| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | crizotinib perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the crizotinib_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | 0.166909 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.105115 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0960503 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0841589 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0826116 |
| AHR | aryl hydrocarbon receptor | 0.0813513 |
| CD109 | CD109 molecule | 0.0723702 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0719843 |
| ZNF292 | zinc finger protein 292 | 0.070891 |
| PTK2 | protein tyrosine kinase 2 | 0.0699066 |
| TXNRD1 | thioredoxin reductase 1 | 0.0669212 |
| OGA | O-GlcNAcase | 0.0661897 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0659871 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0659704 |
| SUCO | SUN domain containing ossification factor | 0.0659408 |
| RNF145 | ring finger protein 145 | 0.0575035 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0574704 |
| RBM39 | RNA binding motif protein 39 | 0.0566636 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0564263 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0561573 |
| RTN4 | reticulon 4 | 0.0560299 |
| TMEM156 | transmembrane protein 156 | 0.0558747 |
| NEK7 | NIMA-related kinase 7 | 0.0556061 |
| CENPF | centromere protein F, 350/400kDa | 0.0545014 |
| DST | dystonin | 0.0533509 |
| TPR | translocated promoter region, nuclear basket protein | 0.053037 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0519384 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0518349 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0514744 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0497094 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0489324 |
| SMAD3 | SMAD family member 3 | 0.0484058 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0476132 |
| GOLGA4 | golgin A4 | 0.0473201 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0472214 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0462782 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0460754 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0451785 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0442469 |
| FNBP1 | formin binding protein 1 | 0.0440289 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0436944 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0430221 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0429614 |
| JMJD1C | jumonji domain containing 1C | 0.0425054 |
| SPAG9 | sperm associated antigen 9 | 0.0423374 |
| HELZ | helicase with zinc finger | 0.0422133 |
| CUL3 | cullin 3 | 0.0417018 |
| COPA | coatomer protein complex, subunit alpha | 0.0414814 |
| SEPTIN7 | septin 7 | 0.0414524 |
| B2M | beta-2-microglobulin | 0.0414097 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0413176 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0409771 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0408036 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0403083 |
| XPO1 | exportin 1 | 0.0401089 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0394304 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0391731 |
| ETNK1 | ethanolamine kinase 1 | 0.0391627 |
| CDC73 | cell division cycle 73 | 0.0388627 |
| CARD16 | caspase recruitment domain family, member 16 | 0.0386238 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0384924 |
| SRPK2 | SRSF protein kinase 2 | 0.0384123 |
| WDR43 | WD repeat domain 43 | 0.0378913 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0373902 |
| MKI67 | marker of proliferation Ki-67 | 0.037341 |
| LIFR | leukemia inhibitory factor receptor alpha | 0.0372033 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0371537 |
| ERBIN | erbb2 interacting protein | 0.0367272 |
| DENND5B | DENN/MADD domain containing 5B | 0.0366656 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0360972 |
| ETV6 | ets variant 6 | 0.0357157 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0356785 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0355417 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0355342 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0354039 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0353143 |
| MATR3 | matrin 3 | 0.0351571 |
| ENAH | enabled homolog (Drosophila) | 0.0348579 |
| YME1L1 | YME1-like 1 ATPase | 0.0347867 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0347 |
| AFDN | afadin, adherens junction formation factor | 0.0346194 |
| FMNL2 | formin-like 2 | 0.0345132 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0341051 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.034016 |
| RUNX2 | runt-related transcription factor 2 | 0.0338421 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0337393 |
| TFG | TRK-fused gene | 0.0336701 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0336333 |
| EZR | ezrin | 0.0332696 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0331983 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0329771 |
| TPD52 | tumor protein D52 | 0.0329029 |
| RAB18 | RAB18, member RAS oncogene family | 0.0328255 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0327975 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0327708 |
| TXNIP | thioredoxin interacting protein | 0.0324716 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0323326 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0321048 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0320785 |
