| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | crizotinib perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the crizotinib_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.15066 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.147351 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.140297 |
| NAV2 | neuron navigator 2 | 0.132804 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.111931 |
| OGA | O-GlcNAcase | 0.100125 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0875037 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0863492 |
| ZNF292 | zinc finger protein 292 | 0.084063 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0770091 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.074885 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0744084 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0736283 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0735054 |
| SPAG9 | sperm associated antigen 9 | 0.073087 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0725319 |
| ATP13A3 | ATPase type 13A3 | 0.0703364 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0701853 |
| CADM1 | cell adhesion molecule 1 | 0.068751 |
| FN1 | fibronectin 1 | 0.0680931 |
| ANLN | anillin, actin binding protein | 0.0654664 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0654322 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0647848 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0601652 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0571034 |
| SNX9 | sorting nexin 9 | 0.0564675 |
| MYOF | myoferlin | 0.0551023 |
| RBM39 | RNA binding motif protein 39 | 0.0545386 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0538537 |
| JMJD1C | jumonji domain containing 1C | 0.053456 |
| HELZ | helicase with zinc finger | 0.0534271 |
| CENPF | centromere protein F, 350/400kDa | 0.053377 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0513588 |
| ERBIN | erbb2 interacting protein | 0.0479038 |
| APP | amyloid beta (A4) precursor protein | 0.0472549 |
| PGK1 | phosphoglycerate kinase 1 | 0.0468981 |
| AFDN | afadin, adherens junction formation factor | 0.0457995 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.0455495 |
| MKI67 | marker of proliferation Ki-67 | 0.0453379 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0450249 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0448483 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0446057 |
| MATR3 | matrin 3 | 0.0443764 |
| SBF2 | SET binding factor 2 | 0.0443621 |
| TMSB4X | thymosin beta 4, X-linked | 0.0428733 |
| RTN4 | reticulon 4 | 0.0424426 |
| NEK7 | NIMA-related kinase 7 | 0.0423685 |
| ANXA2 | annexin A2 | 0.0422394 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0422375 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0416949 |
| DENND5A | DENN/MADD domain containing 5A | 0.0407105 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0402719 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0401899 |
| MSN | moesin | 0.0401574 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.039537 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0394776 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0389351 |
| PUM2 | pumilio RNA-binding family member 2 | 0.038896 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0387627 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0386835 |
| KIF4A | kinesin family member 4A | 0.0385122 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0383408 |
| GOLGA4 | golgin A4 | 0.0382762 |
| WTAP | Wilms tumor 1 associated protein | 0.0378059 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.037777 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0375994 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0364917 |
| DST | dystonin | 0.0362699 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.035968 |
| FMNL2 | formin-like 2 | 0.0349748 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0346008 |
| DIAPH3 | diaphanous-related formin 3 | 0.0343724 |
| TXNRD1 | thioredoxin reductase 1 | 0.0342419 |
| SMAD3 | SMAD family member 3 | 0.0338945 |
| EZR | ezrin | 0.0336002 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0335968 |
| ARRDC3 | arrestin domain containing 3 | 0.0333948 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0333455 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0330194 |
| NUP153 | nucleoporin 153kDa | 0.0325645 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0321224 |
| PHIP | pleckstrin homology domain interacting protein | 0.0321118 |
| TPX2 | TPX2, microtubule-associated | 0.0318567 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0318185 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.031797 |
| NCKAP1 | NCK-associated protein 1 | 0.0315587 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0315111 |
| FNIP1 | folliculin interacting protein 1 | 0.0312189 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0311803 |
| STAG2 | stromal antigen 2 | 0.0310487 |
| B2M | beta-2-microglobulin | 0.0310353 |
| QKI | QKI, KH domain containing, RNA binding | 0.0308735 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0308705 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0306213 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0306131 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0304667 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0304254 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0303066 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0302951 |
