cxcr1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description chemokine (C-X-C motif) receptor 1|The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3577)
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Genes

25 genes co-occuring with the biological term cxcr1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BCL2 B-cell CLL/lymphoma 2
BIRC5 baculoviral IAP repeat containing 5
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCR2 chemokine (C-C motif) receptor 2
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CX3CR1 chemokine (C-X3-C motif) receptor 1
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR1 chemokine (C-X-C motif) receptor 1
CXCR2 chemokine (C-X-C motif) receptor 2
CXCR3 chemokine (C-X-C motif) receptor 3
CXCR4 chemokine (C-X-C motif) receptor 4
ELANE elastase, neutrophil expressed
F2RL1 coagulation factor II (thrombin) receptor-like 1
ICAM1 intercellular adhesion molecule 1
IL2 interleukin 2
IL22 interleukin 22
IL6 interleukin 6
MMP9 matrix metallopeptidase 9
PTEN phosphatase and tensin homolog
PXN paxillin
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1