| ZNF148 | zinc finger protein 148 | 0.0320427 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.146694 |
| HMGA2 | high mobility group AT-hook 2 | -0.133886 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.13368 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.130969 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.094522 |
| FN1 | fibronectin 1 | -0.0893255 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0755072 |
| MT2A | metallothionein 2A | -0.0727985 |
| VCL | vinculin | -0.0709059 |
| PTMA | prothymosin, alpha | -0.0684974 |
| INTS6 | integrator complex subunit 6 | -0.0528354 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0478617 |
| TMSB10 | thymosin beta 10 | -0.0464254 |
| PALLD | palladin, cytoskeletal associated protein | -0.0462872 |
| HLA-B | major histocompatibility complex, class I, B | -0.0449738 |
| NDRG1 | N-myc downstream regulated 1 | -0.0387048 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.037501 |
| FTL | ferritin, light polypeptide | -0.0366346 |
| ACTG1 | actin gamma 1 | -0.0350031 |
| EGR1 | early growth response 1 | -0.0342135 |
| GLIS3 | GLIS family zinc finger 3 | -0.0330586 |
| ASPH | aspartate beta-hydroxylase | -0.0322993 |
| SYT1 | synaptotagmin I | -0.0299941 |
| SQSTM1 | sequestosome 1 | -0.02956 |
| LRRC23 | leucine rich repeat containing 23 | -0.027636 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0275585 |
| RPS19 | ribosomal protein S19 | -0.0274043 |
| AEBP2 | AE binding protein 2 | -0.0273937 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0273534 |
| RPL35A | ribosomal protein L35a | -0.0271538 |
| RPL37A | ribosomal protein L37a | -0.0268766 |
| RPS29 | ribosomal protein S29 | -0.0263996 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0263954 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0259354 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.025467 |
| LOXL2 | lysyl oxidase-like 2 | -0.024944 |
| S100A10 | S100 calcium binding protein A10 | -0.0246461 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0243835 |
| IER3 | immediate early response 3 | -0.0233947 |
| RPL31 | ribosomal protein L31 | -0.022973 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0224449 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0222741 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0217523 |
| RPLP2 | ribosomal protein, large, P2 | -0.0216833 |
| FAM20C | family with sequence similarity 20, member C | -0.0215547 |
| HLA-A | major histocompatibility complex, class I, A | -0.021391 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0211415 |
| DUSP6 | dual specificity phosphatase 6 | -0.0210854 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0206539 |
| MMP13 | matrix metallopeptidase 13 | -0.0201669 |
| RAI14 | retinoic acid induced 14 | -0.0201623 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0201422 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0199606 |
| RPS27 | ribosomal protein S27 | -0.0199105 |
| RPL12 | ribosomal protein L12 | -0.0198274 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0197117 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0195873 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0192593 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0192568 |
| RPS8 | ribosomal protein S8 | -0.0191409 |
| TGFB1 | transforming growth factor, beta 1 | -0.0189855 |
| FBN1 | fibrillin 1 | -0.0188327 |
| JUN | jun proto-oncogene | -0.0186769 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0186396 |
| TENM4 | teneurin transmembrane protein 4 | -0.018588 |
| RPL34 | ribosomal protein L34 | -0.0185668 |
| NTN4 | netrin 4 | -0.0183246 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0180864 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0178817 |
| RPS3 | ribosomal protein S3 | -0.0177765 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0176203 |
| PIM3 | Pim-3 proto-oncogene, serine/threonine kinase | -0.0174699 |
| POU2F2 | POU class 2 homeobox 2 | -0.0173252 |
| CALR | calreticulin | -0.0172398 |
| ABR | active BCR-related | -0.0171973 |
| RPS24 | ribosomal protein S24 | -0.0169694 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0169645 |
| RPL19 | ribosomal protein L19 | -0.0169403 |
| MCL1 | myeloid cell leukemia 1 | -0.0168931 |
| RPL9 | ribosomal protein L9 | -0.0167165 |
| IL6 | interleukin 6 | -0.0166502 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0166043 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0165454 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0164104 |
| KRT81 | keratin 81, type II | -0.0163459 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0160502 |
| GNAS | GNAS complex locus | -0.0159435 |
| RPS21 | ribosomal protein S21 | -0.0157984 |
| TPM4 | tropomyosin 4 | -0.0156361 |
| RPS6 | ribosomal protein S6 | -0.0155686 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0155454 |
| GJA1 | gap junction protein, alpha 1, 43kDa | -0.0154709 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0153912 |
| ACOXL | acyl-CoA oxidase-like | -0.0153816 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0153627 |
| RPL7A | ribosomal protein L7a | -0.0153374 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0152654 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0148711 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0148538 |
| LAMB3 | laminin, beta 3 | -0.0148086 |
