| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | crizotinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the crizotinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0571593 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0552905 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0519225 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0471562 |
| ZNF292 | zinc finger protein 292 | 0.0471383 |
| TXNRD1 | thioredoxin reductase 1 | 0.0468044 |
| RBM39 | RNA binding motif protein 39 | 0.042701 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0414498 |
| YAP1 | Yes-associated protein 1 | 0.0406561 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0398133 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0372747 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0369373 |
| NUP58 | nucleoporin 58 | 0.0365814 |
| KIAA1328 | KIAA1328 | 0.0347043 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0339658 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0335464 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0326714 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0323737 |
| CEP250 | centrosomal protein 250kDa | 0.0315092 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0314306 |
| DNER | delta/notch-like EGF repeat containing | 0.0313555 |
| ANLN | anillin, actin binding protein | 0.0309753 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0309034 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0308351 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0303503 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | 0.0300523 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0296519 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.029324 |
| CENPF | centromere protein F, 350/400kDa | 0.0291698 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0290416 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0282786 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0276537 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0274962 |
| ECT2 | epithelial cell transforming 2 | 0.0268879 |
| GOLGA4 | golgin A4 | 0.0267401 |
| TPX2 | TPX2, microtubule-associated | 0.026736 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0267006 |
| ATXN1 | ataxin 1 | 0.0265793 |
| ATP13A3 | ATPase type 13A3 | 0.0264492 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0264077 |
| HELZ | helicase with zinc finger | 0.0260161 |
| SGO2 | shugoshin 2 | 0.0252557 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0252463 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0250665 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0250227 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0249231 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0244637 |
| AURKA | aurora kinase A | 0.0243817 |
| SPAG9 | sperm associated antigen 9 | 0.0243516 |
| RAB10 | RAB10, member RAS oncogene family | 0.0243117 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0237925 |
| HMGB2 | high mobility group box 2 | 0.0236825 |
| CLTC | clathrin, heavy chain (Hc) | 0.0233583 |
| YBX3 | Y box binding protein 3 | 0.0233413 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0232883 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0229851 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0227244 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0223189 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0222479 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0222004 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0220001 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0219913 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0217268 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0216856 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0216292 |
| NUP153 | nucleoporin 153kDa | 0.0215839 |
| RNF145 | ring finger protein 145 | 0.0215725 |
| DEK | DEK proto-oncogene | 0.0215119 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0214532 |
| FMNL2 | formin-like 2 | 0.0212239 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0211061 |
| CENPE | centromere protein E, 312kDa | 0.0209319 |
| TTK | TTK protein kinase | 0.0209263 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0207976 |
| CDK19 | cyclin-dependent kinase 19 | 0.0207009 |
| TMEM41B | transmembrane protein 41B | 0.0206645 |
| CANX | calnexin | 0.020644 |
| RLF | rearranged L-myc fusion | 0.0204464 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0203248 |
| SP3 | Sp3 transcription factor | 0.0203147 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0200923 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.020038 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0199987 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0199461 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0199113 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0198448 |
| MED13L | mediator complex subunit 13-like | 0.0198002 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0195416 |
| OXSR1 | oxidative stress responsive 1 | 0.0195191 |
| RPRD1B | regulation of nuclear pre-mRNA domain containing 1B | 0.019484 |
| KIF23 | kinesin family member 23 | 0.019264 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0191537 |
| PDS5B | PDS5 cohesin associated factor B | 0.0188665 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0188415 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.018808 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0187088 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0186354 |
