coupling Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

380 genes co-occuring with the biological term coupling in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABI1 abl-interactor 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACKR3 atypical chemokine receptor 3
ADIPOQ adiponectin, C1Q and collagen domain containing
ADORA1 adenosine A1 receptor
ADORA2A adenosine A2a receptor
ADORA2B adenosine A2b receptor
ADRA1B adrenoceptor alpha 1B
ADRB1 adrenoceptor beta 1
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
AGR2 anterior gradient 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
ALOX5 arachidonate 5-lipoxygenase
ANO1 anoctamin 1, calcium activated chloride channel
APLN apelin
APLNR apelin receptor
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARHGAP8 Rho GTPase activating protein 8
ARHGEF5 Rho guanine nucleotide exchange factor (GEF) 5
ARRB2 arrestin, beta 2
ATG101 autophagy related 101
ATG7 autophagy related 7
ATM ATM serine/threonine kinase
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP5J ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6
ATP7B ATPase, Cu++ transporting, beta polypeptide
BCAR1 breast cancer anti-estrogen resistance 1
BDKRB1 bradykinin receptor B1
BDKRB2 bradykinin receptor B2
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRIP1 BRCA1 interacting protein C-terminal helicase 1
C5AR2 complement component 5a receptor 2
CABIN1 calcineurin binding protein 1
CABP1 calcium binding protein 1
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1S calcium channel, voltage-dependent, L type, alpha 1S subunit
CALCA calcitonin-related polypeptide alpha
CALCRL calcitonin receptor-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP7 caspase 7, apoptosis-related cysteine peptidase
CCNE1 cyclin E1
CD163 CD163 molecule
CD28 CD28 molecule
CD300LB CD300 molecule-like family member b
CD34 CD34 molecule
CD47 CD47 molecule
CD82 CD82 molecule
CDC25A cell division cycle 25A
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDK6 cyclin-dependent kinase 6
CDK9 cyclin-dependent kinase 9
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK1 checkpoint kinase 1
CHERP calcium homeostasis endoplasmic reticulum protein
CHMP3 charged multivesicular body protein 3
CHRM1 cholinergic receptor, muscarinic 1
CHRM2 cholinergic receptor, muscarinic 2
CHRM3 cholinergic receptor, muscarinic 3
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CKMT2 creatine kinase, mitochondrial 2 (sarcomeric)
CLU clusterin
CNR1 cannabinoid receptor 1 (brain)
CNR2 cannabinoid receptor 2 (macrophage)
CPLX1 complexin 1
CRHR1 corticotropin releasing hormone receptor 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR4 chemokine (C-X-C motif) receptor 4
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DBN1 drebrin 1
DCAF7 DDB1 and CUL4 associated factor 7
DISC1 disrupted in schizophrenia 1
DLG1 discs, large homolog 1 (Drosophila)
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DYSF dysferlin
EDNRA endothelin receptor type A
EGFR epidermal growth factor receptor
EHBP1 EH domain binding protein 1
ENG endoglin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB4 erb-b2 receptor tyrosine kinase 4
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F11 coagulation factor XI
F2RL1 coagulation factor II (thrombin) receptor-like 1
FASTKD3 FAST kinase domains 3
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32)
FES FES proto-oncogene, tyrosine kinase
FFAR1 free fatty acid receptor 1
FFAR2 free fatty acid receptor 2
FFAR3 free fatty acid receptor 3
FHL2 four and a half LIM domains 2
