| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | crizotinib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the crizotinib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MEF2A | myocyte enhancer factor 2A | 0.140323 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.131157 |
| CLU | clusterin | 0.113592 |
| OGA | O-GlcNAcase | 0.109249 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.106223 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0877209 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0864517 |
| RBM39 | RNA binding motif protein 39 | 0.0857326 |
| PGK1 | phosphoglycerate kinase 1 | 0.0847205 |
| ITGA6 | integrin, alpha 6 | 0.0749368 |
| ENO1 | enolase 1, (alpha) | 0.0677049 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0676063 |
| GOLGA4 | golgin A4 | 0.0671548 |
| KIAA1217 | KIAA1217 | 0.0659568 |
| B2M | beta-2-microglobulin | 0.0658844 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0655516 |
| TMSB4X | thymosin beta 4, X-linked | 0.0603709 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.059317 |
| STC1 | stanniocalcin 1 | 0.0593145 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0564294 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0561862 |
| ZNF292 | zinc finger protein 292 | 0.0554169 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0552931 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0546707 |
| RNF145 | ring finger protein 145 | 0.0545711 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0542713 |
| SQLE | squalene epoxidase | 0.0539264 |
| DSTN | destrin (actin depolymerizing factor) | 0.0533252 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0526158 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0520478 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0510136 |
| MYOF | myoferlin | 0.0504409 |
| SLK | STE20-like kinase | 0.050439 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0494429 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0494251 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0494145 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0482896 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0482196 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0464166 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0462242 |
| EZR | ezrin | 0.0461478 |
| CUL4B | cullin 4B | 0.0461088 |
| SPAG9 | sperm associated antigen 9 | 0.045946 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0458223 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.045544 |
| PTK2 | protein tyrosine kinase 2 | 0.0454765 |
| LDHA | lactate dehydrogenase A | 0.0440457 |
| SUCO | SUN domain containing ossification factor | 0.0440203 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.043688 |
| TOP1 | topoisomerase (DNA) I | 0.0436381 |
| ARRDC3 | arrestin domain containing 3 | 0.043481 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0433974 |
| NDRG1 | N-myc downstream regulated 1 | 0.0424324 |
| ANLN | anillin, actin binding protein | 0.0421832 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0418464 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0418266 |
| QKI | QKI, KH domain containing, RNA binding | 0.0414988 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0414381 |
| SERINC3 | serine incorporator 3 | 0.0407612 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0406778 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0406635 |
| FNIP1 | folliculin interacting protein 1 | 0.0403618 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.0400353 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0400324 |
| RLF | rearranged L-myc fusion | 0.0389567 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0387727 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0383678 |
| RTN4 | reticulon 4 | 0.0376969 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0372617 |
| MATR3 | matrin 3 | 0.0368728 |
| USP3 | ubiquitin specific peptidase 3 | 0.0367147 |
| YBX3 | Y box binding protein 3 | 0.0366697 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0365141 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0359634 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0357198 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0352263 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0350832 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0350204 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0349281 |
| RNF19B | ring finger protein 19B | 0.0348118 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0347959 |
| KRT17 | keratin 17, type I | 0.0344801 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0343645 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.034247 |
| SBF2 | SET binding factor 2 | 0.0341755 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0341218 |
| ANKH | ANKH inorganic pyrophosphate transport regulator | 0.0339988 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0339737 |
| RIOK3 | RIO kinase 3 | 0.0338267 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0334994 |
| SMAD3 | SMAD family member 3 | 0.0331303 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.032832 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0327644 |
| MYO10 | myosin X | 0.0326821 |
| PHF21A | PHD finger protein 21A | 0.0326616 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0326007 |
| SLMAP | sarcolemma associated protein | 0.0325489 |
| OSBPL6 | oxysterol binding protein-like 6 | 0.0324938 |