| ETF1 | eukaryotic translation termination factor 1 | 0.0185055 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0185028 |
| OGA | O-GlcNAcase | 0.0184823 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.305218 |
| TMSB10 | thymosin beta 10 | -0.100818 |
| VIM | vimentin | -0.0979057 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0709473 |
| LOC112694756 | uncharaterized LOC112694756 | -0.056683 |
| PKM | pyruvate kinase, muscle | -0.0499871 |
| LDHA | lactate dehydrogenase A | -0.0497893 |
| ANGPTL4 | angiopoietin-like 4 | -0.0497707 |
| POTEF | POTE ankyrin domain family, member F | -0.042192 |
| PTMA | prothymosin, alpha | -0.0417944 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0402153 |
| RPL35A | ribosomal protein L35a | -0.0397685 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0377383 |
| PRKCA | protein kinase C, alpha | -0.0368229 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0351 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0349306 |
| MT2A | metallothionein 2A | -0.0348735 |
| RPL36 | ribosomal protein L36 | -0.0346253 |
| PRSS23 | protease, serine, 23 | -0.0346201 |
| ACTG1 | actin gamma 1 | -0.0341913 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0329336 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0325188 |
| HLA-B | major histocompatibility complex, class I, B | -0.0311309 |
| RAI14 | retinoic acid induced 14 | -0.0306929 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0306625 |
| HMGA2 | high mobility group AT-hook 2 | -0.0304331 |
| NDRG1 | N-myc downstream regulated 1 | -0.029977 |
| DST | dystonin | -0.0299597 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0296136 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0294125 |
| SVIL | supervillin | -0.0292869 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.029263 |
| TPI1 | triosephosphate isomerase 1 | -0.0291617 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0287195 |
| NALCN | sodium leak channel, non selective | -0.0285217 |
| ENO1 | enolase 1, (alpha) | -0.027916 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0276774 |
| RPS14 | ribosomal protein S14 | -0.0273774 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0269384 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0268731 |
| PODXL | podocalyxin-like | -0.0265216 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0257927 |
| H3-3B | H3.3 histone B | -0.025667 |
| RPLP1 | ribosomal protein, large, P1 | -0.0255646 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0255341 |
| EGR1 | early growth response 1 | -0.025365 |
| RBM25 | RNA binding motif protein 25 | -0.0252624 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0247971 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0244267 |
| RIGI | RNA sensor RIG-I | -0.0239054 |
| FTL | ferritin, light polypeptide | -0.0237148 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0234447 |
| RPL31 | ribosomal protein L31 | -0.0231072 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0228619 |
| S100A6 | S100 calcium binding protein A6 | -0.0228454 |
| S100A9 | S100 calcium binding protein A9 | -0.0226612 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0224405 |
| RPS27A | ribosomal protein S27a | -0.0224375 |
| BRD4 | bromodomain containing 4 | -0.0222019 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0221898 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0218154 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0217576 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0215412 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0212808 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0210134 |
| RPL12 | ribosomal protein L12 | -0.0207016 |
| RPL9 | ribosomal protein L9 | -0.0206044 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0205 |
| PRR16 | proline rich 16 | -0.020415 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0201269 |
| ZFHX3 | zinc finger homeobox 3 | -0.0200729 |
| PCED1B | PC-esterase domain containing 1B | -0.0200415 |
| RPS13 | ribosomal protein S13 | -0.0199695 |
| HLA-C | major histocompatibility complex, class I, C | -0.0199281 |
| RPL37 | ribosomal protein L37 | -0.0198596 |
| HLA-A | major histocompatibility complex, class I, A | -0.0197549 |
| LAMA5 | laminin, alpha 5 | -0.0196926 |
| CD44 | CD44 molecule (Indian blood group) | -0.0194968 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.01947 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0194237 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0194063 |
| RPLP0 | ribosomal protein, large, P0 | -0.01916 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0190077 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0189684 |
| PFN1 | profilin 1 | -0.0187457 |
| RPS15 | ribosomal protein S15 | -0.0186299 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0185473 |
| RPS21 | ribosomal protein S21 | -0.0185019 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0183822 |
| RPL23 | ribosomal protein L23 | -0.0183753 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0183735 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0183505 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0183474 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0183161 |
| RPL35 | ribosomal protein L35 | -0.0182808 |
| UBB | ubiquitin B | -0.0181957 |
| RPLP2 | ribosomal protein, large, P2 | -0.0180841 |
| SKIL | SKI-like proto-oncogene | -0.0180743 |
| RPS16 | ribosomal protein S16 | -0.0177528 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0177093 |
