| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | crizotinib perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the crizotinib_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SDK1 | sidekick cell adhesion molecule 1 | 0.162209 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.10723 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0894707 |
| FAM13A | family with sequence similarity 13, member A | 0.089227 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0881376 |
| PCBP2 | poly(rC) binding protein 2 | 0.0860502 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0820711 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0809994 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0795407 |
| USP34 | ubiquitin specific peptidase 34 | 0.0732939 |
| NAV2 | neuron navigator 2 | 0.0699162 |
| RBM39 | RNA binding motif protein 39 | 0.069596 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.0662153 |
| PRELID2 | PRELI domain containing 2 | 0.0659396 |
| EFNA5 | ephrin-A5 | 0.0652675 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0650078 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0629006 |
| CDH13 | cadherin 13 | 0.0619629 |
| PTK2 | protein tyrosine kinase 2 | 0.0602734 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0591649 |
| MEF2A | myocyte enhancer factor 2A | 0.0591464 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0584592 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0577431 |
| USP3 | ubiquitin specific peptidase 3 | 0.0564295 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0563086 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0553883 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0549473 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0535678 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.051873 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0517103 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0511723 |
| ZNF292 | zinc finger protein 292 | 0.0510417 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0506933 |
| NGLY1 | N-glycanase 1 | 0.0505568 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0499388 |
| HELZ | helicase with zinc finger | 0.0498416 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.049827 |
| ANO6 | anoctamin 6 | 0.0486704 |
| OGA | O-GlcNAcase | 0.0482744 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0479805 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0454937 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0446791 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0444487 |
| GOLGA4 | golgin A4 | 0.0443856 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0441514 |
| TMSB4X | thymosin beta 4, X-linked | 0.0436432 |
| RUNX1 | runt-related transcription factor 1 | 0.043374 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0433563 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0432977 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0423318 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0402736 |
| PARD3 | par-3 family cell polarity regulator | 0.0401799 |
| JMJD1C | jumonji domain containing 1C | 0.0400684 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0398896 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0394329 |
| ANXA1 | annexin A1 | 0.0394286 |
| SMAD3 | SMAD family member 3 | 0.039401 |
| NBAS | neuroblastoma amplified sequence | 0.0391912 |
| AHR | aryl hydrocarbon receptor | 0.039184 |
| ATP13A3 | ATPase type 13A3 | 0.0389099 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.038741 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.038369 |
| XPO1 | exportin 1 | 0.0381065 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0377893 |
| SUCO | SUN domain containing ossification factor | 0.0376454 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.037549 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0370446 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0368813 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0368258 |
| SPAG9 | sperm associated antigen 9 | 0.035727 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0354542 |
| FMNL2 | formin-like 2 | 0.0352592 |
| ADD3 | adducin 3 (gamma) | 0.0346446 |
| BBX | bobby sox homolog (Drosophila) | 0.0344573 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0344036 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0343622 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0342982 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0342887 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0341247 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0339931 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0339658 |
| RNF145 | ring finger protein 145 | 0.0339561 |
| COG5 | component of oligomeric golgi complex 5 | 0.0339212 |
| MYO1B | myosin IB | 0.0336675 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0336664 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | 0.0335662 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0333807 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0331385 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0326818 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0326375 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.0324351 |
| SBF2 | SET binding factor 2 | 0.0323984 |
| QKI | QKI, KH domain containing, RNA binding | 0.0323002 |
| RIOK3 | RIO kinase 3 | 0.0322164 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0321656 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0321069 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0318411 |
