| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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194 genes differentially expressed following the cyanocobalamin-3252 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| ARHGAP4 | Rho GTPase activating protein 4 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| BCL7A | B-cell CLL/lymphoma 7A |
| BIN1 | bridging integrator 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CA12 | carbonic anhydrase XII |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CDK10 | cyclin-dependent kinase 10 |
| CDK20 | cyclin-dependent kinase 20 |
| CFAP45 | cilia and flagella associated protein 45 |
| CIC | capicua transcriptional repressor |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 |
| CORO7 | coronin 7 |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CUL7 | cullin 7 |
| CYLD | cylindromatosis (turban tumor syndrome) |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EPHX2 | epoxide hydrolase 2, cytoplasmic |
| FGFR4 | fibroblast growth factor receptor 4 |
| FH | fumarate hydratase |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FLT4 | fms-related tyrosine kinase 4 |
| FOSL2 | FOS-like antigen 2 |
| GATAD1 | GATA zinc finger domain containing 1 |
| GPATCH3 | G patch domain containing 3 |
| GPR137 | G protein-coupled receptor 137 |
| H1F0 | H1 histone family, member 0 |
| H1FX | H1 histone family, member X |
| HIC2 | hypermethylated in cancer 2 |
| HLA-G | major histocompatibility complex, class I, G |
| HTATIP2 | HIV-1 Tat interactive protein 2, 30kDa |
| IL5RA | interleukin 5 receptor, alpha |
| KHSRP | KH-type splicing regulatory protein |
| KIAA0319L | KIAA0319-like |
| KLHL25 | kelch-like family member 25 |
| KRT8 | keratin 8, type II |
| LOC157562 | uncharacterized LOC157562 |
| MDM4 | MDM4, p53 regulator |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MS4A1 | membrane-spanning 4-domains, subfamily A, member 1 |
| MUC1 | mucin 1, cell surface associated |
| MUC3A | mucin 3A, cell surface associated |
| NBL1 | neuroblastoma 1, DAN family BMP antagonist |
| NFIB | nuclear factor I/B |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PALM | paralemmin |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PAX8 | paired box 8 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCDHB3 | protocadherin beta 3 |
| PENK | proenkephalin |
| PHF1 | PHD finger protein 1 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLCG1 | phospholipase C, gamma 1 |
| POLQ | polymerase (DNA directed), theta |
| PRDM16 | PR domain containing 16 |
| RAC3 | ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3) |
| RGCC | regulator of cell cycle |
| RIN2 | Ras and Rab interactor 2 |
| RNF208 | ring finger protein 208 |
| SETD1B | SET domain containing 1B |
| SFI1 | Sfi1 homolog, spindle assembly associated (yeast) |
| SIK3 | SIK family kinase 3 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRRM2 | serine/arginine repetitive matrix 2 |
| STX1A | syntaxin 1A (brain) |
| SUGP1 | SURP and G patch domain containing 1 |
| TDRD3 | tudor domain containing 3 |
| THOP1 | thimet oligopeptidase 1 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRAK1 | trafficking protein, kinesin binding 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPYL2 | TSPY-like 2 |
| U2AF2 | U2 small nuclear RNA auxiliary factor 2 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| YPEL1 | yippee-like 1 (Drosophila) |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| YY2 | YY2 transcription factor |
| ZNF224 | zinc finger protein 224 |
| ZNF236 | zinc finger protein 236 |
| ZNF862 | zinc finger protein 862 |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADGRG2 | adhesion G protein-coupled receptor G2 |
| ADM | adrenomedullin |
| APLP1 | amyloid beta (A4) precursor-like protein 1 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMC4 | armadillo repeat containing 4 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| C1QTNF3 | C1q and tumor necrosis factor related protein 3 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| C5AR2 | complement component 5a receptor 2 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCNT1 | cyclin T1 |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLCN6 | chloride channel, voltage-sensitive 6 |
| CLSPN | claspin |
| CSF1R | colony stimulating factor 1 receptor |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DLST | dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) |
| DMC1 | DNA meiotic recombinase 1 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa |
| ERCC4 | excision repair cross-complementation group 4 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO5 | exonuclease 5 |
| FADS2 | fatty acid desaturase 2 |
| FAM188A | family with sequence similarity 188, member A |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FUZ | fuzzy planar cell polarity protein |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPATCH2L | G patch domain containing 2-like |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HELLS | helicase, lymphoid-specific |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4A | histone cluster 1, H4a |
| HIST1H4F | histone cluster 1, H4f |
| HPN | hepsin |
| IPP | intracisternal A particle-promoted polypeptide |
| KIAA0894 | KIAA0894 protein |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBTD1 | mbt domain containing 1 |
| MIS18BP1 | MIS18 binding protein 1 |
| MITF | microphthalmia-associated transcription factor |
| MPHOSPH8 | M-phase phosphoprotein 8 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OVOL1 | ovo-like zinc finger 1 |
| PCDHA9 | protocadherin alpha 9 |
| PGBD5 | piggyBac transposable element derived 5 |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POM121 | POM121 transmembrane nucleoporin |
| PRAMEF11 | PRAME family member 11 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SLC52A1 | solute carrier family 52 (riboflavin transporter), member 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SPRYD7 | SPRY domain containing 7 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TBC1D17 | TBC1 domain family, member 17 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM184C | transmembrane protein 184C |
| TMEM209 | transmembrane protein 209 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| UBQLN4 | ubiquilin 4 |
| USP36 | ubiquitin specific peptidase 36 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WFDC2 | WAP four-disulfide core domain 2 |
| WLS | wntless Wnt ligand secretion mediator |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| ZNF160 | zinc finger protein 160 |
| ZNF219 | zinc finger protein 219 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZNF816 | zinc finger protein 816 |