crotamiton-3388 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the crotamiton-3388 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM8 ADAM metallopeptidase domain 8
AKAP8L A kinase (PRKA) anchor protein 8-like
ANGPTL2 angiopoietin-like 2
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARC activity-regulated cytoskeleton-associated protein
BDKRB2 bradykinin receptor B2
C11ORF16 chromosome 11 open reading frame 16
C17ORF53 chromosome 17 open reading frame 53
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAPN15 calpain 15
CCDC57 coiled-coil domain containing 57
CFAP69 cilia and flagella associated protein 69
CFHR4 complement factor H-related 4
CLTB clathrin, light chain B
COL16A1 collagen, type XVI, alpha 1
COPE coatomer protein complex, subunit epsilon
CPED1 cadherin-like and PC-esterase domain containing 1
CRTC1 CREB regulated transcription coactivator 1
CYLD cylindromatosis (turban tumor syndrome)
DAPK2 death-associated protein kinase 2
DBP D site of albumin promoter (albumin D-box) binding protein
DFNB31 deafness, autosomal recessive 31
DGKG diacylglycerol kinase, gamma 90kDa
EDA ectodysplasin A
EGR3 early growth response 3
EPHB2 EPH receptor B2
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERAP1 endoplasmic reticulum aminopeptidase 1
ERCC2 excision repair cross-complementation group 2
FAXDC2 fatty acid hydroxylase domain containing 2
FBXO21 F-box protein 21
FRS3 fibroblast growth factor receptor substrate 3
FZD10 frizzled class receptor 10
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GPER1 G protein-coupled estrogen receptor 1
GPR3 G protein-coupled receptor 3
GULP1 GULP, engulfment adaptor PTB domain containing 1
HOXC4 homeobox C4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
ICOSLG inducible T-cell co-stimulator ligand
IFI6 interferon, alpha-inducible protein 6
IL11RA interleukin 11 receptor, alpha
IL2RB interleukin 2 receptor, beta
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0368 KIAA0368
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL35 kelch-like family member 35
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
LY6G6C lymphocyte antigen 6 complex, locus G6C
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MEG3 maternally expressed 3 (non-protein coding)
MGAT3 mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
MIER2 mesoderm induction early response 1, family member 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MUC5B mucin 5B, oligomeric mucus/gel-forming
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NDOR1 NADPH dependent diflavin oxidoreductase 1
NF1 neurofibromin 1
NLRP1 NLR family, pyrin domain containing 1
NOP14-AS1 NOP14 antisense RNA 1
NOP16 NOP16 nucleolar protein
NR2E3 nuclear receptor subfamily 2, group E, member 3
NR4A1 nuclear receptor subfamily 4, group A, member 1
NXPH3 neurexophilin 3
PAX8 paired box 8
PDE9A phosphodiesterase 9A
PGR progesterone receptor
PHF20L1 PHD finger protein 20-like 1
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
RAP1GAP RAP1 GTPase activating protein
SAG S-antigen; retina and pineal gland (arrestin)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SH2D3A SH2 domain containing 3A
SIGLEC7 sialic acid binding Ig-like lectin 7
SLAMF8 SLAM family member 8
SMC1A structural maintenance of chromosomes 1A
SOCS1 suppressor of cytokine signaling 1
SPIB Spi-B transcription factor (Spi-1/PU.1 related)
SRRM2 serine/arginine repetitive matrix 2
STS steroid sulfatase (microsomal), isozyme S
SYBU syntabulin (syntaxin-interacting)
TDRD3 tudor domain containing 3
TIMP3 TIMP metallopeptidase inhibitor 3
TJAP1 tight junction associated protein 1 (peripheral)
TMEM246 transmembrane protein 246
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPP1 tripeptidyl peptidase I
VIM vimentin
WNT3 wingless-type MMTV integration site family, member 3
ZDHHC14 zinc finger, DHHC-type containing 14
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF646 zinc finger protein 646
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHNAK2 AHNAK nucleoprotein 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGAP12 Rho GTPase activating protein 12
BRIP1 BRCA1 interacting protein C-terminal helicase 1
BSG basigin (Ok blood group)
C1ORF56 chromosome 1 open reading frame 56
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4ORF29 chromosome 4 open reading frame 29
CAMK4 calcium/calmodulin-dependent protein kinase IV
CCDC132 coiled-coil domain containing 132
CCNK cyclin K
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CLCF1 cardiotrophin-like cytokine factor 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
DMTN dematin actin binding protein
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EFNA1 ephrin-A1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EML4 echinoderm microtubule associated protein like 4
EPHX2 epoxide hydrolase 2, cytoplasmic
ERCC4 excision repair cross-complementation group 4
EXOC5 exocyst complex component 5
FAM53B family with sequence similarity 53, member B
FKBP5 FK506 binding protein 5
GAMT guanidinoacetate N-methyltransferase
GDAP1 ganglioside induced differentiation associated protein 1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLB1L galactosidase, beta 1-like
GPATCH2L G patch domain containing 2-like
GPRIN2 G protein regulated inducer of neurite outgrowth 2
GPX2 glutathione peroxidase 2
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HCAR3 hydroxycarboxylic acid receptor 3
HMOX1 heme oxygenase 1
HP1BP3 heterochromatin protein 1, binding protein 3
INCENP inner centromere protein antigens 135/155kDa
INO80D INO80 complex subunit D
IPO8 importin 8
KIAA0319L KIAA0319-like
KLHL25 kelch-like family member 25
KRT86 keratin 86, type II
LRRC37A3 leucine rich repeat containing 37, member A3
MDM4 MDM4, p53 regulator
METTL16 methyltransferase like 16
MOCS3 molybdenum cofactor synthesis 3
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OSMR oncostatin M receptor
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PRPH peripherin
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
R3HCC1L R3H domain and coiled-coil containing 1-like
RAB27B RAB27B, member RAS oncogene family
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RHBG Rh family, B glycoprotein (gene/pseudogene)
RND1 Rho family GTPase 1
RNF43 ring finger protein 43
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
SCN1B sodium channel, voltage gated, type I beta subunit
SCYL2 SCY1-like 2 (S. cerevisiae)
SH3GLB2 SH3-domain GRB2-like endophilin B2
SLC12A9 solute carrier family 12, member 9
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLPI secretory leukocyte peptidase inhibitor
SP1 Sp1 transcription factor
SYT17 synaptotagmin XVII
SYTL2 synaptotagmin-like 2
TEP1 telomerase-associated protein 1
TET3 tet methylcytosine dioxygenase 3
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TMEM230 transmembrane protein 230
TMEM242 transmembrane protein 242
TMEM53 transmembrane protein 53
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TRIM16 tripartite motif containing 16
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TSPAN1 tetraspanin 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF134 zinc finger protein 134
ZNF230 zinc finger protein 230
ZNF394 zinc finger protein 394
ZNF639 zinc finger protein 639
ZNF652 zinc finger protein 652
ZNF750 zinc finger protein 750