crotamiton-4628 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the crotamiton-4628 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACTA1 actin, alpha 1, skeletal muscle
AGMAT agmatine ureohydrolase (agmatinase)
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
ARHGAP35 Rho GTPase activating protein 35
BCL6 B-cell CLL/lymphoma 6
BEX1 brain expressed, X-linked 1
C1QL1 complement component 1, q subcomponent-like 1
C6ORF10 chromosome 6 open reading frame 10
CAMK4 calcium/calmodulin-dependent protein kinase IV
CDC14A cell division cycle 14A
CLCA2 chloride channel accessory 2
CLMN calmin (calponin-like, transmembrane)
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
DNAAF1 dynein, axonemal, assembly factor 1
DTNA dystrobrevin, alpha
EGFL7 EGF-like-domain, multiple 7
EGR2 early growth response 2
EXO5 exonuclease 5
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM105A family with sequence similarity 105, member A
FAM134B family with sequence similarity 134, member B
FAM163A family with sequence similarity 163, member A
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
GPR22 G protein-coupled receptor 22
GPR50 G protein-coupled receptor 50
GPSM3 G-protein signaling modulator 3
HBE1 hemoglobin, epsilon 1
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4
HFE hemochromatosis
HIC2 hypermethylated in cancer 2
HKDC1 hexokinase domain containing 1
HR hair growth associated
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IBA57 IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
IL11 interleukin 11
IL36G interleukin 36, gamma
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KYNU kynureninase
LCAT lecithin-cholesterol acyltransferase
LIG3 ligase III, DNA, ATP-dependent
LMO7 LIM domain 7
LRRC1 leucine rich repeat containing 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MSC musculin
MYH11 myosin, heavy chain 11, smooth muscle
NF1 neurofibromin 1
NLE1 notchless homolog 1 (Drosophila)
NPR1 natriuretic peptide receptor 1
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
PARP8 poly (ADP-ribose) polymerase family, member 8
PCDHA5 protocadherin alpha 5
PDE11A phosphodiesterase 11A
PDGFA platelet-derived growth factor alpha polypeptide
PKD2L1 polycystic kidney disease 2-like 1
PMFBP1 polyamine modulated factor 1 binding protein 1
POM121 POM121 transmembrane nucleoporin
PPP4R4 protein phosphatase 4, regulatory subunit 4
PRPF31 pre-mRNA processing factor 31
RANBP1 RAN binding protein 1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
SARM1 sterile alpha and TIR motif containing 1
SELL selectin L
SEMG2 semenogelin II
SENP3 SUMO1/sentrin/SMT3 specific peptidase 3
SETD1A SET domain containing 1A
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SHH sonic hedgehog
SIDT2 SID1 transmembrane family, member 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SPEF1 sperm flagellar 1
SPRR1A small proline-rich protein 1A
STAT5B signal transducer and activator of transcription 5B
SYCE1L synaptonemal complex central element protein 1-like
SYCP2 synaptonemal complex protein 2
TGS1 trimethylguanosine synthase 1
TPM3 tropomyosin 3
TSSK2 testis-specific serine kinase 2
TUBGCP2 tubulin, gamma complex associated protein 2
VIPR2 vasoactive intestinal peptide receptor 2
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
VWA5A von Willebrand factor A domain containing 5A
XYLB xylulokinase homolog (H. influenzae)
ZCCHC4 zinc finger, CCHC domain containing 4
ZFPL1 zinc finger protein-like 1
ZNF219 zinc finger protein 219
ZNF280B zinc finger protein 280B
ZNF467 zinc finger protein 467
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ABCB8 ATP-binding cassette, sub-family B (MDR/TAP), member 8
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALS2CL ALS2 C-terminal like
AMT aminomethyltransferase
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
BAG4 BCL2-associated athanogene 4
BTF3P12 basic transcription factor 3 pseudogene 12
C1ORF159 chromosome 1 open reading frame 159
CARD9 caspase recruitment domain family, member 9
CCNO cyclin O
CD72 CD72 molecule
CEP112 centrosomal protein 112kDa
CINP cyclin-dependent kinase 2 interacting protein
CISH cytokine inducible SH2-containing protein
CNR2 cannabinoid receptor 2 (macrophage)
CST1 cystatin SN
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNM3 dynamin 3
DTX2 deltex 2, E3 ubiquitin ligase
ECM1 extracellular matrix protein 1
EHF ets homologous factor
EN1 engrailed homeobox 1
EN2 engrailed homeobox 2
ERAP2 endoplasmic reticulum aminopeptidase 2
FA2H fatty acid 2-hydroxylase
FBRS fibrosin
FGF6 fibroblast growth factor 6
FILIP1L filamin A interacting protein 1-like
FRMPD1 FERM and PDZ domain containing 1
FRS3 fibroblast growth factor receptor substrate 3
FURIN furin (paired basic amino acid cleaving enzyme)
GABARAPL1 GABA(A) receptor-associated protein like 1
GMPR guanosine monophosphate reductase
GRAMD1C GRAM domain containing 1C
HIST1H1D histone cluster 1, H1d
HIST1H2AJ histone cluster 1, H2aj
HIST1H3C histone cluster 1, H3c
HOXA1 homeobox A1
HOXB9 homeobox B9
HRH2 histamine receptor H2
ICOS inducible T-cell co-stimulator
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL11RA interleukin 11 receptor, alpha
IL32 interleukin 32
IQSEC2 IQ motif and Sec7 domain 2
IRF1 interferon regulatory factor 1
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KIAA1456 KIAA1456
KRT31 keratin 31, type I
LHX6 LIM homeobox 6
LY6D lymphocyte antigen 6 complex, locus D
MITF microphthalmia-associated transcription factor
MYLK myosin light chain kinase
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NEUROD1 neuronal differentiation 1
NNAT neuronatin
NR1H4 nuclear receptor subfamily 1, group H, member 4
NSUN6 NOP2/Sun domain family, member 6
NUPR1 nuclear protein, transcriptional regulator, 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PAIP2B poly(A) binding protein interacting protein 2B
PDE12 phosphodiesterase 12
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PLXNB3 plexin B3
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTTG2 pituitary tumor-transforming 2
PWAR5 Prader Willi/Angelman region RNA 5
RAB27B RAB27B, member RAS oncogene family
RIMBP2 RIMS binding protein 2
RUNDC3B RUN domain containing 3B
SARS2 seryl-tRNA synthetase 2, mitochondrial
SCN1B sodium channel, voltage gated, type I beta subunit
SCUBE3 signal peptide, CUB domain, EGF-like 3
SIRT2 sirtuin 2
SLC25A40 solute carrier family 25, member 40
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOX21 SRY (sex determining region Y)-box 21
SOX30 SRY (sex determining region Y)-box 30
SPINK1 serine peptidase inhibitor, Kazal type 1
SYNGR3 synaptogyrin 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM57 transmembrane protein 57
TSPAN2 tetraspanin 2
TXLNG taxilin gamma
USB1 U6 snRNA biogenesis 1
USP27X ubiquitin specific peptidase 27, X-linked
WDR78 WD repeat domain 78
ZNF197 zinc finger protein 197
ZNF208 zinc finger protein 208
ZNF253 zinc finger protein 253
ZNF254 zinc finger protein 254
ZNF286A zinc finger protein 286A
ZNF442 zinc finger protein 442
ZNF747 zinc finger protein 747