cryptorchidism Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description Cryptorchidism (derived from the Greek κρυπτός, kryptos, meaning hidden and ὄρχις, orchis, meaning testicle) is the absence of one or both testes from the scrotum. It is the most common birth defect regarding male genitalia. In unique cases, cryptorchidism can develop later in life, often as late as young adulthood. About 3% of full-term and 30% of premature infant boys are born with at least one undescended testis. However, about 80% of cryptorchid testes descend by the first year of life (the majority within three months), making the true incidence of cryptorchidism around 1% overall. Cryptorchidism is distinct from monorchism the condition of having only one testicle. (Experimental Factor Ontology, EFO_0004562)
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Genes

18 genes co-occuring with the biological term cryptorchidism in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AMH anti-Mullerian hormone
ANOS1 anosmin 1
AR androgen receptor
AZF1 azoospermia factor 1
DAZ1 deleted in azoospermia 1
DEL9P Chromosome 9p deletion syndrome
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FGFR1 fibroblast growth factor receptor 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
INSL3 insulin-like 3 (Leydig cell)
NR5A1 nuclear receptor subfamily 5, group A, member 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RXFP2 relaxin/insulin-like family peptide receptor 2
SOS1 son of sevenless homolog 1 (Drosophila)
SPAG5 sperm associated antigen 5
STRBP spermatid perinuclear RNA binding protein