crotamiton-5689 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the crotamiton-5689 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
ADGRB3 adhesion G protein-coupled receptor B3
ADGRL3 adhesion G protein-coupled receptor L3
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADORA1 adenosine A1 receptor
ADRA1B adrenoceptor alpha 1B
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AMBP alpha-1-microglobulin/bikunin precursor
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APCS amyloid P component, serum
ATG10 autophagy related 10
C5AR1 complement component 5a receptor 1
CCDC28B coiled-coil domain containing 28B
CCDC40 coiled-coil domain containing 40
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CD22 CD22 molecule
CD80 CD80 molecule
CD8A CD8a molecule
CDHR1 cadherin-related family member 1
COL10A1 collagen, type X, alpha 1
CYP11B1 cytochrome P450, family 11, subfamily B, polypeptide 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DLX4 distal-less homeobox 4
DMWD dystrophia myotonica, WD repeat containing
DPP6 dipeptidyl-peptidase 6
EPHA5 EPH receptor A5
EPN1 epsin 1
FAM63B family with sequence similarity 63, member B
FGR FGR proto-oncogene, Src family tyrosine kinase
FOXN3 forkhead box N3
FST follistatin
FZD10 frizzled class receptor 10
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GADD45G growth arrest and DNA-damage-inducible, gamma
GIMAP5 GTPase, IMAP family member 5
GIMAP6 GTPase, IMAP family member 6
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
HFE hemochromatosis
HIST1H1E histone cluster 1, H1e
HIST1H2BN histone cluster 1, H2bn
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXA9 homeobox A9
HOXC5 homeobox C5
HP haptoglobin
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIR2DL3 killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 3
KLRF1 killer cell lectin-like receptor subfamily F, member 1
KRT83 keratin 83, type II
LIMD1 LIM domains containing 1
LIMK2 LIM domain kinase 2
LINC00260 long intergenic non-protein coding RNA 260
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MEG3 maternally expressed 3 (non-protein coding)
METTL7A methyltransferase like 7A
MOCS1 molybdenum cofactor synthesis 1
MR1 major histocompatibility complex, class I-related
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCAM1 neural cell adhesion molecule 1
NDRG2 NDRG family member 2
OBSCN obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
PCDH1 protocadherin 1
PCSK2 proprotein convertase subtilisin/kexin type 2
PDE4DIP phosphodiesterase 4D interacting protein
PPP1R17 protein phosphatase 1, regulatory subunit 17
PRRG3 proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
RB1 retinoblastoma 1
RGS6 regulator of G-protein signaling 6
RIN1 Ras and Rab interactor 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SIPA1 signal-induced proliferation-associated 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1
SMAD9 SMAD family member 9
SMR3A submaxillary gland androgen regulated protein 3A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SORBS1 sorbin and SH3 domain containing 1
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
SRSF7 serine/arginine-rich splicing factor 7
STS steroid sulfatase (microsomal), isozyme S
SYP synaptophysin
TAS2R1 taste receptor, type 2, member 1
TBX6 T-box 6
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TRHDE thyrotropin-releasing hormone degrading enzyme
TUBA4B tubulin, alpha 4b
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
ZBTB18 zinc finger and BTB domain containing 18
ZNF287 zinc finger protein 287
ZNF518A zinc finger protein 518A

decreased expression

Symbol Name
ABHD14A abhydrolase domain containing 14A
ACTL8 actin-like 8
ADCY6 adenylate cyclase 6
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APH1A APH1A gamma secretase subunit
APLP1 amyloid beta (A4) precursor-like protein 1
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BAX BCL2-associated X protein
C11ORF95 chromosome 11 open reading frame 95
C16ORF45 chromosome 16 open reading frame 45
C6ORF47 chromosome 6 open reading frame 47
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CORT cortistatin
CRABP1 cellular retinoic acid binding protein 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
ECI1 enoyl-CoA delta isomerase 1
EFNA3 ephrin-A3
ERCC4 excision repair cross-complementation group 4
FAM131A family with sequence similarity 131, member A
FAM169A family with sequence similarity 169, member A
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FKBP10 FK506 binding protein 10, 65 kDa
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GALK1 galactokinase 1
GPATCH2L G patch domain containing 2-like
GPX2 glutathione peroxidase 2
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2BC histone cluster 1, H2bc
HIST1H3B histone cluster 1, H3b
HPN hepsin
HSPA2 heat shock 70kDa protein 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IFT140 intraflagellar transport 140
IKZF5 IKAROS family zinc finger 5 (Pegasus)
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KCTD20 potassium channel tetramerization domain containing 20
KLF2 Kruppel-like factor 2
KLF7 Kruppel-like factor 7 (ubiquitous)
KRT13 keratin 13, type I
LMNB1 lamin B1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
MDM4 MDM4, p53 regulator
MICALL2 MICAL-like 2
MOGS mannosyl-oligosaccharide glucosidase
MORC3 MORC family CW-type zinc finger 3
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MVD mevalonate (diphospho) decarboxylase
NAG18 NAG18 mRNA
NDRG1 N-myc downstream regulated 1
NEK11 NIMA-related kinase 11
NES nestin
NPM3 nucleophosmin/nucleoplasmin 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OVGP1 oviductal glycoprotein 1, 120kDa
PCDHB3 protocadherin beta 3
PITX2 paired-like homeodomain 2
PODNL1 podocan-like 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
POLL polymerase (DNA directed), lambda
POM121 POM121 transmembrane nucleoporin
PPAP2C phosphatidic acid phosphatase type 2C
PRR7 proline rich 7 (synaptic)
RFTN1 raftlin, lipid raft linker 1
RPGRIP1L RPGRIP1-like
RPH3AL rabphilin 3A-like (without C2 domains)
RPL13P5 ribosomal protein L13 pseudogene 5
S100A4 S100 calcium binding protein A4
S100A9 S100 calcium binding protein A9
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLMO1 slowmo homolog 1 (Drosophila)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STARD5 StAR-related lipid transfer (START) domain containing 5
STIM1 stromal interaction molecule 1
STX5 syntaxin 5
SYT17 synaptotagmin XVII
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBC1D17 TBC1 domain family, member 17
TRABD TraB domain containing
TRIM25 tripartite motif containing 25
TRIP10 thyroid hormone receptor interactor 10
WLS wntless Wnt ligand secretion mediator
YEATS2 YEATS domain containing 2
ZBTB6 zinc finger and BTB domain containing 6
ZC3H3 zinc finger CCCH-type containing 3
ZMAT5 zinc finger, matrin-type 5
ZNF254 zinc finger protein 254
ZNF428 zinc finger protein 428
ZNF573 zinc finger protein 573
ZNRD1-AS1 ZNRD1 antisense RNA 1