| GPC6 | glypican 6 | 0.0316388 |
| TXNRD1 | thioredoxin reductase 1 | 0.0311515 |
| NHSL1 | NHS-like 1 | 0.0308231 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.153908 |
| CD44 | CD44 molecule (Indian blood group) | -0.14597 |
| TMSB10 | thymosin beta 10 | -0.132341 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.118851 |
| OSMR | oncostatin M receptor | -0.0915362 |
| GLCCI1 | glucocorticoid induced 1 | -0.0843447 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0822852 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.082268 |
| LOX | lysyl oxidase | -0.0814676 |
| NTN4 | netrin 4 | -0.0771518 |
| MT2A | metallothionein 2A | -0.0741777 |
| EGR1 | early growth response 1 | -0.0708592 |
| VIM | vimentin | -0.0620173 |
| TNNC1 | troponin C type 1 (slow) | -0.0599224 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0568368 |
| FTL | ferritin, light polypeptide | -0.0495708 |
| IER3 | immediate early response 3 | -0.0493226 |
| STC1 | stanniocalcin 1 | -0.048792 |
| KYNU | kynureninase | -0.0448704 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0431457 |
| PTMA | prothymosin, alpha | -0.0429137 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0411936 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0409555 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0402383 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.039995 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0399788 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0386109 |
| TGM2 | transglutaminase 2 | -0.0382016 |
| RPS19 | ribosomal protein S19 | -0.0371535 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.035407 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0350333 |
| IL1R1 | interleukin 1 receptor, type I | -0.0342388 |
| RPL36 | ribosomal protein L36 | -0.0326381 |
| KSR1 | kinase suppressor of ras 1 | -0.0323521 |
| RAD51B | RAD51 paralog B | -0.0323022 |
| RPLP1 | ribosomal protein, large, P1 | -0.0316263 |
| RPL32 | ribosomal protein L32 | -0.0315152 |
| HMGA2 | high mobility group AT-hook 2 | -0.0311859 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0311598 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0309713 |
| BPTF | bromodomain PHD finger transcription factor | -0.0306583 |
| RPL35A | ribosomal protein L35a | -0.0301718 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0301264 |
| MX2 | MX dynamin-like GTPase 2 | -0.0300207 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.029862 |
| RPLP2 | ribosomal protein, large, P2 | -0.0287669 |
| RPL28 | ribosomal protein L28 | -0.0285472 |
| RPL31 | ribosomal protein L31 | -0.0276395 |
| MAP1B | microtubule-associated protein 1B | -0.0272407 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0267099 |
| FN1 | fibronectin 1 | -0.0262277 |
| RPL23 | ribosomal protein L23 | -0.0258491 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0257947 |
| RPS13 | ribosomal protein S13 | -0.0255575 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0253667 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0252579 |
| VCL | vinculin | -0.0252348 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0249669 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0249149 |
| FAM20C | family with sequence similarity 20, member C | -0.0245458 |
| GLIS3 | GLIS family zinc finger 3 | -0.0244591 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0239905 |
| FHL2 | four and a half LIM domains 2 | -0.0235944 |
| AADAC | arylacetamide deacetylase | -0.0234489 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.0234073 |
| RPS29 | ribosomal protein S29 | -0.0232181 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.023072 |
| HTRA3 | HtrA serine peptidase 3 | -0.0230357 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0227273 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0223865 |
| RNF24 | ring finger protein 24 | -0.0223675 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0222958 |
| NDRG1 | N-myc downstream regulated 1 | -0.0222503 |
| RPL19 | ribosomal protein L19 | -0.0217875 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0214534 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0211056 |
| HLA-B | major histocompatibility complex, class I, B | -0.0208629 |
| EVA1C | eva-1 homolog C (C. elegans) | -0.0208003 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0206325 |
| SYAP1 | synapse associated protein 1 | -0.0203112 |
| RIGI | RNA sensor RIG-I | -0.0202965 |
| VDAC1 | voltage-dependent anion channel 1 | -0.020143 |
| STK38L | serine/threonine kinase 38 like | -0.0200069 |
| S100A6 | S100 calcium binding protein A6 | -0.0199377 |
| S100A9 | S100 calcium binding protein A9 | -0.0197797 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0194855 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.01933 |
| RPS8 | ribosomal protein S8 | -0.0193144 |
| RPS27 | ribosomal protein S27 | -0.019264 |
| VRK2 | vaccinia related kinase 2 | -0.01925 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0191783 |
| CLMP | CXADR-like membrane protein | -0.0188452 |
| RPS6 | ribosomal protein S6 | -0.0188064 |
| KLF6 | Kruppel-like factor 6 | -0.018729 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0187078 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0185633 |
| RPL18 | ribosomal protein L18 | -0.018186 |
| ANGPTL4 | angiopoietin-like 4 | -0.0181227 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0178582 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0178203 |
