| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the cyanocobalamin-4572 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM5 | ADAM metallopeptidase domain 5 (pseudogene) |
| ADRA1D | adrenoceptor alpha 1D |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AGBL2 | ATP/GTP binding protein-like 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AK5 | adenylate kinase 5 |
| ARHGAP28 | Rho GTPase activating protein 28 |
| ASTN2 | astrotactin 2 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CASR | calcium-sensing receptor |
| CGA | glycoprotein hormones, alpha polypeptide |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COL10A1 | collagen, type X, alpha 1 |
| CREM | cAMP responsive element modulator |
| CRISP2 | cysteine-rich secretory protein 2 |
| CRP | C-reactive protein, pentraxin-related |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DCSTAMP | dendrocyte expressed seven transmembrane protein |
| DTNA | dystrobrevin, alpha |
| EGR2 | early growth response 2 |
| ESRRG | estrogen-related receptor gamma |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FABP3 | fatty acid binding protein 3, muscle and heart |
| FOXD2 | forkhead box D2 |
| GAB1 | GRB2-associated binding protein 1 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSPT1 | G1 to S phase transition 1 |
| HECW1 | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1 |
| HIST1H3I | histone cluster 1, H3i |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HRASLS2 | HRAS-like suppressor 2 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IL1R1 | interleukin 1 receptor, type I |
| ING2 | inhibitor of growth family, member 2 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KDM8 | lysine (K)-specific demethylase 8 |
| KHK | ketohexokinase (fructokinase) |
| KIAA0368 | KIAA0368 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LMNA | lamin A/C |
| LRRN3 | leucine rich repeat neuronal 3 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MPZ | myelin protein zero |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| NDUFB7 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa |
| NIPAL2 | NIPA-like domain containing 2 |
| NPR1 | natriuretic peptide receptor 1 |
| OR10H3 | olfactory receptor, family 10, subfamily H, member 3 |
| PCDHB3 | protocadherin beta 3 |
| PCDHGA11 | protocadherin gamma subfamily A, 11 |
| PDE2A | phosphodiesterase 2A, cGMP-stimulated |
| PDLIM3 | PDZ and LIM domain 3 |
| PLA2G6 | phospholipase A2, group VI (cytosolic, calcium-independent) |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PRDM14 | PR domain containing 14 |
| PRKCDBP | protein kinase C, delta binding protein |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGER1 | prostaglandin E receptor 1 (subtype EP1), 42kDa |
| PTGIR | prostaglandin I2 (prostacyclin) receptor (IP) |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) |
| RABGAP1L | RAB GTPase activating protein 1-like |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 |
| RDH5 | retinol dehydrogenase 5 (11-cis/9-cis) |
| RHCE | Rh blood group, CcEe antigens |
| RIN3 | Ras and Rab interactor 3 |
| RPL10L | ribosomal protein L10-like |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SEMG2 | semenogelin II |
| SERHL2 | serine hydrolase-like 2 |
| SLC17A4 | solute carrier family 17, member 4 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC30A5 | solute carrier family 30 (zinc transporter), member 5 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| STOML1 | stomatin (EPB72)-like 1 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFSF11 | tumor necrosis factor (ligand) superfamily, member 11 |
| TRIM3 | tripartite motif containing 3 |
| UPK1B | uroplakin 1B |
| VCL | vinculin |
| WFDC2 | WAP four-disulfide core domain 2 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF268 | zinc finger protein 268 |
| ZNF44 | zinc finger protein 44 |
| Symbol | Name |
|---|---|
| AAAS | achalasia, adrenocortical insufficiency, alacrimia |
| ACBD4 | acyl-CoA binding domain containing 4 |
| ANKZF1 | ankyrin repeat and zinc finger domain containing 1 |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGEF1 | Rho guanine nucleotide exchange factor (GEF) 1 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ATG16L1 | autophagy related 16-like 1 (S. cerevisiae) |
| B3GNT2 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C1R | complement component 1, r subcomponent |
| C3 | complement component 3 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CA11 | carbonic anhydrase XI |
| CCNJL | cyclin J-like |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CES3 | carboxylesterase 3 |
| CFAP69 | cilia and flagella associated protein 69 |
| CHD8 | chromodomain helicase DNA binding protein 8 |
| CLDN14 | claudin 14 |
| CUL9 | cullin 9 |
| DENND4A | DENN/MADD domain containing 4A |
| DFFB | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EN2 | engrailed homeobox 2 |
| ERMAP | erythroblast membrane-associated protein (Scianna blood group) |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FANCC | Fanconi anemia, complementation group C |
| FCMR | Fc fragment of IgM receptor |
| FPGS | folylpolyglutamate synthase |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GREB1L | growth regulation by estrogen in breast cancer-like |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HCFC2 | host cell factor C2 |
| HPSE | heparanase |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IFI44L | interferon-induced protein 44-like |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IL17RB | interleukin 17 receptor B |
| IL7R | interleukin 7 receptor |
| INCENP | inner centromere protein antigens 135/155kDa |
| JUNB | jun B proto-oncogene |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KIAA1107 | KIAA1107 |
| LOC730101 | uncharacterized LOC730101 |
| LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LSM14B | LSM14B, SCD6 homolog B (S. cerevisiae) |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MXRA8 | matrix-remodelling associated 8 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| OSMR | oncostatin M receptor |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PDZD2 | PDZ domain containing 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| POR | P450 (cytochrome) oxidoreductase |
| PRKX | protein kinase, X-linked |
| PRMT7 | protein arginine methyltransferase 7 |
| PRPH | peripherin |
| PTDSS2 | phosphatidylserine synthase 2 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RAB4B | RAB4B, member RAS oncogene family |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RIN1 | Ras and Rab interactor 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF31 | ring finger protein 31 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SH3TC1 | SH3 domain and tetratricopeptide repeats 1 |
| SHPK | sedoheptulokinase |
| SIRAL2 | SIR2 antiphage like 2 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SPRYD7 | SPRY domain containing 7 |
| SYT17 | synaptotagmin XVII |
| TBC1D17 | TBC1 domain family, member 17 |
| TMEM2 | transmembrane protein 2 |
| TNRC6B | trinucleotide repeat containing 6B |
| TRIM21 | tripartite motif containing 21 |
| TUBA3C | tubulin, alpha 3c |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| USP18 | ubiquitin specific peptidase 18 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VN1R1 | vomeronasal 1 receptor 1 |
| WNT7A | wingless-type MMTV integration site family, member 7A |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZNF215 | zinc finger protein 215 |
| ZNF747 | zinc finger protein 747 |
| ZNF768 | zinc finger protein 768 |