2 |
| LMAN1 | lectin, mannose-binding, 1 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MX1 | MX dynamin-like GTPase 1 |
| NDP | Norrie disease (pseudoglioma) |
| NME5 | NME/NM23 family member 5 |
| NPFFR1 | neuropeptide FF receptor 1 |
| OSMR | oncostatin M receptor |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PAK6 | p21 protein (Cdc42/Rac)-activated kinase 6 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PFDN6 | prefoldin subunit 6 |
| PLA2G4A | phospholipase A2, group IVA (cytosolic, calcium-dependent) |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLSCR4 | phospholipid scramblase 4 |
| PRR4 | proline rich 4 (lacrimal) |
| PRSS53 | protease, serine, 53 |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| ROM1 | retinal outer segment membrane protein 1 |
| RPH3AL | rabphilin 3A-like (without C2 domains) |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SH3TC2 | SH3 domain and tetratricopeptide repeats 2 |
| SIRAL2 | SIR2 antiphage like 2 |
| SLC22A18 | solute carrier family 22, member 18 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SSBP3 | single stranded DNA binding protein 3 |
| TEX40 | testis expressed 40 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM121 | transmembrane protein 121 |
| TMEM156 | transmembrane protein 156 |
| TOR4A | torsin family 4, member A |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM16 | tripartite motif containing 16 |
| TWISTNB | TWIST neighbor |
| ULBP2 | UL16 binding protein 2 |
| WDR76 | WD repeat domain 76 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFP30 | ZFP30 zinc finger protein |
| ZNF141 | zinc finger protein 141 |
| ZNF165 | zinc finger protein 165 |
| ZNF510 | zinc finger protein 510 |
| ZNF747 | zinc finger protein 747 |
| ZNF76 | zinc finger protein 76 |
| ZNF787 | zinc finger protein 787 |
