cryoglobulinemia Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A condition characterized by the presence of cryoglobulins in the blood. Cryoglobulins are abnormal proteins that precipitate within the microvasculature on exposure to cold; microvasculature effects of cryoglobulinemia may result in restricted tissue blood flow, tissue hypoxia, and tissue necrosis. --2004 (Experimental Factor Ontology, EFO_0005846)
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Genes

115 genes co-occuring with the disease cryoglobulinemia in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD79A CD79a molecule, immunoglobulin-associated alpha 1.60368
CD81 CD81 molecule 1.44035
IFNA1 interferon, alpha 1 1.43113
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene 1.22779
TSLP thymic stromal lymphopoietin 1.20223
CD5 CD5 molecule 1.1507
CXCL10 chemokine (C-X-C motif) ligand 10 1.103
CD27 CD27 molecule 1.08957
IFNA2 interferon, alpha 2 1.06984
IGKV3-20 immunoglobulin kappa variable 3-20 1.00288
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b 0.918436
FCRLA Fc receptor-like A 0.852811
GALK2 galactokinase 2 0.833558
FN1 fibronectin 1 0.829869
ALB albumin 0.826999
SPPL2A signal peptide peptidase like 2A 0.814693
TRIM21 tripartite motif containing 21 0.807718
FCRL5 Fc receptor-like 5 0.798692
C3 complement component 3 0.798282
CXCR3 chemokine (C-X-C motif) receptor 3 0.795411
CXCL11 chemokine (C-X-C motif) ligand 11 0.791721
RAF1 Raf-1 proto-oncogene, serine/threonine kinase 0.767167
SOS1 son of sevenless homolog 1 (Drosophila) 0.728547
CD4 CD4 molecule 0.70434
IGHV3-9 immunoglobulin heavy variable 3-9 0.681894
PIGM phosphatidylinositol glycan anchor biosynthesis, class M 0.656441
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.637102
KRAS Kirsten rat sarcoma viral oncogene homolog 0.633563
MT1H metallothionein 1H 0.632777
CD19 CD19 molecule 0.60108
PRTN3 proteinase 3 0.589779
SH2D1A SH2 domain containing 1A 0.581217
MAGEE1 melanoma antigen family E1 0.568775
FCRL4 Fc receptor-like 4 0.567609
APOH apolipoprotein H (beta-2-glycoprotein I) 0.545868
IFNE interferon, epsilon 0.545093
IGLV7-43 immunoglobulin lambda variable 7-43 0.536957
CLTC clathrin, heavy chain (Hc) 0.532314
CXCL9 chemokine (C-X-C motif) ligand 9 0.516494
TECR trans-2,3-enoyl-CoA reductase 0.510344
MCAT malonyl CoA:ACP acyltransferase (mitochondrial) 0.494648
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.481705
SLC28A1 solute carrier family 28 (concentrative nucleoside transporter), member 1 0.47753
BHLHE40 basic helix-loop-helix family, member e40 0.441666
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.437154
MIRLET7D microRNA let-7d 0.435651
IL31RA interleukin 31 receptor A 0.431144
HLA-DQB3 major histocompatibility complex, class II, DQ beta 3 0.430768
FCGR2B Fc fragment of IgG, low affinity IIb, receptor (CD32) 0.42589
MIR26B microRNA 26b 0.421765
PIDD1 p53-induced death domain protein 1 0.418019
SOX5 SRY (sex determining region Y)-box 5 0.397471
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.397471
ACTA1 actin, alpha 1, skeletal muscle 0.397098
MALT1 MALT1 paracaspase 0.394863
PIGN phosphatidylinositol glycan anchor biosynthesis, class N 0.394118
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 0.367779
MYRF myelin regulatory factor 0.354868
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.338341
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.333949
CXCL13 chemokine (C-X-C motif) ligand 13 0.332121
ENO1 enolase 1, (alpha) 0.32993
CFP complement factor properdin 0.322637
BCR breakpoint cluster region 0.32009
LYZ lysozyme 0.318635
CAND2 cullin-associated and neddylation-dissociated 2 (putative) 0.318272
TNF tumor necrosis factor 0.317545
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.311739
HIST1H2AJ histone cluster 1, H2aj 0.309566
HIST1H2AD histone cluster 1, H2ad 0.309566
C5AR1 complement component 5a receptor 1 0.30848
H2AFV H2A histone family, member V 0.307757
H2AFB2 H2A histone family, member B2 0.307395
H2AFY2 H2A histone family, member Y2 0.305948
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 0.305948
H2AFB1 H2A histone family, member B1 0.305948
LCK LCK proto-oncogene, Src family tyrosine kinase 0.305226
H2AFJ H2A histone family, member J 0.305226
HIST1H2AH histone cluster 1, H2ah 0.305226
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.302337
HIST1H2AM histone cluster 1, H2am 0.301615
HM13 histocompatibility (minor) 13 0.299452
HIST1H2AE histone cluster 1, H2ae 0.296571
HIST1H2AB histone cluster 1, H2ab 0.296571
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.293694
IFNL3 interferon, lambda 3 0.292616
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.292616
CRP C-reactive protein, pentraxin-related 0.291539
HIST1H2AG histone cluster 1, H2ag 0.289744
TLR9 toll-like receptor 9 0.282225
MAG myelin associated glycoprotein 0.275089
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.272597
FCGR3B Fc fragment of IgG, low affinity IIIb, receptor (CD16b) 0.272597
H2AFY H2A histone family, member Y 0.266203
LAG3 lymphocyte-activation gene 3 0.258064
BIRC3 baculoviral IAP repeat containing 3 0.254536
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.251015
PDGFA platelet-derived growth factor alpha polypeptide 0.235616
MRI1 methylthioribose-1-phosphate isomerase 1 0.234225
WDR11 WD repeat domain 11 0.231795
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.231102
HBE1 hemoglobin, epsilon 1 0.225573
F12 coagulation factor XII (Hageman factor) 0.224884
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.224196
CFI complement factor I 0.221108
BTNL2 butyrophilin-like 2 0.220766
FGR FGR proto-oncogene, Src family tyrosine kinase 0.200982
TROVE2 TROVE domain family, member 2 0.184128
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.182086
IFNB1 interferon, beta 1, fibroblast 0.171286
GGT1 gamma-glutamyltransferase 1 0.167452
CD86 CD86 molecule 0.165217
HLA-C major histocompatibility complex, class I, C 0.163111
PORCN porcupine homolog (Drosophila) 0.161139
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.160203