cyanocobalamin-3252 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

194 genes differentially expressed following the cyanocobalamin-3252 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACVR1B activin A receptor, type IB
ADAM22 ADAM metallopeptidase domain 22
AKAP13 A kinase (PRKA) anchor protein 13
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
ARHGAP4 Rho GTPase activating protein 4
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
BCL7A B-cell CLL/lymphoma 7A
BIN1 bridging integrator 1
C11ORF63 chromosome 11 open reading frame 63
C2ORF54 chromosome 2 open reading frame 54
CA12 carbonic anhydrase XII
CA5B carbonic anhydrase VB, mitochondrial
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK1D calcium/calmodulin-dependent protein kinase ID
CDK10 cyclin-dependent kinase 10
CDK20 cyclin-dependent kinase 20
CFAP45 cilia and flagella associated protein 45
CIC capicua transcriptional repressor
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CORO7 coronin 7
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CUL7 cullin 7
CYLD cylindromatosis (turban tumor syndrome)
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EPHX2 epoxide hydrolase 2, cytoplasmic
FGFR4 fibroblast growth factor receptor 4
FH fumarate hydratase
FKBP10 FK506 binding protein 10, 65 kDa
FLT4 fms-related tyrosine kinase 4
FOSL2 FOS-like antigen 2
GATAD1 GATA zinc finger domain containing 1
GPATCH3 G patch domain containing 3
GPR137 G protein-coupled receptor 137
H1F0 H1 histone family, member 0
H1FX H1 histone family, member X
HIC2 hypermethylated in cancer 2
HLA-G major histocompatibility complex, class I, G
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IL5RA interleukin 5 receptor, alpha
KHSRP KH-type splicing regulatory protein
KIAA0319L KIAA0319-like
KLHL25 kelch-like family member 25
KRT8 keratin 8, type II
LOC157562 uncharacterized LOC157562
MDM4 MDM4, p53 regulator
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MUC1 mucin 1, cell surface associated
MUC3A mucin 3A, cell surface associated
NBL1 neuroblastoma 1, DAN family BMP antagonist
NFIB nuclear factor I/B
NPM3 nucleophosmin/nucleoplasmin 3
NT5M 5',3'-nucleotidase, mitochondrial
PAIP2B poly(A) binding protein interacting protein 2B
PALM paralemmin
PARP16 poly (ADP-ribose) polymerase family, member 16
PAX8 paired box 8
PBX2 pre-B-cell leukemia homeobox 2
PCDHB3 protocadherin beta 3
PENK proenkephalin
PHF1 PHD finger protein 1
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLCG1 phospholipase C, gamma 1
POLQ polymerase (DNA directed), theta
PRDM16 PR domain containing 16
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RGCC regulator of cell cycle
RIN2 Ras and Rab interactor 2
RNF208 ring finger protein 208
SETD1B SET domain containing 1B
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SIK3 SIK family kinase 3
SIM2 single-minded family bHLH transcription factor 2
SLC22A14 solute carrier family 22, member 14
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16
SLC35E2 solute carrier family 35, member E2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRRM2 serine/arginine repetitive matrix 2
STX1A syntaxin 1A (brain)
SUGP1 SURP and G patch domain containing 1
TDRD3 tudor domain containing 3
THOP1 thimet oligopeptidase 1
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast)
TP53I11 tumor protein p53 inducible protein 11
TRAK1 trafficking protein, kinesin binding 1
TSC22D4 TSC22 domain family, member 4
TSPYL2 TSPY-like 2
U2AF2 U2 small nuclear RNA auxiliary factor 2
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
YPEL1 yippee-like 1 (Drosophila)
YRDC yrdC N(6)-threonylcarbamoyltransferase domain containing
YY2 YY2 transcription factor
ZNF224 zinc finger protein 224
ZNF236 zinc finger protein 236
ZNF862 zinc finger protein 862

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ADGRG2 adhesion G protein-coupled receptor G2
ADM adrenomedullin
APLP1 amyloid beta (A4) precursor-like protein 1
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARMC4 armadillo repeat containing 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C19ORF40 chromosome 19 open reading frame 40
C1QTNF3 C1q and tumor necrosis factor related protein 3
C4ORF29 chromosome 4 open reading frame 29
C5AR2 complement component 5a receptor 2
CA5BP1 carbonic anhydrase VB pseudogene 1
CCNT1 cyclin T1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CGREF1 cell growth regulator with EF-hand domain 1
CLCN6 chloride channel, voltage-sensitive 6
CLSPN claspin
CSF1R colony stimulating factor 1 receptor
DCAF13 DDB1 and CUL4 associated factor 13
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
DMC1 DNA meiotic recombinase 1
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
EXO5 exonuclease 5
FADS2 fatty acid desaturase 2
FAM188A family with sequence similarity 188, member A
FBXW12 F-box and WD repeat domain containing 12
FUZ fuzzy planar cell polarity protein
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GNL1 guanine nucleotide binding protein-like 1
GPATCH2L G patch domain containing 2-like
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
GUSBP3 glucuronidase, beta pseudogene 3
HELLS helicase, lymphoid-specific
HIST1H1D histone cluster 1, H1d
HIST1H4A histone cluster 1, H4a
HIST1H4F histone cluster 1, H4f
HPN hepsin
IPP intracisternal A particle-promoted polypeptide
KIAA0894 KIAA0894 protein
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
MAPKBP1 mitogen-activated protein kinase binding protein 1
MATK megakaryocyte-associated tyrosine kinase
MBTD1 mbt domain containing 1
MIS18BP1 MIS18 binding protein 1
MITF microphthalmia-associated transcription factor
MPHOSPH8 M-phase phosphoprotein 8
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OVOL1 ovo-like zinc finger 1
PCDHA9 protocadherin alpha 9
PGBD5 piggyBac transposable element derived 5
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POM121 POM121 transmembrane nucleoporin
PRAMEF11 PRAME family member 11
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RPL23AP32 ribosomal protein L23a pseudogene 32
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPRYD7 SPRY domain containing 7
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
STAG3L4 stromal antigen 3-like 4 (pseudogene)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAOK1 TAO kinase 1
TBC1D17 TBC1 domain family, member 17
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM184C transmembrane protein 184C
TMEM209 transmembrane protein 209
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
UBQLN4 ubiquilin 4
USP36 ubiquitin specific peptidase 36
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WFDC2 WAP four-disulfide core domain 2
WLS wntless Wnt ligand secretion mediator
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF219 zinc finger protein 219
ZNF652 zinc finger protein 652
ZNF721 zinc finger protein 721
ZNF816 zinc finger protein 816