cutaneous leishmaniasis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A leishmaniasis that involves skin infection caused by Leishmania species, resulting in one or more cutaneous lesions. (Human Disease Ontology, DOID_9111)
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Genes

129 genes co-occuring with the disease cutaneous leishmaniasis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
CD4 CD4 molecule 1.71134
LONP1 lon peptidase 1, mitochondrial 1.68997
PGD phosphogluconate dehydrogenase 1.56489
IL4 interleukin 4 1.36727
NELFCD negative elongation factor complex member C/D 1.35158
IL10 interleukin 10 1.16692
PKD2L1 polycystic kidney disease 2-like 1 1.11057
GPI glucose-6-phosphate isomerase 1.08999
TNF tumor necrosis factor 1.0711
MON2 MON2 homolog (S. cerevisiae) 1.03072
FOXP3 forkhead box P3 0.957033
RRAGC Ras-related GTP binding C 0.879014
G6PD glucose-6-phosphate dehydrogenase 0.869187
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.852402
WDR83 WD repeat domain 83 0.817155
GSX2 GS homeobox 2 0.800333
TLR9 toll-like receptor 9 0.790902
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) 0.783526
TLR4 toll-like receptor 4 0.77575
TLR2 toll-like receptor 2 0.774523
IFNG interferon, gamma 0.770844
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 0.769618
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.762271
GSX1 GS homeobox 1 0.722482
IL2 interleukin 2 0.712796
CCL3 chemokine (C-C motif) ligand 3 0.692697
CXCL10 chemokine (C-X-C motif) ligand 10 0.6791
CD40 CD40 molecule, TNF receptor superfamily member 5 0.674315
DDX24 DEAD (Asp-Glu-Ala-Asp) box helicase 24 0.673518
NT5C 5', 3'-nucleotidase, cytosolic 0.669538
CCL2 chemokine (C-C motif) ligand 2 0.646953
CCR7 chemokine (C-C motif) receptor 7 0.627672
STAT4 signal transducer and activator of transcription 4 0.615529
CD86 CD86 molecule 0.604201
LMTK2 lemur tyrosine kinase 2 0.60225
RHOQ ras homolog family member Q 0.60069
TGFB1 transforming growth factor, beta 1 0.597571
LTA lymphotoxin alpha 0.594454
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) 0.586665
APOE apolipoprotein E 0.579661
GALP galanin-like peptide 0.575772
TSPO translocator protein (18kDa) 0.556732
IL1B interleukin 1, beta 0.556344
LMLN leishmanolysin-like (metallopeptidase M8 family) 0.556344
CD69 CD69 molecule 0.540055
CD209 CD209 molecule 0.535022
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.531541
TLR7 toll-like receptor 7 0.506123
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.502675
FASLG Fas ligand (TNF superfamily, member 6) 0.497703
LHCGR luteinizing hormone/choriogonadotropin receptor 0.490072
EML1 echinoderm microtubule associated protein like 1 0.489691
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.473361
CD68 CD68 molecule 0.469197
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.450701
CLEC4M C-type lectin domain family 4, member M 0.447687
CD79A CD79a molecule, immunoglobulin-associated alpha 0.437154
SERPINH1 serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) 0.434524
ARG1 arginase 1 0.433772
CCL8 chemokine (C-C motif) ligand 8 0.432646
SOCS1 suppressor of cytokine signaling 1 0.427015
CXCR3 chemokine (C-X-C motif) receptor 3 0.42139
PEPD peptidase D 0.415024
IRF1 interferon regulatory factor 1 0.412779
IL1A interleukin 1, alpha 0.411657
CCL7 chemokine (C-C motif) ligand 7 0.402692
ICAM1 intercellular adhesion molecule 1 0.397843
CCL4 chemokine (C-C motif) ligand 4 0.391141
CD80 CD80 molecule 0.390397
UCN2 urocortin 2 0.381481
PGLYRP1 peptidoglycan recognition protein 1 0.376661
TCHH trichohyalin 0.37555
TAS1R1 taste receptor, type 1, member 1 0.371107
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.364085
NOS2 nitric oxide synthase 2, inducible 0.360026
IL5 interleukin 5 0.357814
LYZ lysozyme 0.351187
ICAM3 intercellular adhesion molecule 3 0.348614
VIP vasoactive intestinal peptide 0.347879
CD83 CD83 molecule 0.337975
IL13 interleukin 13 0.333583
CD244 CD244 molecule, natural killer cell receptor 2B4 0.333218
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 0.332852
ESPN espin 0.32993
CXCL2 chemokine (C-X-C motif) ligand 2 0.316819
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.315729
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.311014
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.300533
PRKCZ protein kinase C, zeta 0.296211
ACAP3 ArfGAP with coiled-coil, ankyrin repeat and PH domains 3 0.294772
LTB lymphotoxin beta (TNF superfamily, member 3) 0.291539
CD1B CD1b molecule 0.287235
CXCL9 chemokine (C-X-C motif) ligand 9 0.286877
MT2A metallothionein 2A 0.283297
CXCL3 chemokine (C-X-C motif) ligand 3 0.279011
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta 0.266913
CFAP74 cilia and flagella associated protein 74 0.264431
THEM5 thioesterase superfamily member 5 0.261599
ANXA5 annexin A5 0.252422
TMPO thymopoietin 0.248203
TREH trehalase (brush-border membrane glycoprotein) 0.246448
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.242245
IL2RA interleukin 2 receptor, alpha 0.238054
NPS neuropeptide S 0.232489
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.230755
CTSL cathepsin L 0.218374
CCL11 chemokine (C-C motif) ligand 11 0.217693
MGAM maltase-glucoamylase 0.216672
KRT4 keratin 4, type II 0.212271
GPT glutamic-pyruvate transaminase (alanine aminotransferase) 0.211597
IL3 interleukin 3 0.211261
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 0.210589
PNP purine nucleoside phosphorylase 0.208245
RORC RAR-related orphan receptor C 0.200006
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.195501
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.188022
NPY neuropeptide Y 0.187415
CD276 CD276 molecule 0.18651
TAC1 tachykinin, precursor 1 0.180937
FDFT1 farnesyl-diphosphate farnesyltransferase 1 0.174354
CCL17 chemokine (C-C motif) ligand 17 0.173571
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.170544
ACOT7 acyl-CoA thioesterase 7 0.170054
DHODH dihydroorotate dehydrogenase (quinone) 0.16933
CCL4L2 chemokine (C-C motif) ligand 4-like 2 0.167682
IPP intracisternal A particle-promoted polypeptide 0.167452
TBX21 T-box 21 0.165435
PIDD1 p53-induced death domain protein 1 0.164359
CCL4L1 chemokine (C-C motif) ligand 4-like 1 0.163523