| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | crizotinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the crizotinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BTBD9 | BTB (POZ) domain containing 9 | 0.15874 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.127385 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0925375 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0796291 |
| PHF3 | PHD finger protein 3 | 0.0711896 |
| LMO7 | LIM domain 7 | 0.0649496 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0634199 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0573272 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0541015 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0518957 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0484718 |
| KIF16B | kinesin family member 16B | 0.0448676 |
| ZNF292 | zinc finger protein 292 | 0.043697 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0428215 |
| VMP1 | vacuole membrane protein 1 | 0.0422094 |
| RBM39 | RNA binding motif protein 39 | 0.0418792 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0409064 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0404859 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.040383 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0397159 |
| SMAD3 | SMAD family member 3 | 0.0387517 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0382053 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0377206 |
| SBF2 | SET binding factor 2 | 0.0367356 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0361833 |
| GOLGB1 | golgin B1 | 0.0361194 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0360302 |
| FNIP2 | folliculin interacting protein 2 | 0.0357061 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0351457 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0349211 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0343506 |
| MLPH | melanophilin | 0.0335496 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0319665 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0317178 |
| STK24 | serine/threonine kinase 24 | 0.0314668 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0307759 |
| MED13L | mediator complex subunit 13-like | 0.0306678 |
| SERINC5 | serine incorporator 5 | 0.0304182 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0300473 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0293756 |
| ERBIN | erbb2 interacting protein | 0.0290907 |
| NF1 | neurofibromin 1 | 0.0290107 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0283235 |
| OGA | O-GlcNAcase | 0.0281217 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0264359 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0263413 |
| RAD51B | RAD51 paralog B | 0.0263152 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0260489 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0258241 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0245728 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.024212 |
| DUSP10 | dual specificity phosphatase 10 | 0.0241717 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0239905 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0238464 |
| NEBL | nebulette | 0.0238079 |
| SPATA13 | spermatogenesis associated 13 | 0.0235629 |
| APP | amyloid beta (A4) precursor protein | 0.0235156 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0234111 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0231489 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0229454 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0227122 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0226421 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0225381 |
| ATXN1 | ataxin 1 | 0.0224517 |
| IGF2R | insulin-like growth factor 2 receptor | 0.0222934 |
| SLK | STE20-like kinase | 0.0222375 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0222003 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0221104 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0220911 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0220651 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0220172 |
| RBM26 | RNA binding motif protein 26 | 0.021942 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.021923 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0218895 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0217488 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0216862 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0213924 |
| RAB1A | RAB1A, member RAS oncogene family | 0.021307 |
| TJP1 | tight junction protein 1 | 0.0212232 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0211872 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0211146 |
| ATP11A | ATPase, class VI, type 11A | 0.0211094 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0210037 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0206269 |
| RBM33 | RNA binding motif protein 33 | 0.0201697 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0201458 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0199011 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0198465 |
| JMJD1C | jumonji domain containing 1C | 0.0198438 |
| PMM2 | phosphomannomutase 2 | 0.0196822 |
| JAK1 | Janus kinase 1 | 0.0195992 |
| SUCO | SUN domain containing ossification factor | 0.0195037 |
| DIAPH1 | diaphanous-related formin 1 | 0.0194199 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0194157 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0192172 |
| CEP95 | centrosomal protein 95kDa | 0.0191585 |
| PPARGC1A | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha | 0.0191082 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0190261 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0189332 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0189247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.137028 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.1198 |
| LCN2 | lipocalin 2 | -0.10161 |
| PTMA | prothymosin, alpha | -0.0825313 |
| B2M | beta-2-microglobulin | -0.0761324 |
| HLA-B | major histocompatibility complex, class I, B | -0.0688156 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0684719 |
| TXNIP | thioredoxin interacting protein | -0.0679697 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0637106 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0566027 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0535683 |
| EGR1 | early growth response 1 | -0.0520267 |
| MT2A | metallothionein 2A | -0.0512663 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0496659 |
| FTL | ferritin, light polypeptide | -0.0494055 |
| PERP | PERP, TP53 apoptosis effector | -0.0476456 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.046587 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0461157 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0459247 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0456383 |
| PKM | pyruvate kinase, muscle | -0.0448338 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0389936 |
| HLA-A | major histocompatibility complex, class I, A | -0.0381664 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.037505 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0372151 |
| HLA-E | major histocompatibility complex, class I, E | -0.0359856 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0352133 |
| KRT19 | keratin 19, type I | -0.0351831 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0349277 |
| S100A10 | S100 calcium binding protein A10 | -0.034443 |
| TMSB10 | thymosin beta 10 | -0.0339557 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0333193 |
| H1-0 | H1.0 linker histone | -0.032464 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.032406 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0320799 |
| POTEF | POTE ankyrin domain family, member F | -0.0308524 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0303387 |
| IRF1 | interferon regulatory factor 1 | -0.0295802 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289239 |
| UBC | ubiquitin C | -0.0284207 |
| RPL35A | ribosomal protein L35a | -0.0283645 |
| ABLIM1 | actin binding LIM protein 1 | -0.0283017 |
| TPI1 | triosephosphate isomerase 1 | -0.0282731 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.028249 |
| S100A6 | S100 calcium binding protein A6 | -0.0281896 |
| H3-3B | H3.3 histone B | -0.0281169 |
| CALR | calreticulin | -0.0278469 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0276149 |
| MT1X | metallothionein 1X | -0.0270492 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0267586 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0266759 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0264189 |
| RPL23 | ribosomal protein L23 | -0.0264042 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0261229 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0261057 |
| NUCB2 | nucleobindin 2 | -0.0255817 |
| HLA-C | major histocompatibility complex, class I, C | -0.0255573 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0244691 |
| EFNB2 | ephrin-B2 | -0.0240913 |
| LDHA | lactate dehydrogenase A | -0.0239369 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0237616 |
| RPS19 | ribosomal protein S19 | -0.0232376 |
| PGK1 | phosphoglycerate kinase 1 | -0.0224877 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0224194 |
| CTSD | cathepsin D | -0.0223126 |
| AGR2 | anterior gradient 2 | -0.0222526 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0221206 |
| CST3 | cystatin C | -0.0215997 |
| ENO1 | enolase 1, (alpha) | -0.0214745 |
| GNAS | GNAS complex locus | -0.0214566 |
| MKI67 | marker of proliferation Ki-67 | -0.0209517 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.020856 |
| CSTB | cystatin B (stefin B) | -0.0203842 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0203197 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | -0.020066 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0197385 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0195728 |
| EPHB2 | EPH receptor B2 | -0.0192555 |
| GPX2 | glutathione peroxidase 2 | -0.0191275 |
| S100A9 | S100 calcium binding protein A9 | -0.0190449 |
| CXXC5 | CXXC finger protein 5 | -0.0190109 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.01889 |
| CTSB | cathepsin B | -0.0186356 |
| MX2 | MX dynamin-like GTPase 2 | -0.0183838 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.018359 |
| RUNX1 | runt-related transcription factor 1 | -0.0182981 |
| MLEC | malectin | -0.0182693 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0182557 |
| XAF1 | XIAP associated factor 1 | -0.0179399 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0179218 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0178715 |
| TUBA1B | tubulin, alpha 1b | -0.0175089 |
| ADM | adrenomedullin | -0.0174961 |
| TOB1 | transducer of ERBB2, 1 | -0.017476 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0172972 |
| RPL19 | ribosomal protein L19 | -0.0172336 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0171739 |
| EHF | ets homologous factor | -0.017153 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.0170714 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0169985 |
