crx Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description cone-rod homeobox|The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 1406)
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Genes

13 genes co-occuring with the biological term crx in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
BEST1 bestrophin 1
CRX cone-rod homeobox
FIZ1 FLT3-interacting zinc finger 1
NEUROD1 neuronal differentiation 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRL neural retina leucine zipper
NXNL1 nucleoredoxin-like 1
NXNL2 nucleoredoxin-like 2
OTX1 orthodenticle homeobox 1
OTX2 orthodenticle homeobox 2
PDE6A phosphodiesterase 6A, cGMP-specific, rod, alpha
RAX retina and anterior neural fold homeobox
SAMD11 sterile alpha motif domain containing 11