crenolanib Gene Set
Genes
16 genes differentially expressed following the crenolanib small molecule perturbation from the LINCS L1000 CMAP Chemical Perturbation Consensus Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PDGFRL
|
platelet-derived growth factor receptor-like
|
3.79095
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.5809
|
|
ANKEF1
|
ankyrin repeat and EF-hand domain containing 1
|
3.10863
|
|
GPR143
|
G protein-coupled receptor 143
|
3.04767
|
|
STEAP1
|
six transmembrane epithelial antigen of the prostate 1
|
3.02255
|
|
DES
|
desmin
|
3.0181
|
|
INTS7
|
integrator complex subunit 7
|
3.00929
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NFATC3
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
|
-3.67932
|
|
KANSL1L
|
KAT8 regulatory NSL complex subunit 1-like
|
-3.51776
|
|
SLC2A5
|
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
|
-3.3857
|
|
CD40
|
CD40 molecule, TNF receptor superfamily member 5
|
-3.27563
|
|
MOBP
|
myelin-associated oligodendrocyte basic protein
|
-3.20448
|
|
LRP1B
|
low density lipoprotein receptor-related protein 1B
|
-3.15441
|
|
SLC37A4
|
solute carrier family 37 (glucose-6-phosphate transporter), member 4
|
-3.12211
|
|
PLEKHB1
|
pleckstrin homology domain containing, family B (evectins) member 1
|
-3.11994
|
|
TNFSF12
|
tumor necrosis factor (ligand) superfamily, member 12
|
-3.07787
|
