| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | crizotinib perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the crizotinib_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.191475 |
| LPIN1 | lipin 1 | 0.119618 |
| HELZ | helicase with zinc finger | 0.103881 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0803621 |
| FAM13A | family with sequence similarity 13, member A | 0.065469 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0635073 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0611931 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0601971 |
| FMN1 | formin 1 | 0.0599519 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0590774 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0561269 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0560011 |
| MED13 | mediator complex subunit 13 | 0.0556412 |
| MED13L | mediator complex subunit 13-like | 0.0551059 |
| MSI2 | musashi RNA-binding protein 2 | 0.0506246 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0505923 |
| SEPTIN9 | septin 9 | 0.0503198 |
| PTK2 | protein tyrosine kinase 2 | 0.0502205 |
| MYO6 | myosin VI | 0.0486096 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0476684 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0476431 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.047032 |
| PPM1D | protein phosphatase, Mg2+/Mn2+ dependent, 1D | 0.046715 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0463053 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0455733 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0426832 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0426243 |
| ZNF148 | zinc finger protein 148 | 0.0426075 |
| CDC73 | cell division cycle 73 | 0.0423023 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0419619 |
| ZNF292 | zinc finger protein 292 | 0.0416588 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0415253 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0413958 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.040988 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.040593 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.040446 |
| NCKAP1 | NCK-associated protein 1 | 0.0401747 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0400457 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0398047 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0393684 |
| TLK2 | tousled-like kinase 2 | 0.0388154 |
| TRIB2 | tribbles pseudokinase 2 | 0.0387827 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0375734 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0372327 |
| PCM1 | pericentriolar material 1 | 0.0371639 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0370905 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0369105 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0363027 |
| HNRNPM | heterogeneous nuclear ribonucleoprotein M | 0.0355911 |
| WDR43 | WD repeat domain 43 | 0.0355124 |
| RYBP | RING1 and YY1 binding protein | 0.0354586 |
| QKI | QKI, KH domain containing, RNA binding | 0.0353162 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0351213 |
| TCF12 | transcription factor 12 | 0.0350971 |
| USP3 | ubiquitin specific peptidase 3 | 0.0342657 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0337321 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0336766 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0336009 |
| DTNA | dystrobrevin, alpha | 0.033254 |
| SETD2 | SET domain containing 2 | 0.0331704 |
| DNMBP | dynamin binding protein | 0.0326286 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0320032 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0319934 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0318152 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0316283 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0315201 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0311374 |
| PDE8A | phosphodiesterase 8A | 0.0303782 |
| CCNL1 | cyclin L1 | 0.0301014 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0300636 |
| XPO1 | exportin 1 | 0.0300456 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0298593 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0297119 |
| MATR3 | matrin 3 | 0.0295851 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0295116 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0292579 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0292105 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0291948 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0291123 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0290955 |
| YTHDC1 | YTH domain containing 1 | 0.0286938 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0286899 |
| ENAH | enabled homolog (Drosophila) | 0.0284323 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0283038 |
| SCAF4 | SR-related CTD-associated factor 4 | 0.0280825 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0279371 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0279118 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0279002 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0278603 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.027152 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0271518 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0270786 |
| TLE4 | transducin-like enhancer of split 4 | 0.0269854 |
| CCNY | cyclin Y | 0.0268786 |
| CUL3 | cullin 3 | 0.0267987 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0267799 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0266709 |
| RLF | rearranged L-myc fusion | 0.0266398 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0266302 |
| POTEF | POTE ankyrin domain family, member F | 0.0266027 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.321818 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145806 |
| NRG1 | neuregulin 1 | -0.121898 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.120855 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110407 |
| PTMA | prothymosin, alpha | -0.0813425 |
| LSAMP | limbic system-associated membrane protein | -0.0800893 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0729638 |
| NREP | neuronal regeneration related protein | -0.0724815 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0686552 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0669237 |
| VIM | vimentin | -0.0664297 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0657883 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0656613 |
| PLAT | plasminogen activator, tissue | -0.0648925 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0645014 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0625287 |
| GPC5 | glypican 5 | -0.0594164 |
| EXT1 | exostosin glycosyltransferase 1 | -0.05782 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0577464 |
| RNF213 | ring finger protein 213 | -0.0556687 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.055139 |
| SYT1 | synaptotagmin I | -0.0522233 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0519097 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0441846 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0437865 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0421894 |
| PCDH9 | protocadherin 9 | -0.0416827 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0414106 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0410318 |
| FRMD4A | FERM domain containing 4A | -0.0406746 |
| RPL23 | ribosomal protein L23 | -0.0387358 |
| TMSB10 | thymosin beta 10 | -0.0381851 |
| STC1 | stanniocalcin 1 | -0.0381476 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0380967 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0378682 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0374454 |
| RPS6 | ribosomal protein S6 | -0.0370806 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0370426 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0369913 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0357169 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0345674 |
| GDF15 | growth differentiation factor 15 | -0.0342875 |
| COL1A1 | collagen, type I, alpha 1 | -0.0342432 |
| GREM2 | gremlin 2, DAN family BMP antagonist | -0.0342326 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.034156 |
| RPS24 | ribosomal protein S24 | -0.0341026 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0340487 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0339041 |
| RPL12 | ribosomal protein L12 | -0.0335196 |
| RPS3 | ribosomal protein S3 | -0.0329941 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0329369 |
| BPTF | bromodomain PHD finger transcription factor | -0.0327937 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0323197 |
| RPL19 | ribosomal protein L19 | -0.0323077 |
| AEBP2 | AE binding protein 2 | -0.032195 |
| PLPP1 | phospholipid phosphatase 1 | -0.0311401 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0310594 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0302761 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0295972 |
| RPLP1 | ribosomal protein, large, P1 | -0.0295617 |
| ITGA1 | integrin, alpha 1 | -0.0294193 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0289332 |
| FTL | ferritin, light polypeptide | -0.0286589 |
| SLFN5 | schlafen family member 5 | -0.027628 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0275687 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0273826 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0270687 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0262632 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0262374 |
| RAI14 | retinoic acid induced 14 | -0.0260469 |
| B2M | beta-2-microglobulin | -0.0259317 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0256555 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0253276 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0253249 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.024943 |
| RPS27 | ribosomal protein S27 | -0.0243708 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.024292 |
| RPS5 | ribosomal protein S5 | -0.0241405 |
| FHIT | fragile histidine triad | -0.0241347 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0241184 |
| S100A6 | S100 calcium binding protein A6 | -0.0239029 |
| CALD1 | caldesmon 1 | -0.0234373 |
| PCBP3 | poly(rC) binding protein 3 | -0.0232849 |
| ENO1 | enolase 1, (alpha) | -0.0232251 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0232085 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.0231703 |
| CADM2 | cell adhesion molecule 2 | -0.0230972 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0230079 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0229824 |
| HM13 | histocompatibility (minor) 13 | -0.0228715 |
| RBMX | RNA binding motif protein, X-linked | -0.0225619 |
| CENPF | centromere protein F, 350/400kDa | -0.022442 |
| TRMT11 | tRNA methyltransferase 11 homolog (S. cerevisiae) | -0.0222803 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0220636 |
| TMF1 | TATA element modulatory factor 1 | -0.0220477 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0220386 |
| MBTD1 | mbt domain containing 1 | -0.021904 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0218945 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0218328 |