FKBP1A FK506 binding protein 1A, 12kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOXO1 forkhead box O1
FOXO3 forkhead box O3
FSHR follicle stimulating hormone receptor
FURIN furin (paired basic amino acid cleaving enzyme)
GAB1 GRB2-associated binding protein 1
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRR1 gamma-aminobutyric acid (GABA) A receptor, rho 1
GCGR glucagon receptor
GCH1 GTP cyclohydrolase 1
GHR growth hormone receptor
GJA1 gap junction protein, alpha 1, 43kDa
GJA3 gap junction protein, alpha 3, 46kDa
GJA5 gap junction protein, alpha 5, 40kDa
GJB2 gap junction protein, beta 2, 26kDa
GJC2 gap junction protein, gamma 2, 47kDa
GJD2 gap junction protein, delta 2, 36kDa
GLI1 GLI family zinc finger 1
GLS glutaminase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNAS GNAS complex locus
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRHR gonadotropin-releasing hormone receptor
GORASP2 golgi reassembly stacking protein 2, 55kDa
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPBAR1 G protein-coupled bile acid receptor 1
GPER1 G protein-coupled estrogen receptor 1
GPR35 G protein-coupled receptor 35
GPR65 G protein-coupled receptor 65
GPSM1 G-protein signaling modulator 1
GRB2 growth factor receptor-bound protein 2
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GRM1 glutamate receptor, metabotropic 1
GRM6 glutamate receptor, metabotropic 6
HBA1 hemoglobin, alpha 1
HBB hemoglobin, beta
HCK HCK proto-oncogene, Src family tyrosine kinase
HCRTR1 hypocretin (orexin) receptor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIF1AN hypoxia inducible factor 1, alpha subunit inhibitor
HIPK2 homeodomain interacting protein kinase 2
HIST2H4A histone cluster 2, H4a
HNRNPK heterogeneous nuclear ribonucleoprotein K
HP haptoglobin
HRH1 histamine receptor H1
HRH3 histamine receptor H3
HSD17B3 hydroxysteroid (17-beta) dehydrogenase 3
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL2 interleukin 2
IL2RA interleukin 2 receptor, alpha
IL6 interleukin 6
INS insulin
IQGAP1 IQ motif containing GTPase activating protein 1
IRS1 insulin receptor substrate 1
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JPH1 junctophilin 1
JPH2 junctophilin 2
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNIP3 Kv channel interacting protein 3, calsenilin
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11
KCNJ6 potassium channel, inwardly rectifying subfamily J, member 6
KCNK3 potassium channel, two pore domain subfamily K, member 3
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4
KCNT2 potassium channel, sodium activated subfamily T, member 2
KDR kinase insert domain receptor
KIAA0368 KIAA0368
KSR1 kinase suppressor of ras 1
LIMS1 LIM and senescent cell antigen-like domains 1
LTB4R leukotriene B4 receptor
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MC4R melanocortin 4 receptor
MCHR2 melanin-concentrating hormone receptor 2
MCL1 myeloid cell leukemia 1
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP9 matrix metallopeptidase 9
MPO myeloperoxidase
MRAP melanocortin 2 receptor accessory protein
MRAS muscle RAS oncogene homolog
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MYB v-myb avian myeloblastosis viral oncogene homolog
MYBPC2 myosin binding protein C, fast type
MYD88 myeloid differentiation primary response 88
MYOCD myocardin
NAMPT nicotinamide phosphoribosyltransferase
NBN nibrin
NCF4 neutrophil cytosolic factor 4, 40kDa
NELFB negative elongation factor complex member B
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (human; man).