| FAM3C | family with sequence similarity 3, member C | 0.0322915 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.03227 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.207734 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.126724 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.106004 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0994997 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0993075 |
| INTS6 | integrator complex subunit 6 | -0.094992 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0879266 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0832915 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0788716 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0769717 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0761088 |
| RASAL2 | RAS protein activator like 2 | -0.0708063 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0707478 |
| RIGI | RNA sensor RIG-I | -0.0642001 |
| HMGA2 | high mobility group AT-hook 2 | -0.0625146 |
| SULF1 | sulfatase 1 | -0.0584562 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0578017 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0542271 |
| PALLD | palladin, cytoskeletal associated protein | -0.0531229 |
| SULF2 | sulfatase 2 | -0.0528172 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0523517 |
| RAD51B | RAD51 paralog B | -0.0484273 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0464265 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0450227 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0439088 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0434132 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0431242 |
| LAMC2 | laminin, gamma 2 | -0.0420156 |
| DGKH | diacylglycerol kinase, eta | -0.040601 |
| MECOM | MDS1 and EVI1 complex locus | -0.0405142 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0402234 |
| LAMA5 | laminin, alpha 5 | -0.0385138 |
| IFI44L | interferon-induced protein 44-like | -0.0375009 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0371926 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0370745 |
| HDAC9 | histone deacetylase 9 | -0.0363313 |
| MTSS1 | metastasis suppressor 1 | -0.0360026 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0352874 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0351808 |
| ACTN4 | actinin, alpha 4 | -0.0351666 |
| EXOC4 | exocyst complex component 4 | -0.0336323 |
| VCL | vinculin | -0.0330316 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0327053 |
| CDK6 | cyclin-dependent kinase 6 | -0.0325775 |
| PRSS23 | protease, serine, 23 | -0.0323898 |
| PLCE1 | phospholipase C, epsilon 1 | -0.0309163 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0308627 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0307601 |
| SMYD3 | SET and MYND domain containing 3 | -0.0304496 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0303498 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0301879 |
| TNS3 | tensin 3 | -0.0298271 |
| CORO2A | coronin, actin binding protein, 2A | -0.0298043 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0297408 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0291444 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0285808 |
| EGFR | epidermal growth factor receptor | -0.0285531 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0284594 |
| CMIP | c-Maf inducing protein | -0.0276525 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0267722 |
| IFI44 | interferon-induced protein 44 | -0.0265973 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0264773 |
| PODXL | podocalyxin-like | -0.0263701 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0261393 |
| KIAA1549L | KIAA1549-like | -0.0259788 |
| RHOJ | ras homolog family member J | -0.0257564 |
| CUX1 | cut-like homeobox 1 | -0.0254617 |
| MTAP | methylthioadenosine phosphorylase | -0.0253262 |
| NCKAP5 | NCK-associated protein 5 | -0.0252308 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0249549 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0247902 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0247266 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0247199 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0246774 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0246515 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0244345 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0242003 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0238098 |
| ATM | ATM serine/threonine kinase | -0.0237307 |
| HELZ2 | helicase with zinc finger 2, transcriptional coactivator | -0.0236982 |
| PLXNA2 | plexin A2 | -0.023356 |
| TENM4 | teneurin transmembrane protein 4 | -0.0231361 |
| RCOR1 | REST corepressor 1 | -0.0229333 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0225813 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0225305 |
| RRBP1 | ribosome binding protein 1 | -0.022459 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0223226 |
| RNF213 | ring finger protein 213 | -0.022288 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0222865 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0219158 |
| EGR1 | early growth response 1 | -0.0217911 |
| KLF12 | Kruppel-like factor 12 | -0.0217702 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0216906 |
| COL5A1 | collagen, type V, alpha 1 | -0.0216327 |
| RNF217 | ring finger protein 217 | -0.021617 |
| SETX | senataxin | -0.0214528 |
| SIK3 | SIK family kinase 3 | -0.0213369 |
| UBAP2 | ubiquitin associated protein 2 | -0.0209662 |
| MT2A | metallothionein 2A | -0.0208727 |
| MXRA5 | matrix-remodelling associated 5 | -0.0207132 |