| PDE10A | phosphodiesterase 10A | 0.0301132 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129225 |
| FTL | ferritin, light polypeptide | -0.10119 |
| VIM | vimentin | -0.093434 |
| TMSB10 | thymosin beta 10 | -0.092954 |
| MT2A | metallothionein 2A | -0.0913205 |
| HLA-B | major histocompatibility complex, class I, B | -0.0738973 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0648579 |
| GLIS3 | GLIS family zinc finger 3 | -0.0621155 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0617286 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0599679 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0574923 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0533866 |
| RPLP2 | ribosomal protein, large, P2 | -0.0530326 |
| IER3 | immediate early response 3 | -0.0486865 |
| NDRG1 | N-myc downstream regulated 1 | -0.0458491 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0455359 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0446804 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0442412 |
| RPL37A | ribosomal protein L37a | -0.0437694 |
| RPS3 | ribosomal protein S3 | -0.0426469 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0414024 |
| RPL35A | ribosomal protein L35a | -0.0412187 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0408697 |
| INTS6 | integrator complex subunit 6 | -0.0406963 |
| RPS19 | ribosomal protein S19 | -0.0403982 |
| HMGA2 | high mobility group AT-hook 2 | -0.0381382 |
| RPL19 | ribosomal protein L19 | -0.0379364 |
| EGR1 | early growth response 1 | -0.0376415 |
| RPL23 | ribosomal protein L23 | -0.0367848 |
| RPLP1 | ribosomal protein, large, P1 | -0.0361161 |
| RPS8 | ribosomal protein S8 | -0.0356426 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0355499 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0342115 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0340706 |
| HLA-A | major histocompatibility complex, class I, A | -0.0335912 |
| PTMA | prothymosin, alpha | -0.0329063 |
| RPS12 | ribosomal protein S12 | -0.0324549 |
| FRMD4A | FERM domain containing 4A | -0.0320006 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0319406 |
| RPL36A | ribosomal protein L36a | -0.0316801 |
| COL5A1 | collagen, type V, alpha 1 | -0.0314146 |
| RPL9 | ribosomal protein L9 | -0.0310739 |
| RPS6 | ribosomal protein S6 | -0.0309212 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0303031 |
| RPS23 | ribosomal protein S23 | -0.0300021 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0296676 |
| RPS24 | ribosomal protein S24 | -0.0294089 |
| RPL36 | ribosomal protein L36 | -0.0293035 |
| RNF213 | ring finger protein 213 | -0.0281398 |
| RPL12 | ribosomal protein L12 | -0.0278778 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0275991 |
| S100A9 | S100 calcium binding protein A9 | -0.0270993 |
| RPS10 | ribosomal protein S10 | -0.0269166 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0266474 |
| CTSD | cathepsin D | -0.0257782 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0253253 |
| RPL31 | ribosomal protein L31 | -0.0248606 |
| RPL28 | ribosomal protein L28 | -0.0245244 |
| RPS21 | ribosomal protein S21 | -0.024117 |
| RPS13 | ribosomal protein S13 | -0.0241132 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0239567 |
| TMEM132D | transmembrane protein 132D | -0.0238628 |
| RPS29 | ribosomal protein S29 | -0.0238523 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0237952 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0237591 |
| COL1A1 | collagen, type I, alpha 1 | -0.023644 |
| GPC6 | glypican 6 | -0.0235444 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0234836 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0233813 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0233235 |
| NAV1 | neuron navigator 1 | -0.0232821 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0226858 |
| RPL35 | ribosomal protein L35 | -0.0224492 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0223717 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0223346 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0221401 |
| RPL37 | ribosomal protein L37 | -0.0215883 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.021455 |
| RPL8 | ribosomal protein L8 | -0.0213414 |
| MT1X | metallothionein 1X | -0.0212003 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0210529 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0209702 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0207433 |
| RPL32 | ribosomal protein L32 | -0.0206365 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0204252 |
| HLA-E | major histocompatibility complex, class I, E | -0.0201913 |
| RPS27 | ribosomal protein S27 | -0.0198084 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0194837 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0193562 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.018787 |
| EGFR | epidermal growth factor receptor | -0.0186156 |
| TCEAL9 | transcription elongation factor A like 9 | -0.0184319 |
| CALR | calreticulin | -0.0183754 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0183728 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0183003 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0182289 |
| RPS14 | ribosomal protein S14 | -0.0182049 |
| HMGA1 | high mobility group AT-hook 1 | -0.0181721 |
| RPL26 | ribosomal protein L26 | -0.0180805 |
| RRBP1 | ribosome binding protein 1 | -0.017789 |
