| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | crizotinib perturbation in NCI-H2347 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the crizotinib_NCI-H2347 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.0998893 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0730167 |
| PTK2 | protein tyrosine kinase 2 | 0.0643389 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0622522 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0596921 |
| ZNF292 | zinc finger protein 292 | 0.0591436 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0580988 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.056045 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0545779 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0543568 |
| NAV2 | neuron navigator 2 | 0.0529637 |
| RYBP | RING1 and YY1 binding protein | 0.0517746 |
| DTNA | dystrobrevin, alpha | 0.0501327 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0498825 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0494729 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.048536 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0480697 |
| MYO5B | myosin VB | 0.0478704 |
| MEF2A | myocyte enhancer factor 2A | 0.0461248 |
| PCBP2 | poly(rC) binding protein 2 | 0.0446362 |
| MSN | moesin | 0.044255 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0441963 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0440111 |
| OCLN | occludin | 0.0415343 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0414711 |
| FHIT | fragile histidine triad | 0.0413737 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0411332 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0403958 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.040324 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0391743 |
| RAP2B | RAP2B, member of RAS oncogene family | 0.0377832 |
| CCNL1 | cyclin L1 | 0.0367922 |
| DSPP | dentin sialophosphoprotein | 0.0363469 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0359874 |
| EZR | ezrin | 0.0355292 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0339515 |
| TPM3 | tropomyosin 3 | 0.0327217 |
| HSPA8 | heat shock 70kDa protein 8 | 0.031945 |
| VGLL3 | vestigial-like family member 3 | 0.0315154 |
| MYO6 | myosin VI | 0.0314899 |
| USP3 | ubiquitin specific peptidase 3 | 0.0307039 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0302148 |
| MACC1 | metastasis associated in colon cancer 1 | 0.030173 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0297825 |
| NPTN | neuroplastin | 0.0294105 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0294019 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0286353 |
| ARRDC3 | arrestin domain containing 3 | 0.0283556 |
| ANXA11 | annexin A11 | 0.0280005 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0276195 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0271952 |
| SNX9 | sorting nexin 9 | 0.0269023 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0267508 |
| RPL14 | ribosomal protein L14 | 0.0266774 |
| KIAA1217 | KIAA1217 | 0.0262356 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0261761 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.026061 |
| VEGFA | vascular endothelial growth factor A | 0.0259547 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.025843 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0249574 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0248524 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0246534 |
| PGBD5 | piggyBac transposable element derived 5 | 0.0244106 |
| RPS12 | ribosomal protein S12 | 0.0239841 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0239567 |
| ANO6 | anoctamin 6 | 0.023587 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0234505 |
| RPL3 | ribosomal protein L3 | 0.0233048 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0232178 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0231868 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0231631 |
| MSMO1 | methylsterol monooxygenase 1 | 0.0230462 |
| EFNA5 | ephrin-A5 | 0.0229131 |
| RPS2 | ribosomal protein S2 | 0.0228617 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0227332 |
| IRF6 | interferon regulatory factor 6 | 0.0225304 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0222585 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0222085 |
| SUCO | SUN domain containing ossification factor | 0.0220325 |
| NCKAP1 | NCK-associated protein 1 | 0.0219998 |
| MTMR3 | myotubularin related protein 3 | 0.0218992 |
| BRD2 | bromodomain containing 2 | 0.0218656 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0218544 |
| MCL1 | myeloid cell leukemia 1 | 0.0216418 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0216024 |
| CNKSR3 | CNKSR family member 3 | 0.0214035 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0214009 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0213664 |
| TXNRD1 | thioredoxin reductase 1 | 0.021337 |
| UPP1 | uridine phosphorylase 1 | 0.0211516 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0210985 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0210951 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | 0.0210761 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.020805 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.020648 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0206384 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0203747 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.020243 |
| DIAPH1 | diaphanous-related formin 1 | 0.0199735 |
| ITGAV | integrin, alpha V | 0.0199693 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.230588 |
| TMSB10 | thymosin beta 10 | -0.15838 |
| ACTG1 | actin gamma 1 | -0.14803 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.140137 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129656 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.117932 |
| FTL | ferritin, light polypeptide | -0.111174 |
| S100A6 | S100 calcium binding protein A6 | -0.107071 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0943011 |
| LAMB3 | laminin, beta 3 | -0.0927032 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0841352 |
| POTEF | POTE ankyrin domain family, member F | -0.0808568 |
| FN1 | fibronectin 1 | -0.0773368 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0766449 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0711375 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0685204 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0668636 |
| HLA-A | major histocompatibility complex, class I, A | -0.0639441 |
| S100A10 | S100 calcium binding protein A10 | -0.0627794 |
| CD2AP | CD2-associated protein | -0.0622356 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0619918 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0618859 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0614384 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0600736 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.059981 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0587898 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0571951 |
| RASAL2 | RAS protein activator like 2 | -0.0568597 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0549513 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0536811 |
| GNAS | GNAS complex locus | -0.0536228 |
| TPM4 | tropomyosin 4 | -0.0513086 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0510722 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0510463 |
| RPL35A | ribosomal protein L35a | -0.0505012 |
| SACK1A | scaffolding CK1 anchoring protein A | -0.0504084 |
| UBC | ubiquitin C | -0.0495005 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0492568 |
| FBXO32 | F-box protein 32 | -0.0491624 |
| CCND1 | cyclin D1 | -0.049101 |
| EPCAM | epithelial cell adhesion molecule | -0.0486019 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0482888 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.047548 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0474854 |
| MT2A | metallothionein 2A | -0.0465126 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0457262 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0452734 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.045239 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0449349 |
| HLA-B | major histocompatibility complex, class I, B | -0.0445023 |
| ARF1 | ADP-ribosylation factor 1 | -0.0439281 |
| CAVIN1 | caveolae associated protein 1 | -0.0427698 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0421458 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0420839 |
| LAMC2 | laminin, gamma 2 | -0.04164 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0404765 |
| RBM25 | RNA binding motif protein 25 | -0.0403352 |
| CSTB | cystatin B (stefin B) | -0.039197 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0380238 |
| KRT7 | keratin 7, type II | -0.0380104 |
| ANXA2 | annexin A2 | -0.0379982 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0377297 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0375874 |
| RPLP1 | ribosomal protein, large, P1 | -0.0368874 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0367705 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0366659 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0365426 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0364127 |
| PGK1 | phosphoglycerate kinase 1 | -0.0362428 |
| HLA-E | major histocompatibility complex, class I, E | -0.0361569 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0359783 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0359598 |
| H3-3B | H3.3 histone B | -0.0359012 |
| RPL34 | ribosomal protein L34 | -0.0354402 |
| JMJD1C | jumonji domain containing 1C | -0.0352066 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0351706 |
| S100A9 | S100 calcium binding protein A9 | -0.034907 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0345496 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0344253 |
| SLMAP | sarcolemma associated protein | -0.0341452 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0340221 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0338741 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0337524 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0333761 |
| LMO7 | LIM domain 7 | -0.033188 |
| FRMD5 | FERM domain containing 5 | -0.0327398 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0324324 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.032415 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0318182 |
| TPI1 | triosephosphate isomerase 1 | -0.0317417 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0316956 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0310319 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0308372 |
| CD63 | CD63 molecule | -0.0306494 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0301227 |
| TMEM263 | transmembrane protein 263 | -0.0298808 |
| ASPH | aspartate beta-hydroxylase | -0.0296476 |
| RPL8 | ribosomal protein L8 | -0.0292359 |
| FLNB | filamin B, beta | -0.0285178 |
| RPS29 | ribosomal protein S29 | -0.0284271 |
