curcumin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A beta-diketone that is methane in which two of the hydrogens are substituted by feruloyl groups. A natural dyestuff found in the root of Curcuma longa. (Chemical Entities of Biological Interest Ontology, CHEBI_3962)
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Genes

90 genes co-occuring with the biological term curcumin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
AHR aryl hydrocarbon receptor
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
AKT1 v-akt murine thymoma viral oncogene homolog 1
APAF1 apoptotic peptidase activating factor 1
APOE apolipoprotein E
APP amyloid beta (A4) precursor protein
ARNT aryl hydrocarbon receptor nuclear translocator
BAX BCL2-associated X protein
CAMP cathelicidin antimicrobial peptide
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CDA cytidine deaminase
CDC42 cell division cycle 42
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CTTN cortactin
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DDIT3 DNA-damage-inducible transcript 3
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DUSP10 dual specificity phosphatase 10
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
ELK1 ELK1, member of ETS oncogene family
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC8 histone deacetylase 8
HMOX1 heme oxygenase 1
ICAM1 intercellular adhesion molecule 1
IFNA1 interferon, alpha 1
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL6 interleukin 6
ITGA6 integrin, alpha 6
ITGB4 integrin, beta 4
IVL involucrin
JAK2 Janus kinase 2
LOX lysyl oxidase
MAPK14 mitogen-activated protein kinase 14
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MIR200A microRNA 200a
MIR200B microRNA 200b
MIR21 microRNA 21
MIR7-1 microRNA 7-1
MIR7-2 microRNA 7-2
MIR7-3 microRNA 7-3
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NAMPT nicotinamide phosphoribosyltransferase
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase)
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOD2 nucleotide-binding oligomerization domain containing 2
NOTCH1 notch 1
PLAU plasminogen activator, urokinase
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RAD51 RAD51 recombinase
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOCS1 suppressor of cytokine signaling 1
SOCS3 suppressor of cytokine signaling 3
SP1 Sp1 transcription factor
SP3 Sp3 transcription factor
SP4 Sp4 transcription factor
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SREBF1 sterol regulatory element binding transcription factor 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TP53 tumor protein p53
TXNRD1 thioredoxin reductase 1
VCAM1 vascular cell adhesion molecule 1
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
WT1 Wilms tumor 1
ZBTB7A zinc finger and BTB domain containing 7A