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKRF NFKB repressing factor
NOS1 nitric oxide synthase 1 (neuronal)
NOS3 nitric oxide synthase 3 (endothelial cell)
NOX1 NADPH oxidase 1
NPR3 natriuretic peptide receptor 3
NPSR1 neuropeptide S receptor 1
NR3C2 nuclear receptor subfamily 3, group C, member 2
NRG2 neuregulin 2
OPRD1 opioid receptor, delta 1
OPRM1 opioid receptor, mu 1
ORAI1 ORAI calcium release-activated calcium modulator 1
OSM oncostatin M
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY1 purinergic receptor P2Y, G-protein coupled, 1
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PAH phenylalanine hydroxylase
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PEA15 phosphoprotein enriched in astrocytes 15
PECAM1 platelet/endothelial cell adhesion molecule 1
PELP1 proline, glutamate and leucine rich protein 1
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PKLR pyruvate kinase, liver and RBC
PLA2G1B phospholipase A2, group IB (pancreas)
PLD2 phospholipase D2
PLEKHA8 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
PLXNB1 plexin B1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PML promyelocytic leukemia
PNKD paroxysmal nonkinesigenic dyskinesia
PPARD peroxisome proliferator-activated receptor delta
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKCA protein kinase C, alpha
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKD1 protein kinase D1
PROKR2 prokineticin receptor 2
PTAFR platelet-activating factor receptor
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTGIR prostaglandin I2 (prostacyclin) receptor (IP)
PTHLH parathyroid hormone-like hormone
PTPN3 protein tyrosine phosphatase, non-receptor type 3
QDPR quinoid dihydropteridine reductase
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB4A RAB4A, member RAS oncogene family
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD18 RAD18 E3 ubiquitin protein ligase
RAMP2 receptor (G protein-coupled) activity modifying protein 2
RANBP9 RAN binding protein 9
RB1 retinoblastoma 1
RBBP8 retinoblastoma binding protein 8
RBM5 RNA binding motif protein 5
RET ret proto-oncogene
RGS4 regulator of G-protein signaling 4
RHOA ras homolog family member A
RIMS1 regulating synaptic membrane exocytosis 1
RIT1 Ras-like without CAAX 1
RUNX2 runt-related transcription factor 2
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
S1PR3 sphingosine-1-phosphate receptor 3
SCN5A sodium channel, voltage gated, type V alpha subunit
SCN9A sodium channel, voltage gated, type IX alpha subunit
SCRIB scribbled planar cell polarity protein
SEC13 SEC13 homolog (S. cerevisiae)
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24B SEC24 family member B
SEC31A SEC31 homolog A (S. cerevisiae)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3GL1 SH3-domain GRB2-like 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHH sonic hedgehog
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
SLC25A4 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC26A5 solute carrier family 26 (anion exchanger), member 5
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SLC28A2 solute carrier family 28 (concentrative nucleoside transporter), member 2
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SMO smoothened, frizzled class receptor
SNX9 sorting nexin 9
SOS1 son of sevenless homolog 1 (Drosophila)
SPAST spastin
SPRY2 sprouty homolog 2 (Drosophila)
SPTB spectrin, beta, erythrocytic
SSRP1 structure specific recognition protein 1
SSTR4 somatostatin receptor 4
STAMBP STAM binding protein
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIM1 stromal interaction molecule 1
STIM2 stromal interaction molecule 2
SYT1 synaptotagmin I
SYT2 synaptotagmin II
TBX18 T-box 18
TBXA2R thromboxane A2 receptor
TCERG1 transcription elongation regulator 1
TEK TEK tyrosine kinase, endothelial
TET1 tet methylcytosine dioxygenase 1
THBD thrombomodulin
TICAM2 toll-like receptor adaptor molecule 2
TIPIN TIMELESS interacting protein
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLX2 T-cell leukemia homeobox 2
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNNI3 troponin I type 3 (cardiac)
TP53 tumor protein p53
TRAM2 translocation associated membrane protein 2
TRIP6 thyroid hormone receptor interactor 6
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM1 transient receptor potential cation channel, subfamily M, member 1
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSC1 tuberous sclerosis 1
TSHR thyroid stimulating hormone receptor
TSTA3 tissue specific transplantation antigen P35B
TWIST2 twist family bHLH transcription factor 2
UBE2A ubiquitin-conjugating enzyme E2A
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase
ULK1 unc-51 like autophagy activating kinase 1
VAC14 Vac14 homolog (S. cerevisiae)
VAV2 vav 2 guanine nucleotide exchange factor
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VIPR1 vasoactive intestinal peptide receptor 1
VIPR2 vasoactive intestinal peptide receptor 2
WASF2 WAS protein family, member 2
XRN1 5'-3' exoribonuclease 1
XRN2 5'-3' exoribonuclease 2
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZNF804A zinc finger protein 804A