| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the cotinine-5246 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AIRE | autoimmune regulator |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| AQP3 | aquaporin 3 (Gill blood group) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATN1 | atrophin 1 |
| ATP11A | ATPase, class VI, type 11A |
| C19ORF66 | chromosome 19 open reading frame 66 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CD52 | CD52 molecule |
| CD53 | CD53 molecule |
| CD93 | CD93 molecule |
| CDC42 | cell division cycle 42 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) |
| CDON | cell adhesion associated, oncogene regulated |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLEC10A | C-type lectin domain family 10, member A |
| COL19A1 | collagen, type XIX, alpha 1 |
| COL6A1 | collagen, type VI, alpha 1 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNAH7 | dynein, axonemal, heavy chain 7 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| EPHB6 | EPH receptor B6 |
| EPX | eosinophil peroxidase |
| FAM76A | family with sequence similarity 76, member A |
| FZD9 | frizzled class receptor 9 |
| GAST | gastrin |
| GHRHR | growth hormone releasing hormone receptor |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GM2A | GM2 ganglioside activator |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| IFNA17 | interferon, alpha 17 |
| IFNA2 | interferon, alpha 2 |
| IGL | immunoglobulin lambda locus |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| KANSL3 | KAT8 regulatory NSL complex subunit 3 |
| KIAA0195 | KIAA0195 |
| KRT19P2 | keratin 19 pseudogene 2 |
| KRT31 | keratin 31, type I |
| KRT38 | keratin 38, type I |
| KRT6B | keratin 6B, type II |
| KSR1 | kinase suppressor of ras 1 |
| LILRA4 | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LPPR1 | lipid phosphate phosphatase-related protein type 1 |
| LUZP4 | leucine zipper protein 4 |
| MAN1A2 | mannosidase, alpha, class 1A, member 2 |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MTMR7 | myotubularin related protein 7 |
| OLFML2A | olfactomedin-like 2A |
| ORAI2 | ORAI calcium release-activated calcium modulator 2 |
| PADI3 | peptidyl arginine deiminase, type III |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 |
| PDE1B | phosphodiesterase 1B, calmodulin-dependent |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PIP | prolactin-induced protein |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLXNC1 | plexin C1 |
| PML | promyelocytic leukemia |
| PON3 | paraoxonase 3 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PSAT1 | phosphoserine aminotransferase 1 |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| REEP2 | receptor accessory protein 2 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SALL1 | spalt-like transcription factor 1 |
| SCN4A | sodium channel, voltage gated, type IV alpha subunit |
| SERPINA7 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 |
| SIX3 | SIX homeobox 3 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SULT2A1 | sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 |
| TAAR5 | trace amine associated receptor 5 |
| TBC1D1 | TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 |
| TECPR2 | tectonin beta-propeller repeat containing 2 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TGFA | transforming growth factor, alpha |
| THRB | thyroid hormone receptor, beta |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TONSL | tonsoku-like, DNA repair protein |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRH | thyrotropin-releasing hormone |
| TRIM29 | tripartite motif containing 29 |
| TSC2 | tuberous sclerosis 2 |
| UPK3B | uroplakin 3B |
| VN1R1 | vomeronasal 1 receptor 1 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF415 | zinc finger protein 415 |
| ZNF518A | zinc finger protein 518A |
| Symbol | Name |
|---|---|
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ABHD17B | abhydrolase domain containing 17B |
| ADAM15 | ADAM metallopeptidase domain 15 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| AMT | aminomethyltransferase |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARMC4 | armadillo repeat containing 4 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCNO | cyclin O |
| CES3 | carboxylesterase 3 |
| CHKB | choline kinase beta |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLGN | calmegin |
| CUL9 | cullin 9 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYB5R1 | cytochrome b5 reductase 1 |
| DEPDC1 | DEP domain containing 1 |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FFAR2 | free fatty acid receptor 2 |
| GAMT | guanidinoacetate N-methyltransferase |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HGS | hepatocyte growth factor-regulated tyrosine kinase substrate |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| HYI | hydroxypyruvate isomerase (putative) |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGFBP6 | insulin-like growth factor binding protein 6 |
| KLF3 | Kruppel-like factor 3 (basic) |
| KLHL28 | kelch-like family member 28 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) |
| MANBA | mannosidase, beta A, lysosomal |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NKRF | NFKB repressing factor |
| NLRX1 | NLR family member X1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NXPH4 | neurexophilin 4 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PCDHA5 | protocadherin alpha 5 |
| PNPO | pyridoxamine 5'-phosphate oxidase |
| PRSS53 | protease, serine, 53 |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RAI2 | retinoic acid induced 2 |
| RARS | arginyl-tRNA synthetase |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| RBM42 | RNA binding motif protein 42 |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGS2 | regulator of G-protein signaling 2 |
| RHOC | ras homolog family member C |
| RNF123 | ring finger protein 123 |
| RNF39 | ring finger protein 39 |
| RNPEPL1 | arginyl aminopeptidase (aminopeptidase B)-like 1 |
| RUNDC3B | RUN domain containing 3B |
| SEC61A2 | Sec61 alpha 2 subunit (S. cerevisiae) |
| SH2D4A | SH2 domain containing 4A |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIX1 | SIX homeobox 1 |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 |
| SP1 | Sp1 transcription factor |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TLR5 | toll-like receptor 5 |
| TMEM2 | transmembrane protein 2 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TRIM36 | tripartite motif containing 36 |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBE2NL | ubiquitin-conjugating enzyme E2N-like (gene/pseudogene) |
| UBXN6 | UBX domain protein 6 |
| VEZT | vezatin, adherens junctions transmembrane protein |
| VGF | VGF nerve growth factor inducible |
| VPS9D1 | VPS9 domain containing 1 |
| WDR18 | WD repeat domain 18 |
| XYLT2 | xylosyltransferase II |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZFHX4 | zinc finger homeobox 4 |
| ZIC3 | Zic family member 3 |
| ZNF10 | zinc finger protein 10 |
| ZNF34 | zinc finger protein 34 |
| ZNF552 | zinc finger protein 552 |
| ZNF668 | zinc finger protein 668 |
