crouzon syndrome Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A craniosynostosis that involves premature fusion of certain skull bones. This early fusion prevents the skull from growing normally and affects the shape of the head and face. The disease is associated with mutations in the FGFR2 gene. (Human Disease Ontology, DOID_2339)
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Genes

40 genes co-occuring with the disease crouzon syndrome in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
FGFR2 fibroblast growth factor receptor 2 2.83474
FGFR3 fibroblast growth factor receptor 3 2.03471
FGFR1 fibroblast growth factor receptor 1 1.5423
FGF1 fibroblast growth factor 1 (acidic) 1.29571
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 1.06186
IL11RA interleukin 11 receptor, alpha 0.933727
PYGO2 pygopus family PHD finger 2 0.886389
STRC stereocilin 0.863046
STRCP1 stereocilin pseudogene 1 0.863046
BGN biglycan 0.814283
FGF10 fibroblast growth factor 10 0.767167
MSX2 msh homeobox 2 0.74436
VPREB1 pre-B lymphocyte 1 0.693098
FGF4 fibroblast growth factor 4 0.639463
HOPX HOP homeobox 0.608104
RUNX2 runt-related transcription factor 2 0.597961
FMN1 formin 1 0.528835
FGF7 fibroblast growth factor 7 0.527676
FRS2 fibroblast growth factor receptor substrate 2 0.517265
DCN decorin 0.491215
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.489691
GRB2 growth factor receptor-bound protein 2 0.465038
FGF2 fibroblast growth factor 2 (basic) 0.457864
FGR FGR proto-oncogene, Src family tyrosine kinase 0.431144
FN1 fibronectin 1 0.402318
NEFM neurofilament, medium polypeptide 0.401945
FGF8 fibroblast growth factor 8 (androgen-induced) 0.351187
LOR loricrin 0.346777
CKM creatine kinase, muscle 0.320817
GYPE glycophorin E (MNS blood group) 0.306672
IHH indian hedgehog 0.290821
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.287952
ALPPL2 alkaline phosphatase, placental-like 2 0.260184
ALPP alkaline phosphatase, placental 0.25983
ALPL alkaline phosphatase, liver/bone/kidney 0.259477
TWIST1 twist family bHLH transcription factor 1 0.226262
PGRMC1 progesterone receptor membrane component 1 0.19582
TGFB3 transforming growth factor, beta 3 0.187415
IRF6 interferon regulatory factor 6 0.175146
COL2A1 collagen, type II, alpha 1 0.174617