cxcl8 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description chemokine (C-X-C motif) ligand 8|The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3576)
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Genes

86 genes co-occuring with the biological term cxcl8 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACKR3 atypical chemokine receptor 3
ADAM12 ADAM metallopeptidase domain 12
ADIPOQ adiponectin, C1Q and collagen domain containing
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANPEP alanyl (membrane) aminopeptidase
ARNT aryl hydrocarbon receptor nuclear translocator
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTC betacellulin
CCL17 chemokine (C-C motif) ligand 17
CCL2 chemokine (C-C motif) ligand 2
CCL20 chemokine (C-C motif) ligand 20
CCL27 chemokine (C-C motif) ligand 27
CCL4 chemokine (C-C motif) ligand 4
CCL5 chemokine (C-C motif) ligand 5
CCL7 chemokine (C-C motif) ligand 7
CCR1 chemokine (C-C motif) receptor 1
CD14 CD14 molecule
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL2 chemokine (C-X-C motif) ligand 2
CXCL3 chemokine (C-X-C motif) ligand 3
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
DDT D-dopachrome tautomerase
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DOCK2 dedicator of cytokinesis 2
EGF epidermal growth factor
EGFR epidermal growth factor receptor
HBEGF heparin-binding EGF-like growth factor
IFNG interferon, gamma
IL17A interleukin 17A
IL17F interleukin 17F
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JUN jun proto-oncogene
LIF leukemia inhibitory factor
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MYD88 myeloid differentiation primary response 88
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOX1 NADPH oxidase 1
PADI1 peptidyl arginine deiminase, type I
PTEN phosphatase and tensin homolog
PTGFR prostaglandin F receptor (FP)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PXN paxillin
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
RCAN1 regulator of calcineurin 1
RCAN2 regulator of calcineurin 2
RCAN3 RCAN family member 3
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
S100A9 S100 calcium binding protein A9
SDC3 syndecan 3
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TLR2 toll-like receptor 2
TLR3 toll-like receptor 3
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSLP thymic stromal lymphopoietin
VEGFA vascular endothelial growth factor A
ZFP36 ZFP36 ring finger protein