cyanocobalamin-4395 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the cyanocobalamin-4395 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AIF1 allograft inflammatory factor 1
ALOX5AP arachidonate 5-lipoxygenase-activating protein
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
BAAT bile acid CoA:amino acid N-acyltransferase
BCL6 B-cell CLL/lymphoma 6
C8ORF44 chromosome 8 open reading frame 44
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CDC14B cell division cycle 14B
CDC42 cell division cycle 42
CDK18 cyclin-dependent kinase 18
CEL carboxyl ester lipase
CELA3A chymotrypsin-like elastase family, member 3A
CLTB clathrin, light chain B
COL1A1 collagen, type I, alpha 1
CXCR6 chemokine (C-X-C motif) receptor 6
DEFB126 defensin, beta 126
DOC2B double C2-like domains, beta
DYM dymeclin
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
EFNA5 ephrin-A5
EYA3 EYA transcriptional coactivator and phosphatase 3
FSCN3 fascin actin-bundling protein 3, testicular
GP5 glycoprotein V (platelet)
GPR31 G protein-coupled receptor 31
GRIP2 glutamate receptor interacting protein 2
GSTM5 glutathione S-transferase mu 5
GYPC glycophorin C (Gerbich blood group)
HFE hemochromatosis
HLA-DMB major histocompatibility complex, class II, DM beta
HNF1B HNF1 homeobox B
HOXA7 homeobox A7
HOXB5 homeobox B5
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
IGFBP5 insulin-like growth factor binding protein 5
IGLJ3 immunoglobulin lambda joining 3
IL23A interleukin 23, alpha subunit p19
IL2RB interleukin 2 receptor, beta
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITM2C integral membrane protein 2C
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8
KIAA0319 KIAA0319
KLK8 kallikrein-related peptidase 8
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
LSP1 lymphocyte-specific protein 1
MAGEA5 melanoma antigen family A5
MALL mal, T-cell differentiation protein-like
MBD2 methyl-CpG binding domain protein 2
MCFD2 multiple coagulation factor deficiency 2
MED25 mediator complex subunit 25
MUC3B mucin 3B, cell surface associated
MYO15A myosin XVA
MYO9B myosin IXB
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NTS neurotensin
OPRL1 opiate receptor-like 1
OTOR otoraplin
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCDHB11 protocadherin beta 11
PCDHGA8 protocadherin gamma subfamily A, 8
PDIA2 protein disulfide isomerase family A, member 2
PIPOX pipecolic acid oxidase
PQLC3 PQ loop repeat containing 3
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PVRIG poliovirus receptor related immunoglobulin domain containing
RAB40B RAB40B, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
REC8 REC8 meiotic recombination protein
RERE arginine-glutamic acid dipeptide (RE) repeats
RUNDC3A RUN domain containing 3A
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SHANK2 SH3 and multiple ankyrin repeat domains 2
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLCO1A2 solute carrier organic anion transporter family, member 1A2
SSX3 synovial sarcoma, X breakpoint 3
TACSTD2 tumor-associated calcium signal transducer 2
TAF7L TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
TAOK2 TAO kinase 2
TBXA2R thromboxane A2 receptor
TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TMPRSS6 transmembrane protease, serine 6
TNK2 tyrosine kinase, non-receptor, 2
TRD T cell receptor delta locus
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA3C tubulin, alpha 3c
UBR2 ubiquitin protein ligase E3 component n-recognin 2
VCAN versican
VGLL3 vestigial-like family member 3
VWA5A von Willebrand factor A domain containing 5A
ZFP64 ZFP64 zinc finger protein
ZNF154 zinc finger protein 154

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTL8 actin-like 8
AFAP1 actin filament associated protein 1
ALOX15 arachidonate 15-lipoxygenase
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BAGE B melanoma antigen
BFSP1 beaded filament structural protein 1, filensin
BHLHE41 basic helix-loop-helix family, member e41
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC121 coiled-coil domain containing 121
CCDC85C coiled-coil domain containing 85C
CCNO cyclin O
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CRYGC crystallin, gamma C
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEF6 differentially expressed in FDCP 6 homolog (mouse)
DNM3 dynamin 3
DTX2 deltex 2, E3 ubiquitin ligase
EGFL7 EGF-like-domain, multiple 7
ERCC2 excision repair cross-complementation group 2
ERCC6 excision repair cross-complementation group 6
ERMAP erythroblast membrane-associated protein (Scianna blood group)
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GLB1L galactosidase, beta 1-like
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HIST1H1D histone cluster 1, H1d
HIST1H4D histone cluster 1, H4d
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
IRF2 interferon regulatory factor 2
IRF9 interferon regulatory factor 9
KLHL21 kelch-like family member 21
KPNA5 karyopherin alpha 5 (importin alpha 6)
LARP6 La ribonucleoprotein domain family, member 6
LMNB1 lamin B1
LOC157562 uncharacterized LOC157562
LOC729164 hCG1732469
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYPLA2P1 lysophospholipase II pseudogene 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MTCP1 mature T-cell proliferation 1
MX2 MX dynamin-like GTPase 2
N4BP3 NEDD4 binding protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDRG1 N-myc downstream regulated 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
OLFML2A olfactomedin-like 2A
PARP12 poly (ADP-ribose) polymerase family, member 12
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHB13 protocadherin beta 13
PCDHB3 protocadherin beta 3
PCSK7 proprotein convertase subtilisin/kexin type 7
PDE8B phosphodiesterase 8B
PGPEP1 pyroglutamyl-peptidase I
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
PRKCE protein kinase C, epsilon
PRR14L proline rich 14-like
PRSS16 protease, serine, 16 (thymus)
RAB11FIP5 RAB11 family interacting protein 5 (class I)
SLC12A8 solute carrier family 12, member 8
SLC22A14 solute carrier family 22, member 14
SLC52A1 solute carrier family 52 (riboflavin transporter), member 1
SPINK5 serine peptidase inhibitor, Kazal type 5
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TMA16 translation machinery associated 16 homolog (S. cerevisiae)
TMEM242 transmembrane protein 242
TPCN1 two pore segment channel 1
TPSG1 tryptase gamma 1
TRIM21 tripartite motif containing 21
TTF2 transcription termination factor, RNA polymerase II
TUBA3D tubulin, alpha 3d
UBQLN4 ubiquilin 4
VEGFB vascular endothelial growth factor B
WDR33 WD repeat domain 33
XYLT2 xylosyltransferase II
YY2 YY2 transcription factor
ZBED1 zinc finger, BED-type containing 1
ZBTB22 zinc finger and BTB domain containing 22
ZNF286A zinc finger protein 286A
ZNF552 zinc finger protein 552
ZNF573 zinc finger protein 573
ZNF701 zinc finger protein 701